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High ATP6AP2 expression is associated with Renal Damage.
serum s(P)RR could be used as a marker for atherosclerotic conditions in hemodialysis patients
(P)RR may contribute to the homeostatic control of erythropoiesis.
Placental (P)RR can be involved in blood pressure regulation via the tissue RAS. On the other hand, plasma s(P)RR may be involved in the pathogenesis of decreased renal function in preeclampsia.
the present results suggest that ATP6AP2 rs5918007T might be susceptible factors for Essential Hypertension in Chinese Han population.
Study identifies a renin (zeige REN ELISA Kits)-angiotensin system-independent function for the (P)RR in the regulation of LDL metabolism by controlling the levels of SORT1 (zeige SORT1 ELISA Kits) and LDL receptor (zeige LDLR ELISA Kits).
Demonstrate that there are strong interactions between prorenin, ATP6AP2, and TGFB1 (zeige TGFB1 ELISA Kits) and that this system has a greater capacity in female amnion to stimulate profibrotic pathways, thus maintaining the integrity of the fetal membranes.
a novel GLP1R (zeige GLP1R ELISA Kits) Interacting Protein ATP6ap2
Crosstalk between (Pro)renin receptor and COX-2 (zeige COX2 ELISA Kits) in the renal medulla during angiotensin II-induced hypertension
This is the first demonstration that (P)RR may be profoundly involved in ductal tumorigenesis in the pancreas.
Ureter bud PRR (zeige PVRL1 ELISA Kits) performs essential functions during UB branching and collecting duct morphogenesis via control of a hierarchy of genes that control UB branching and terminal differentiation of the collecting duct cells.
ATP6AP2 disruption leads to cognitive impairment and neurodegeneration, mimicking aspects of the neuropathology associated with ATP6AP2 mutations in humans.
These findings demonstrate a cell-autonomous requirement for the PRR (zeige PVRL1 ELISA Kits) within nephron progenitors for progenitor maintenance.
Atp6ap2 may form a complex with H+-ATPases in proximal tubule and intercalated cells but that prorenin has no acute effect on H+-ATPase (zeige ATP6AP1 ELISA Kits) activity in intercalated cells.
Data suggest that high glucose (as in hyperglycemia) decreases autophagy and increases apoptosis in podocytes via activation of (pro)renin receptor (Atp6ap2) and PI3K/Akt (zeige AKT1 ELISA Kits)/mTOR (zeige FRAP1 ELISA Kits) signaling pathway.
ANG II (zeige AGT ELISA Kits) acts via AT1R (zeige AGTRAP ELISA Kits) to upregulate PRR (zeige PVRL1 ELISA Kits) expression both in cultured cells and in DOCA-salt hypertensive mice by increasing CREB (zeige CREB1 ELISA Kits) binding to the PRR (zeige PVRL1 ELISA Kits) promoter.
nephron PRR (zeige PVRL1 ELISA Kits) may be important in water regulation by modulating the AVP (zeige AVP ELISA Kits)/V2R (zeige AVPR2 ELISA Kits)/AQP2 (zeige AQP2 ELISA Kits) pathway
the v-ATPase (zeige ATP6V1H ELISA Kits) ATP6AP2 does not appear to have a fusion-promoting role in the formation of phagolysosomes
ATPase H+ transporting lysosomal accessory protein 2 is critical for granule cell fate and morphogenesis.
This gene encodes a protein that is associated with adenosine triphosphatases (ATPases). Proton-translocating ATPases have fundamental roles in energy conservation, secondary active transport, acidification of intracellular compartments, and cellular pH homeostasis. There are three classes of ATPases- F, P, and V. The vacuolar (V-type) ATPases have a transmembrane proton-conducting sector and an extramembrane catalytic sector. The encoded protein has been found associated with the transmembrane sector of the V-type ATPases.
V-type proton ATPase subunit d 2
, V-ATPase subunit d 2
, vacuolar proton pump subunit d 2
, ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d
, ATPase, H+ transporting, lysosomal V0 subunit A2
, ATPase, H+ transporting, lysosomal V0 subunit a
, ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
, ATPase, H+ transporting, lysosomal accessory protein 2
, Renin receptor
, V-type proton ATPase subunit d 2-like
, v-type proton ATPase subunit d 2-like
, ATPase H(+)-transporting lysosomal-interacting protein 2
, ATPase, H+ transporting, lysosomal (vacuolar proton pump) membrane sector associated protein M8-9
, ATPase, H+ transporting, lysosomal interacting protein 2
, ER-localized type I transmembrane adaptor
, V-ATPase M8.9 subunit
, embryonic liver differentiation factor 10
, renin receptor
, renin/prorenin receptor
, vacuolar ATP synthase membrane sector-associated protein M8-9
, vacuolar proton ATP synthase membrane sector associated protein M8-9
, (pro)renin receptor
, ATPase, H+ transporting, lysosomal interacting protein 1
, ATPase, H(+)-transporting, lysosomal-interacting protein 2
, ATPase H(+)-transporting lysosomal accessory protein 2