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ATP6AP2 Antikörper (AA 205-234)
ATP6AP2
Reaktivität: Human
WB
Wirt: Kaninchen
Polyclonal
RB41871
unconjugated
Produktnummer ABIN1881092
Produktdetails anti-ATP6AP2 Antikörper
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Target
Alle ATP6AP2 Antikörper anzeigen
ATP6AP2
(ATPase, H+ Transporting, Lysosomal Accessory Protein 2 (ATP6AP2))
Bindungsspezifität
Alle Epitope für ATP6AP2 Antikörper
AA 205-234
Reaktivität
Alle Reaktivitäten für ATP6AP2 Antikörper
Human
Wirt
Alle Wirte für ATP6AP2 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für ATP6AP2 Antikörper
Polyklonal
Konjugat
Alle Konjugate für ATP6AP2 Antikörper
Dieser ATP6AP2 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für ATP6AP2 Antikörper
Western Blotting (WB)
Aufreinigung
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This ATP6AP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 205-234 amino acids from the Central region of human ATP6AP2.
Klon
RB41871
Isotyp
Ig Fraction
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Alternativen
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Anwendungsinformationen
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Applikationshinweise
WB: 1:1000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Haltbarkeit
6 months
Referenzen für anti-ATP6AP2 Antikörper (ABIN1881092)
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Takahashi, Yamamoto, Hirose, Hiraishi, Shoji, Shibasaki, Kato, Kaneko, Sasano, Satoh, Totsune : "Expression of (pro)renin receptor in human kidneys with end-stage kidney disease due to diabetic nephropathy. " in: Peptides , Vol. 31 , Issue 7 , pp. 1405-8 , (2010 ) (PubMed ).
Cruciat, Ohkawara, Acebron, Karaulanov, Reinhard, Ingelfinger, Boutros, Niehrs : "Requirement of prorenin receptor and vacuolar H+-ATPase-mediated acidification for Wnt signaling. " in: Science (New York, N.Y.) , Vol. 327 , Issue 5964 , pp. 459-63 , (2010 ) (PubMed ).
Nabi, Biswas, Nakagawa, Ichihara, Inagami, Suzuki : "Prorenin has high affinity multiple binding sites for (pro)renin receptor. " in: Biochimica et biophysica acta , Vol. 1794 , Issue 12 , pp. 1838-47 , (2009 ) (PubMed ).
Alcazar, Cousins, Striker, Marin-Castano : "(Pro)renin receptor is expressed in human retinal pigment epithelium and participates in extracellular matrix remodeling. " in: Experimental eye research , Vol. 89 , Issue 5 , pp. 638-47 , (2009 ) (PubMed ).
Takemitsu, Ichihara, Kaneshiro, Sakoda, Kurauchi-Mito, Narita, Kinouchi, Yamashita, Itoh : "Association of (pro)renin receptor mRNA expression with angiotensin-converting enzyme mRNA expression in human artery. " in: American journal of nephrology , Vol. 30 , Issue 4 , pp. 361-70 , (2009 ) (PubMed ).
Details zu ATP6AP2
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Target
ATP6AP2
(ATPase, H+ Transporting, Lysosomal Accessory Protein 2 (ATP6AP2))
Andere Bezeichnung
ATP6AP2 (ATP6AP2 Produkte )
Synonyme
APT6M8-9 antikoerper, ATP6IP2 antikoerper, ATP6M8-9 antikoerper, ELDF10 antikoerper, M8-9 antikoerper, MRXE antikoerper, MSTP009 antikoerper, XMRE antikoerper, (P)RR antikoerper, 5730403E06Rik antikoerper, Atp6ip2 antikoerper, tj6 antikoerper, wss antikoerper, arcl antikoerper, j6b7 antikoerper, stv1 antikoerper, tj6m antikoerper, tj6s antikoerper, vph1 antikoerper, atp6a2 antikoerper, atp6n1d antikoerper, ATP6AP2 antikoerper, DKFZp459G0918 antikoerper, atp6ap2 antikoerper, wu:fj36c03 antikoerper, wu:fq15e04 antikoerper, zgc:73194 antikoerper, ATPase H+ transporting accessory protein 2 antikoerper, ATPase, H+ transporting, lysosomal accessory protein 2 antikoerper, ATPase H+ transporting V0 subunit d2 antikoerper, ATPase H+ transporting V0 subunit a2 antikoerper, ATPase, H+ transporting, lysosomal accessory protein 2 S homeolog antikoerper, ATP6AP2 antikoerper, Atp6ap2 antikoerper, ATP6V0D2 antikoerper, atp6v0a2 antikoerper, atp6ap2.S antikoerper, atp6ap2 antikoerper
Hintergrund
This gene encodes a protein that is associated with adenosine triphosphatases (ATPases). Proton-translocating ATPases have fundamental roles in energy conservation, secondary active transport, acidification of intracellular compartments, and cellular pH homeostasis. There are three classes of ATPases- F, P, and V. The vacuolar (V-type) ATPases have a transmembrane proton-conducting sector and an extramembrane catalytic sector. The encoded protein has been found associated with the transmembrane sector of the V-type ATPases.
Molekulargewicht
39008
NCBI Accession
NP_005756
UniProt
O75787
Pathways
ACE Inhibitor Pathway , Peptide Hormone Metabolism , Regulation of Systemic Arterial Blood Pressure by Hormones
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