RNF14 Antikörper

Produktnummer ABIN2461721

Produktdetails anti-RNF14 Antikörper

Target: RNF14 (Ring Finger Protein 14 (RNF14))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RNF14 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Aufreinigung: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RNF14.

Anwendungsinformationen

Applikationshinweise: RNF14 antibody can be used for detection of RNF14 by ELISA at 1:312500. RNF14 antibody can be used for detection of RNF14 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store RNF14 antibody at -20 °C.

Details zu RNF14

Target: RNF14 (Ring Finger Protein 14 (RNF14))

Andere Bezeichnung: RNF14 (RNF14 Produkte)

Synonyme: ARA54 antikoerper, HFB30 antikoerper, TRIAD2 antikoerper, 2310075C09Rik antikoerper, 2610005D23Rik antikoerper, AA986456 antikoerper, AU041447 antikoerper, D18Ertd188e antikoerper, D7Bwg0165e antikoerper, Triad2 antikoerper, ring finger protein 14 antikoerper, RNF14 antikoerper, Rnf14 antikoerper

Hintergrund: RNF14 contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A dominant negative mutant of this gene has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins.The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A dominant negative mutant of this gene has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins. Five alternatively spliced transcript variants encoding two distinct isoforms have been reported.

Molekulargewicht: 52 kDa, 54 kDa, 40 kDa, 54 kDa, 54 kDa

Gen-ID: 9604

NCBI Accession: NP_899648

UniProt: Q9UBS8

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling