IFNB1 Antikörper

Produktnummer ABIN121882

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch IFNB1 in WB, IP und Func. Es zeigt Reaktivität gegenüber Proben von Huhn.

Kurzübersicht für IFNB1 Antikörper (ABIN121882)

Target: IFNB1 (Interferon, beta 1, Fibroblast (IFNB1))

Reaktivität: Huhn

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IFNB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Functional Studies (Func)

Produktdetails anti-IFNB1 Antikörper

Spezifität: This antibody recognizes Interferon beta (chIFN-beta). This antibody does not cross react with IFN gamma. This antiserum neutralizes chIFN-beta and can be used to discriminate IFN alpha and IFN beta bioactivities.

Produktmerkmale: Synonyms: IFN-beta, IFNB1, IFB, Fibroblast interferon

Aufreinigung: Affinity chromatography on protein G

Immunogen: Recombinant chicken Interferon Beta

Anwendungsinformationen

Applikationshinweise: Immunoprecipitation. Western Blot: This antibody detects a band of approximately 20 kDa. Funktional Assays.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu IFNB1

Target: IFNB1 (Interferon, beta 1, Fibroblast (IFNB1))

Andere Bezeichnung: IFNB / Interferon beta

Hintergrund: Reports suggest that chIFN exhibits properties similar to mammalian IFN type I (IFNI). Functional studies revealed the presence of two distantly related IFNI genes, designated as IFN alpha and IFN beta, found on chicken chromosome Z. The serological distinction between these two IFNs has been verified using neutralisation assays, and there is evidence that the antiviral activity of chIFN-beta is approximately tenfold less compared to chIFN-alpha. This would suggest that chIFNbeta might have a different physiological role, though chIFN-beta is expressed strongly in virus-infected cells.Synonyms: Fibroblast interferon, IFB, IFN-beta, IFNB1

Gen-ID: 554219

UniProt: Q90873

Pathways: JAK-STAT Signalweg, T-Zell Rezeptor Signalweg, TLR Signalweg, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Autophagie, Inflammasome