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UBA2 Antikörper
UBA2
Reaktivität: Human
WB, IF, IHC (p)
Wirt: Kaninchen
Polyclonal
unconjugated
Produktdetails anti-UBA2 Antikörper
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Target
Alle UBA2 Antikörper anzeigen
UBA2
(SUMO1 Activating Enzyme Subunit 2 (UBA2))
Reaktivität
Alle Reaktivitäten für UBA2 Antikörper
Human
Wirt
Alle Wirte für UBA2 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für UBA2 Antikörper
Polyklonal
Konjugat
Alle Konjugate für UBA2 Antikörper
Dieser UBA2 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für UBA2 Antikörper
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Spezifität
This antibody detects endogenous levels of Uba2 protein. (region surrounding Ser621)
Kreuzreaktivität (Details)
Species reactivity (tested):Human.
Aufreinigung
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Reinheit
> 95 % pure by SDS-PAGE
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Anwendungsinformationen
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Applikationshinweise
ELISA: 1: 5000approx. 1: 10000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Konzentration
1,0 mg/mL
Buffer
Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
DO NOT FREEZE!
Lagerung
4 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C.
Details zu UBA2
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Target
UBA2
(SUMO1 Activating Enzyme Subunit 2 (UBA2))
Andere Bezeichnung
SAE2 / UBA2 (UBA2 Produkte )
Synonyme
ATSAE2 antikoerper, EMB2764 antikoerper, EMBRYO DEFECTIVE 2764 antikoerper, F3K23.23 antikoerper, F3K23_23 antikoerper, SUMO-ACTIVATING ENZYME 2 antikoerper, SUMO-activating enzyme 2 antikoerper, ARX antikoerper, SAE2 antikoerper, AA986091 antikoerper, Arx antikoerper, Sae2 antikoerper, UBA1 antikoerper, Ubl1a2 antikoerper, Uble1b antikoerper, sae2 antikoerper, sae2-B antikoerper, uba2-a antikoerper, uba2-b antikoerper, uble1b-B antikoerper, sae2b antikoerper, uble1b antikoerper, wu:fi17g06 antikoerper, zgc:66354 antikoerper, SUMO1 activating enzyme subunit 2 antikoerper, SUMO-activating enzyme 2 antikoerper, ubiquitin like modifier activating enzyme 2 antikoerper, ubiquitin-like modifier activating enzyme 2 antikoerper, ubiquitin like modifier activating enzyme 2 L homeolog antikoerper, MICPUN_63834 antikoerper, MICPUCDRAFT_36729 antikoerper, SAE2 antikoerper, UBA2 antikoerper, Uba2 antikoerper, uba2.L antikoerper, uba2 antikoerper
Hintergrund
The human UBiquitin Activating domain 2 (UBA2) gene is located on chromosome 19q12. Human UBA2 could form a beta mercaptoethanol-sensitive conjugate with members of the sentrin family, but not with ubiquitin of NEDD8 in the presence of AOS1. The recombinant proteins, Sua1p and hUba2, form a complex. In this complex, hUba2 binds SUMO-1, which gives the complex the activity of the SUMO-1 activating enzyme. Therefore, UBA2 has been found to be a component of the sentrin-activating enzyme complex.Synonyms: ARX, Anthracycline-associated resistance ARX, HRIHFB2115, SUMO-activating enzyme subunit 2, UBLE1B, Ubiquitin-like 1-activating enzyme E1B
Molekulargewicht
approx. 71 kDa
Gen-ID
10054
NCBI Accession
NP_005490
UniProt
Q9UBT2
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