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CD226 Antikörper (FITC)

CD226 Reaktivität: Human FACS Wirt: Maus Monoclonal DX11 FITC
Produktnummer ABIN119796
  • Target Alle CD226 Antikörper anzeigen
    CD226
    Reaktivität
    • 74
    • 20
    • 5
    • 4
    • 2
    • 1
    • 1
    Human
    Wirt
    • 54
    • 23
    • 8
    Maus
    Klonalität
    • 49
    • 35
    • 1
    Monoklonal
    Konjugat
    • 46
    • 10
    • 9
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD226 Antikörper ist konjugiert mit FITC
    Applikation
    • 45
    • 32
    • 32
    • 16
    • 14
    • 9
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Spezifität
    This antibody recognises CD226. Clone DX11 is reported to inhibit T- and NK cell mediated cytotoxicity against tumour cell targets and to block TNF alpha and IFN gamma secretion by alloantigen-specific T-cells. We recommend the use of SM2023A for funtional studies.
    Aufreinigung
    Affinity chromatography on Protein G
    Immunogen
    Human cytotoxic T lymphocyte clone. Spleen cells from immunised BALB/c mouse were fused with cells of the Sp2/0 myeloma cell line.
    Klon
    DX11
    Isotyp
    IgG1
    Top Product
    Discover our top product CD226 Primärantikörper
  • Applikationshinweise
    Flow Cytometry: 1/10 - 1/20, Use 10 μL of the suggested working dilution to label 1 x 10^6 cells in 100 μL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.1 mg/mL
    Buffer
    PBS, pH 7.4 containing 0.09 % Sodium Azide and 1.0 % Bovine Serum Albumin
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    CD226
    Andere Bezeichnung
    CD226 / DNAM1 (CD226 Produkte)
    Synonyme
    CD226 antikoerper, cd226 antikoerper, zgc:158817 antikoerper, BC051526 antikoerper, DNAM-1 antikoerper, DNAM1 antikoerper, Pta1 antikoerper, TLiSA1 antikoerper, PTA1 antikoerper, CD226 molecule antikoerper, CD226 antigen antikoerper, CD226 antikoerper, cd226 antikoerper, Cd226 antikoerper
    Hintergrund
    CD226 is a 65kD glycoprotein, also known as DNAM1 (DNAX accessory molecule-1). CD226 is broadly expressed on T-cells, NK cells, platelets, monocytes and a subset of B cells. CD226 is also expressed by a subset of CD3 positive thymocytes.Synonyms: DNAM-1, DNAX accessory molecule 1
    Gen-ID
    10666
    NCBI Accession
    NP_006557
    UniProt
    Q15762
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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