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CLEC7A Antikörper (Middle Region)

CLEC7A Reaktivität: Human, Maus, Ratte WB, IHC (p), IF, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1449932
  • Target Alle CLEC7A Antikörper anzeigen
    CLEC7A (C-Type Lectin Domain Family 7, Member A (CLEC7A))
    Bindungsspezifität
    • 14
    • 8
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    • 58
    • 37
    • 5
    • 1
    Human, Maus, Ratte
    Wirt
    • 40
    • 19
    • 19
    Kaninchen
    Klonalität
    • 41
    • 32
    Polyklonal
    Konjugat
    • 26
    • 11
    • 11
    • 8
    • 7
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CLEC7A Antikörper ist unkonjugiert
    Applikation
    • 44
    • 38
    • 25
    • 23
    • 8
    • 8
    • 8
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human, Mouse, Rat.
    Aufreinigung
    Affinity chromatography purified via peptide column
    Immunogen
    17 amino acid synthetic peptide near the center of Human CLEC7A
    Isotyp
    IgG
    Top Product
    Discover our top product CLEC7A Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    PBS containing 0.02 % Sodium Azide as preservative
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    CLEC7A (C-Type Lectin Domain Family 7, Member A (CLEC7A))
    Andere Bezeichnung
    CLEC7A / Dectin-1 (CLEC7A Produkte)
    Synonyme
    CLEC7A antikoerper, BGR antikoerper, Clecsf12 antikoerper, beta-GR antikoerper, CANDF4 antikoerper, CLECSF12 antikoerper, DECTIN1 antikoerper, Clec7b antikoerper, RGD1565140 antikoerper, C-type lectin domain containing 7A antikoerper, C-type lectin domain family 7, member a antikoerper, CLEC7A antikoerper, Clec7a antikoerper
    Hintergrund
    CLEC7A, also known as dectin-1, is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily and is predominantly expressed on myeloid cells. It is a small glycoprotein type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif (ITAM). CLEC7A functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Upon fungal exposure, CLEC7A activates Syk tyrosine kinase, triggering a massive oxidative burst through the formation of reactive oxygen species.Synonyms: BGR, Beta-glucan receptor, C-type lectin domain family 7 member A, C-type lectin superfamily member 12, CLECSF12, DC-associated C-type lectin 1, DECTIN1, Dendritic cell-associated C-type lectin 1
    Gen-ID
    64581
    NCBI Accession
    NP_922938
    Pathways
    Activation of Innate immune Response
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