anti-NLRC4 (NLRC4) Antikörper

Bezeichnung:
anti-NLR Family, CARD Domain Containing 4 Antikörper (NLRC4)
Auf www.antikoerper-online.de finden Sie aktuell 95 NLR Family, CARD Domain Containing 4 (NLRC4) Antikörper von 22 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen NLRC4 Kits (13) und NLRC4 Proteine (3) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 116 NLRC4 Produkte verfügbar.
Synonyme:
9530011P19Rik, Card12, CLAN, CLAN1, CLANA, CLANB, CLANC, CLAND, CLR2.1, IPAF
Alle Antikörper anzeigen Gen GeneID UniProt
NLRC4 58484 Q9NPP4
NLRC4 268973  
NLRC4 298784  

Alle Spezies anzeigen

Weitere Synonyme anzeigen

Meistgesuchte Reaktivitäten zu anti-NLRC4 (NLRC4) Antikörper

Wählen Sie die Spezies und Applikation aus

anti-Human NLRC4 Antikörper:

anti-Mouse (Murine) NLRC4 Antikörper:

anti-Rat (Rattus) NLRC4 Antikörper:

Alle verfügbaren anti-NLRC4 Antikörper

Sie gelangen zu unserer vorgefilterten Suche.

Am meisten referenzierte anti-NLRC4 Antikörper

  1. Human Monoclonal NLRC4 Primary Antibody für FACS - ABIN2665296 : Cai, Batra, Wakamatsu, Pacher, Jeyaseelan: NLRC4 inflammasome-mediated production of IL-1β modulates mucosal immunity in the lung against gram-negative bacterial infection. in Journal of immunology (Baltimore, Md. : 1950) 2012 (PubMed)
    Zeige alle 5 Referenzen für 2665296

  2. Guinea Pig Polyclonal NLRC4 Primary Antibody für IHC, WB - ABIN2792097 : Clark, Gurney, Abaya, Baker, Baldwin, Brush, Chen, Chow, Chui, Crowley, Currell, Deuel, Dowd, Eaton, Foster, Grimaldi, Gu, Hass, Heldens, Huang, Kim, Klimowski, Jin, Johnson, Lee, Lewis, Liao, Mark et al.: The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. ... in Genome research 2003 (PubMed)
    Zeige alle 2 Referenzen für 2792097

  3. Human Polyclonal NLRC4 Primary Antibody für IHC (fro), IHC (p) - ABIN252142 : Akhter, Caution, Abu Khweek, Tazi, Abdulrahman, Abdelaziz, Voss, Doseff, Hassan, Azad, Schlesinger, Wewers, Gavrilin, Amer: Caspase-11 promotes the fusion of phagosomes harboring pathogenic bacteria with lysosomes by modulating actin polymerization. in Immunity 2012 (PubMed)

  4. Human Polyclonal NLRC4 Primary Antibody für WB - ABIN153028 : Cividini, Tozzi, Galli, Pesi, Camici, Dumontet, Jordheim, Allegrini: Cytosolic 5'-nucleotidase II interacts with the leucin rich repeat of NLR family member Ipaf. in PLoS ONE 2015 (PubMed)

  5. Human Polyclonal NLRC4 Primary Antibody für WB - ABIN657230 : Vinzing, Eitel, Lippmann, Hocke, Zahlten, Slevogt, Nguessan, Günther, Schmeck, Hippenstiel, Flieger, Suttorp, Opitz: NAIP and Ipaf control Legionella pneumophila replication in human cells. in Journal of immunology (Baltimore, Md. : 1950) 2008 (PubMed)

Weitere Antikörper gegen NLRC4 Interaktionspartner

Human NLR Family, CARD Domain Containing 4 (NLRC4) Interaktionspartner

  1. The authors describe a novel mutation in NLRC4 in a large pedigree causing an NLRC4-associated, partially anakinra-responsive AID, dominated by cutaneous erythematous nodes and urticarial rash, arthralgias, and late-onset enterocolitis.

  2. Results found that NLRC4 expression increased in for promoting DN progression and demonstrate NLRC4-driven IL-1beta (zeige IL1B Antikörper) production as critical for the progression of DN.

  3. Ubiquitin-tagged NLRC4 could induce cell death and activate caspase-8 (zeige CASP8 Antikörper) independent of Ser (zeige SIGLEC1 Antikörper)(533) phosphorylation. Our

  4. LPS (zeige IRF6 Antikörper) activates the MAPK (zeige MAPK1 Antikörper) pathway in macrophages, thus resulting in the upregulation of NLRC4; however, NLRC4 inhibits IL1beta (zeige IL1B Antikörper) and IL18 (zeige IL18 Antikörper) production, contributing to the anti-inflammatory response.

  5. High expression of NLRP3 (zeige NLRP3 Antikörper), NLRC4, and CASP1 (zeige CASP1 Antikörper) in background non-tumorous liver is significantly correlated with poor prognosis of patients after resection of hepatocellular carcinoma.

  6. association of IL-18 (zeige IL18 Antikörper) levels with a single nucleotide polymorphism in the untranslated exon 2 of the inflammasome component NLRC4

  7. While both contributing to pathogen clearance, NLRP3 (zeige NLRP3 Antikörper) more than NLRC4 contributes to deleterious inflammatory responses in cystic fibrosis (zeige S100A8 Antikörper) and correlates with defective NLRC4-dependent IL-1Ra (zeige IL1RN Antikörper) production.

  8. analysis of a subset of inflammasome receptors including NLRP3 (zeige NLRP3 Antikörper), NLRC4 and AIM2 (zeige AIM2 Antikörper) that triggers formation of the micrometer-sized spherical supramolecular complex called the ASC (zeige PYCARD Antikörper) speck

  9. Thus, pathogenic inflammasome activity during Candida infection is negatively regulated by the IL-22 (zeige IL22 Antikörper)/NLRC4/IL-1Ra (zeige IL1RN Antikörper) axis.

  10. cN-II (zeige NT5C2 Antikörper) co-immunoprecipitated both with wild type Ipaf and its LRR domain after transfection with corresponding expression vectors, but not with Ipaf lacking the LRR domain.

Mouse (Murine) NLR Family, CARD Domain Containing 4 (NLRC4) Interaktionspartner

  1. NLRC4 expression controls melanoma tumor growth.

  2. The interplay between NLRP3 (zeige NLRP3 Antikörper) and NLRC4 reveals an unexpected overlap between what had been considered distinct inflammasome scaffolds.

  3. The activation of NLRC4 by flagellin (zeige FliC Antikörper) downregulated the flagellin (zeige FliC Antikörper)-induced and TLR5 (zeige TLR5 Antikörper)-mediated immune responses against flagellin (zeige FliC Antikörper).

  4. TLR5 (zeige TLR5 Antikörper) but not NLRC4 is required for S. pneumoniae FliC (zeige FliC Antikörper)-induced protection.

  5. Data indicate that NLRC4 activation in Intestinal epithelial cells (IECs) leads to cell expulsion and IL-18 (zeige IL18 Antikörper) release, and implicate Caspase-8 (zeige CASP8 Antikörper) in NLRC4 inflammasome responses in vivo by generation of doubly deficient in Caspase-1 (zeige CASP1 Antikörper) and Caspase-8 (zeige CASP8 Antikörper).

  6. The tick protein sialostatin L2 binds to annexin A2 (zeige ANXA2 Antikörper) and inhibits NLRC4-mediated inflammasome activation.

  7. LPS (zeige TLR4 Antikörper) activates the MAPK (zeige MAPK1 Antikörper) pathway in macrophages, thus resulting in the upregulation of NLRC4; however, NLRC4 inhibits IL1beta (zeige IL1B Antikörper) and IL18 (zeige IL18 Antikörper) production, contributing to the anti-inflammatory response.

  8. These data reveal mild constitutive activation of the Nlrc4 inflammasome as the results of two SNPs, which leads to the stimulation of hepatocyte proliferation. The increased liver regeneration induces rapid liver mass recovery after hepatectomy and may prevent the development of hepatotoxin-induced liver fibrosis.

  9. While both contributing to pathogen clearance, NLRP3 (zeige NLRP3 Antikörper) more than NLRC4 contributes to deleterious inflammatory responses in cystic fibrosis (zeige S100A8 Antikörper) and correlates with defective NLRC4-dependent IL-1Ra (zeige IL1RN Antikörper) production.

  10. The wheel-like structure of a PrgJ-NAIP2-NLRC4 complex determined by cryogenic electronmicroscopy at 6.6 angstrom reveals that NLRC4 activation involves substantial structural reorganization that creates one oligomerization surface (catalytic surface).

NLRC4 Antigen-Profil

Beschreibung des Gens

In C. elegans, Ced4 binds and activates Ced3, an apoptotic initiator caspase, via caspase-associated recruitment domains (CARDs). Human Ced4 homologs include APAF1 (MIM 602233), NOD1/CARD4 (MIM 605980), and NOD2/CARD15 (MIM 605956). These proteins have at least 1 N-terminal CARD domain followed by a centrally located nucleotide-binding domain (NBD or NACHT) and a C-terminal regulatory domain, found only in mammals, that contains either WD40 repeats or leucine-rich repeats (LRRs). CARD12 is a member of the Ced4 family and can induce apoptosis.

Alternative names and synonyms associated with NLRC4

  • NLR family, CARD domain containing 4 (NLRC4) Antikörper
  • NLR family, CARD domain containing 4 (Nlrc4) Antikörper
  • 9530011P19Rik Antikörper
  • Card12 Antikörper
  • CLAN Antikörper
  • CLAN1 Antikörper
  • CLANA Antikörper
  • CLANB Antikörper
  • CLANC Antikörper
  • CLAND Antikörper
  • CLR2.1 Antikörper
  • IPAF Antikörper

Bezeichner auf Proteinebene für NLRC4

caspase recruitment domain protein 12 , NLR family CARD domain-containing protein 4 , ice protease-activating factor , ipaf , NLR family, CARD domain containing 4 , CARD, LRR, and NACHT-containing protein , ICE-protease activating factor , NOD-like receptor C4 , caspase recruitment domain family, member 12 , caspase recruitment domain-containing protein 12 , nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 4

GENE ID SPEZIES
459135 Pan troglodytes
512480 Bos taurus
706378 Macaca mulatta
100070605 Equus caballus
58484 Homo sapiens
268973 Mus musculus
298784 Rattus norvegicus
Ausgewählte Anbieter für anti-NLRC4 (NLRC4) Antikörper
Haben Sie etwas anderes gesucht?