PTGER2 Antikörper

Produktnummer ABIN264447

Produktdetails anti-PTGER2 Antikörper

Target: PTGER2 (Prostaglandin E Receptor 2 (Subtype EP2), 53kDa (PTGER2))

Reaktivität: Human, Ratte, Rind (Kuh)

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PTGER2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: This antibody detects Prostaglandin E2 Receptor EP2 subtype.

Produktmerkmale: Synonyms: Prostaglandin E receptor 2, Prostanoid EP2 receptor, Prostaglandin E2 receptor EP2, PGEreceptor EP2, PGE2 receptor EP2 subtype, EP2

Aufreinigung: Protein A/G Chromatography

Immunogen: Hybridoma produced by the fusion of splenocytes from mice immunized with recombinanthuman EP2 receptor protein and mouse myeloma cells.

Klon: 3-00E-006

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Western Blot: 1-5 μg/mL. Positive Control: Porcine brain lysate.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.08 % Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody (in aliquots) at -20 °C. Can be shipped at 2-8 °C. Avoid repeated freezing and thawing.
Shelf life: One year from despatch.

Haltbarkeit: 12 months

Details zu PTGER2

Target: PTGER2 (Prostaglandin E Receptor 2 (Subtype EP2), 53kDa (PTGER2))

Andere Bezeichnung: PTGER2 (PTGER2 Produkte)

Synonyme: EP2 antikoerper, Ptgerep2 antikoerper, ptger2 antikoerper, ptger2l antikoerper, zgc:63974 antikoerper, MGC69060 antikoerper, PTGER2 antikoerper, Ptger-ep2 antikoerper, si:ch211-13n20.1 antikoerper, si:dkey-29m11.3 antikoerper, zgc:136608 antikoerper, prostaglandin E receptor 2 antikoerper, prostaglandin E receptor 2 (subtype EP2) antikoerper, prostaglandin E receptor 2a (subtype EP2) antikoerper, prostaglandin E receptor 2 S homeolog antikoerper, prostaglandin E receptor 2b (subtype EP2) antikoerper, PTGER2 antikoerper, Ptger2 antikoerper, ptger2a antikoerper, ptger2.S antikoerper, ptger2b antikoerper

Hintergrund: Prostaglandins (PG's) are produced by the metabolism of arachidonic acid. PGE-2 is one of the five physiologically significant prostanoids known. It's wide spectrum of physiologic and pharmacologic effects in various tissues are mediated through binding to the PGE-2 receptors (EP1, EP2, EP3 & EP4). These include effects on the immune, endocrine, cardiovascular, renal and reproductive systems as well as smooth muscle. It is also one of the most abundant of the prostanoid family in the brain where it plays an important role in many neural functions, particularly in newborn babies, and as a mediator of inflammation. PGE-2 signals through a family of G-protein coupled receptors known as EP receptors. There are 4 subtypes of EP receptors, known as EP1, EP2, EP3 and EP4. EP2 receptors are 358 amino acid proteins with a short third intracellular loop. EP2 receptors stimulate adenylyl cyclase by their coupling to Gs and do not undergo PGE-2-induced internalization. The EP2 receptors is involved with the contration and relaxation of smooth muscle tissue. These receptors are mainly localized in lung and placental tissues and in smooth muscle.Synonyms: EP2, PGE receptor EP2, PGE2 receptor EP2 subtype, Prostaglandin E receptor 2, Prostaglandin E2 receptor EP2, Prostanoid EP2 receptor

Gen-ID: 5732

UniProt: P43116