PTP4A2 Antikörper (AA 58-162)

Produktnummer ABIN1724901

Produktdetails anti-PTP4A2 Antikörper

Target: PTP4A2 (Protein tyrosine Phosphatase Type IVA, Member 2 (PTP4A2))

Bindungsspezifität: AA 58-162

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PTP4A2 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human PTP4A2 (AA: 58-162) expressed in E. coli.

Klon: 5B6F4

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Referenzen für anti-PTP4A2 Antikörper (ABIN1724901)

Hardy, Wong, Muller, Park, Tremblay: "Overexpression of the protein tyrosine phosphatase PRL-2 correlates with breast tumor formation and progression." in: Cancer research, Vol. 70, Issue 21, pp. 8959-67, (2010) (PubMed).

Akiyama, Dhavan, Yi: "PRL-2 increases Epo and IL-3 responses in hematopoietic cells." in: Blood cells, molecules & diseases, Vol. 44, Issue 4, pp. 209-14, (2010) (PubMed).

Details zu PTP4A2

Target: PTP4A2 (Protein tyrosine Phosphatase Type IVA, Member 2 (PTP4A2))

Andere Bezeichnung: PTP4A2 (PTP4A2 Produkte)

Synonyme: wu:fc05f09 antikoerper, wu:fi84b06 antikoerper, zgc:101724 antikoerper, MGC53390 antikoerper, MGC80084 antikoerper, MGC132077 antikoerper, PTP4A2 antikoerper, ptp4a2 antikoerper, Prl-2 antikoerper, HH13 antikoerper, HH7-2 antikoerper, HU-PP-1 antikoerper, OV-1 antikoerper, PRL-2 antikoerper, PRL2 antikoerper, PTP4A antikoerper, PTPCAAX2 antikoerper, ptp-IV1a antikoerper, ptp-IV1b antikoerper, protein tyrosine phosphatase type IVA, member 2b antikoerper, protein tyrosine phosphatase 4a2 antikoerper, protein tyrosine phosphatase type IVA, member 2 antikoerper, protein tyrosine phosphatase type IVA, member 2 L homeolog antikoerper, ptp4a2b antikoerper, ptp4a2 antikoerper, PTP4A2 antikoerper, ptp4a2.L antikoerper, Ptp4a2 antikoerper

Hintergrund:

Description: The protein encoded by this gene belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. PTPs in this class contain a protein tyrosine phosphatase catalytic domain and a characteristic C-terminal prenylation motif. This PTP has been shown to primarily associate with plasmic and endosomal membrane through its C-terminal prenylation. This PTP was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which suggested its role in tumorigenesis. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 11, 12 and 17. ,

Aliases: HH13, OV-1, PRL2, HH7-2, PRL-2, PTP4A, HU-PP-1, PTPCAAX2, ptp-IV1a, ptp-IV1b

Molekulargewicht: 19.1 kDa

Gen-ID: 8073

HGNC: 8073