IL25 Antikörper (Interleukin 25) (Biotin)

Details for Product anti-IL25 Antibody No. ABIN1043795, Anbieter: Anmelden zum Anzeigen
Antigen
  • IL25
  • Il25
  • Ly6elg
  • IL17E
  • IL-17e
  • Il17e
  • RGD1561632
  • interleukin 25
  • myeloid derived growth factor
  • IL25
  • Mydgf
  • Il25
Reaktivität
Human
200
93
18
1
Wirt
Maus
110
74
44
26
Klonalität (Klon)
Monoklonal ()
Konjugat
Dieser IL25 Antikörper ist konjugiert mit Biotin
17
15
12
10
9
9
8
8
7
5
5
5
5
5
4
4
4
4
4
4
4
4
1
1
1
1
1
1
1
1
Applikation
Flow Cytometry (FACS), Western Blotting (WB)
174
96
77
48
32
19
16
13
5
5
4
3
2
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen Anti-IL-17E (MOUSE) Monoclonal Antibody was produced in mouse by repeated immunizations with mature full length recombinant human IL-17E produced in E.coli followed by hybridoma development.
Immunogen Type: RecombinantProtein
Klon 11K8B1
Isotyp IgG1
Spezifität This product was purified from concentrated tissure culture supernate by Protein G chromatography followed by extensive dialysis against the buffer stated above. This antibody is specific for human IL-17E protein. A BLAST analysis was used to suggest cross-reactivity with IL-17E from human sources based on 100% homology with the immunizing sequence. Cross-reactivity with IL-17E from other sources has not been determined.
Produktmerkmale Anti-IL17E recognizes IL-17E (also known as IL25). IL-17E is produced and secreted by intra-epithelial lymphocytes, lung epithelial cells, alveolar macrophages, eosinophils, basophils, NKT cells, mast cells and cells of the gastro-intestinal tract and uterus. IL-17E stimulates the production of Th2-type cytokines. IL-17E limits Th17 cell development by inducing the expression of IL-13 by dendritic cells or by inhibiting IL-23 production by macrophages. Induces activation of NF-kappa-B and stimulates production of the proinflammatory chemokine IL-8. A number of cytokines, including IL-17E, have been implicated as oncogenes, reflecting the importance of these proteins in cell growth and survival. Anti-IL-17E cytokine antibody is ideal for investigators involved in Immunology, Signal Transduction research, Cancer and pro-inflammatory pathologies.
Reinigung purified
Andere Bezeichnung IL-17E (IL25 Antibody Abstract)
Hintergrund Anti-IL17E recognizes IL-17E (also known as IL25). IL-17E is produced and secreted by intra-epithelial lymphocytes, lung epithelial cells, alveolar macrophages, eosinophils, basophils, NKT cells, mast cells and cells of the gastro-intestinal tract and uterus. IL-17E stimulates the production of Th2-type cytokines. IL-17E limits Th17 cell development by inducing the expression of IL-13 by dendritic cells or by inhibiting IL-23 production by macrophages. Induces activation of NF-kappa-B and stimulates production of the proinflammatory chemokine IL-8. A number of cytokines, including IL-17E, have been implicated as oncogenes, reflecting the importance of these proteins in cell growth and survival. Anti-IL-17E cytokine antibody is ideal for investigators involved in Immunology, Signal Transduction research, Cancer and pro-inflammatory pathologies.
Synonyms: Interleukin 25, IL-25, Interleukin 17E, IL-17E
Gen-ID 64806
NCBI Accession NP_073626
UniProt Q9H293
Applikationshinweise This purified antibody has been tested for use in Flow Cytometry and western blotting. Specific conditions for reactivity should be optimized by the end user.
Kommentare

Gene Name: IL25

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Lyophilized
Rekonstitution Reconstitution Buffer: Restore with deionized water (or equivalent), Reconstitution Volume: 100 µL
Konzentration 1.0 mg/mL
Buffer 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2, 10 mg/mL Bovine Serum Albumin (BSA) - Immunoglobulin and Protease free
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store vial at 4 °C prior to restoration. For extended storage aliquot contents and freeze at -20 °C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening.
Haltbarkeit 12 months
Bilder des Herstellers
 image for anti-Interleukin 25 (IL25) antibody (Biotin) (ABIN1043795) anti-Interleukin 25 (IL25) antibody (Biotin)
 image for anti-Interleukin 25 (IL25) antibody (Biotin) (ABIN1043795) anti-Interleukin 25 (IL25) antibody (Biotin) (Image 2)
Produkt verwendet in: Conti, Shen, Nayyar, Stocum, Sun, Lindemann, Ho, Hai, Yu, Jung, Filler, Masso-Welch, Edgerton, Gaffen: "Th17 cells and IL-17 receptor signaling are essential for mucosal host defense against oral candidiasis." in: The Journal of experimental medicine, Vol. 206, Issue 2, pp. 299-311, 2009 (PubMed).

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