KLF1 Antikörper (AA 208-362)
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- Target Alle KLF1 Antikörper anzeigen
- KLF1 (Kruppel-Like Factor 1 (erythroid) (KLF1))
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Bindungsspezifität
- AA 208-362
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser KLF1 Antikörper ist unkonjugiert
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Applikation
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
- Aufreinigung
- purified
- Immunogen
- Purified recombinant fragment of human KLF1 (AA: 208-362) expressed in E. coli.
- Klon
- 1B6A3
- Isotyp
- IgG1
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- Applikationshinweise
- ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, FCM: 1:200 - 1:400
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- 4°C, -20°C for long term storage
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Transcription factors KLF1 and KLF2 positively regulate embryonic and fetal beta-globin genes through direct promoter binding." in: The Journal of biological chemistry, Vol. 286, Issue 28, pp. 24819-27, (2011) (PubMed).
: "KLF1 regulates BCL11A expression and gamma- to beta-globin gene switching." in: Nature genetics, Vol. 42, Issue 9, pp. 742-4, (2010) (PubMed).
: "
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Transcription factors KLF1 and KLF2 positively regulate embryonic and fetal beta-globin genes through direct promoter binding." in: The Journal of biological chemistry, Vol. 286, Issue 28, pp. 24819-27, (2011) (PubMed).
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- Target
- KLF1 (Kruppel-Like Factor 1 (erythroid) (KLF1))
- Andere Bezeichnung
- KLF1 (KLF1 Produkte)
- Synonyme
- KLF1 antikoerper, EKLF antikoerper, HBFQTL6 antikoerper, INLU antikoerper, Eklf antikoerper, Nan antikoerper, Kruppel-like factor 1 (erythroid) antikoerper, Kruppel like factor 1 antikoerper, KLF-4 antikoerper, KLF1 antikoerper, Klf1 antikoerper
- Hintergrund
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Description: This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In(Lu) blood phenotype. , ,
Aliases: EKLF, INLU, HBFQTL6
- Molekulargewicht
- 38.2 kDa
- Gen-ID
- 10661
- HGNC
- 10661
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