Kv2.2 Antikörper (N-Term)

Produktnummer ABIN1881474

Produktdetails anti-Kv2.2 Antikörper

Target: Kv2.2 (KCNB2) (Potassium Voltage-Gated Channel, Shab-Related Subfamily, Member 2 (KCNB2))

Bindungsspezifität: AA 138-166, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Kv2.2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Homologie: B, M, Rb

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This KCNB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 138-166 amino acids from the N-terminal region of human KCNB2.

Klon: RB40837

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-Kv2.2 Antikörper (ABIN1881474)

Cirulli, Kasperaviciūte, Attix, Need, Ge, Gibson, Goldstein: "Common genetic variation and performance on standardized cognitive tests." in: European journal of human genetics : EJHG, Vol. 18, Issue 7, pp. 815-20, (2010) (PubMed).

Baranzini, Wang, Gibson, Galwey, Naegelin, Barkhof, Radue, Lindberg, Uitdehaag, Johnson, Angelakopoulou, Hall, Richardson, Prinjha, Gass, Geurts, Kragt, Sombekke, Vrenken, Qualley, Lincoln et al.: "Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis...." in: Human molecular genetics, Vol. 18, Issue 4, pp. 767-78, (2009) (PubMed).

Nyholt, LaForge, Kallela, Alakurtti, Anttila, Färkkilä, Hämaläinen, Kaprio, Kaunisto, Heath, Montgomery, Göbel, Todt, Ferrari, Launer, Frants, Terwindt, de Vries, Verschuren, Brand: "A high-density association screen of 155 ion transport genes for involvement with common migraine." in: Human molecular genetics, Vol. 17, Issue 21, pp. 3318-31, (2008) (PubMed).

Wu, Ma, Brown, Geisler, Li, Tzeng, Jia, Jurisica, Li: "Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening." in: Proteomics, Vol. 7, Issue 11, pp. 1775-85, (2007) (PubMed).

Hanna, Kruskal, Ezekowitz, Bloom, Collier: "Role of macrophage oxidative burst in the action of anthrax lethal toxin." in: Molecular medicine (Cambridge, Mass.), Vol. 1, Issue 1, pp. 7-18, (1996) (PubMed).

Details zu Kv2.2

Target: Kv2.2 (KCNB2) (Potassium Voltage-Gated Channel, Shab-Related Subfamily, Member 2 (KCNB2))

Andere Bezeichnung: KCNB2 (KCNB2 Produkte)

Synonyme: KCNB2 antikoerper, si:ch211-193n21.1 antikoerper, Kv2.2 antikoerper, 9630047L19Rik antikoerper, BB130875 antikoerper, XShab12 antikoerper, kcnb2 antikoerper, KV2.2 antikoerper, potassium voltage-gated channel subfamily B member 2 antikoerper, potassium voltage-gated channel, Shab-related subfamily, member 2 antikoerper, potassium channel, voltage gated Shab related subfamily B, member 2 antikoerper, potassium voltage gated channel, Shab-related subfamily, member 2 antikoerper, potassium channel, voltage gated Shab related subfamily B, member 2 S homeolog antikoerper, KCNB2 antikoerper, kcnb2 antikoerper, LOC100051372 antikoerper, Kcnb2 antikoerper, kcnb2.S antikoerper

Hintergrund: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shab-related subfamily. This member is a delayed rectifier potassium channel. The gene is expressed in gastrointestinal smooth muscle cells.

Molekulargewicht: 102563

NCBI Accession: NP_004761

UniProt: Q92953