Rpb1 CTD Antikörper (Thr4)

Produktnummer ABIN2668543

Produktdetails anti-Rpb1 CTD Antikörper

Target: Rpb1 CTD (RNA Polymerase II CTD)

Bindungsspezifität: Thr4

Reaktivität: Human

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser Rpb1 CTD Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Chromatin Immunoprecipitation (ChIP)

Aufreinigung: Protein G Chromatography

Immunogen: This antibody was raised against a synthetic peptide corresponding to RNA Pol II CTD phosphorylated at threonine 4.

Klon: 6D7

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 μg/μL

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung:

Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Lagerung: -20 °C

Informationen zur Lagerung: Antibodies in solution can be stored at -20 °C for 2 years.

Haltbarkeit: 6 months

Referenzen für anti-Rpb1 CTD Antikörper (ABIN2668543)

Harlen, Trotta, Smith, Mosaheb, Fuchs, Churchman: "Comprehensive RNA Polymerase II Interactomes Reveal Distinct and Varied Roles for Each Phospho-CTD Residue." in: Cell reports, Vol. 15, Issue 10, pp. 2147-2158, (2016) (PubMed).

Laitem, Zaborowska, Isa, Kufs, Dienstbier, Murphy: "CDK9 inhibitors define elongation checkpoints at both ends of RNA polymerase II-transcribed genes." in: Nature structural & molecular biology, Vol. 22, Issue 5, pp. 396-403, (2015) (PubMed).

Hintermair, Heidemann, Koch, Descostes, Gut, Gut, Fenouil, Ferrier, Flatley, Kremmer, Chapman, Andrau, Eick: "Threonine-4 of mammalian RNA polymerase II CTD is targeted by Polo-like kinase 3 and required for transcriptional elongation." in: The EMBO journal, Vol. 31, Issue 12, pp. 2784-97, (2012) (PubMed).

Mayer, Heidemann, Lidschreiber, Schreieck, Sun, Hintermair, Kremmer, Eick, Cramer: "CTD tyrosine phosphorylation impairs termination factor recruitment to RNA polymerase II." in: Science (New York, N.Y.), Vol. 336, Issue 6089, pp. 1723-5, (2012) (PubMed).

Details zu Rpb1 CTD

Target: Rpb1 CTD (RNA Polymerase II CTD)

Andere Bezeichnung: RNA Pol II CTD (Rpb1 CTD Produkte)

Synonyme: 5 antikoerper, 8WG16 antikoerper, CG1554 antikoerper, CTD antikoerper, Dmel\\CG1554 antikoerper, H5 antikoerper, II antikoerper, L5 antikoerper, POL antikoerper, Pol II antikoerper, Pol II CTD antikoerper, Pol II Ser5P antikoerper, Pol II0[ser2] antikoerper, Pol II0[ser5] antikoerper, Pol II[ser2] antikoerper, Pol IIa antikoerper, Pol IIo antikoerper, Pol IIo[Ser2] antikoerper, Pol IIo[ser2] antikoerper, Pol IIo[ser5] antikoerper, Pol-IIa antikoerper, PolII antikoerper, PolIIo antikoerper, RNA Pol II antikoerper, RNA Pol II CTD antikoerper, RNA PolI 215 antikoerper, RNA PolII antikoerper, RNA pol II antikoerper, RNA pol IIo antikoerper, RNA polII antikoerper, RNAP antikoerper, RNAP II antikoerper, RNAP II LS antikoerper, RNAPII antikoerper, RNAPII0 antikoerper, RNApol2 antikoerper, RNApolII antikoerper, RPB1 antikoerper, RPII215 antikoerper, RpII antikoerper, Rpb1 antikoerper, Rpll215 antikoerper, Ubl antikoerper, dRPB1 antikoerper, dRpb1 antikoerper, l(1)10Ca antikoerper, l(1)DC912 antikoerper, l(1)DF912 antikoerper, l(1)G0040 antikoerper, l(1)L5 antikoerper, pol II antikoerper, polII antikoerper, RNA polymerase II 215kD subunit antikoerper, RpII215 antikoerper

Molekulargewicht: 240 kDa

Gen-ID: 5430