anti-tyrosyl-DNA phosphodiesterase 2 (TDP2) Antikörper

TDP2 encodes a member of a superfamily of divalent cation-dependent phosphodiesterases. Zusätzlich bieten wir Ihnen TDP2 Proteine (12) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
TDP2 51567 O95551
TDP2 56196 Q9JJX7
TDP2 498749 Q3T1H5
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Top anti-TDP2 Antikörper auf antikoerper-online.de

Showing 10 out of 88 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB <b>WB Suggested Anti-TTRAP Antibody Titration: </b>0.2-1 ug/ml<br><b>Positive Control: </b>HepG2 cell lysate <b>Sample:</b> 1. DT40 (5x10<sup>5</sup>cells)<br>2. DT40 + rec. hTDP2 (5x10<sup>5</sup>cells)<br>3. soluble HIS-hTDP2 (5x10<sup>5</sup>cells)<br>4. pellet HIS-hTDP2 (5x10<sup>5</sup>cells)<b><br></b><b>Primary dilution:</b>1:1000<br><b>Secondary Antibod</b>y: dakocytomation Goat anti-rabbit<br><b>Secondary dilution:</b> 1:5000<br><b>Image Submitted by</b>: Keith Caldecott<br>University of Sussex 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Human Kaninchen Unkonjugiert FACS, IF, IHC (p), WB Confocal immunofluorescent analysis of EAPII Antibody (C-term)(ABIN655180) with A549 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red). DAPI was used to stain the cell nuclear (blue). 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), IP, WB Immunohistochemistry-Paraffin: ETS1 associated protein II Antibody [NBP1-46178] - Human colon carcinoma. Antibody used at a dilution of 1:200 (1ug/mg). Western Blot: ETS1 associated protein II Antibody [NBP1-46178] - Whole cell lysate from HeLa (5, 15 and 50 mcg for WB; 1 mg for IP, 20% of IP loaded) and 293T (T; 50 mcg) cells. Antibodies: Affinity purified rabbit anti-TDP2 antibody used for WB at 0.04 mcg/ml (A) and 0.4 mcg/ml (B) and used for IP at 3 mcg/mg lysate. TDP2 was also immunoprecipitated by another rabbit anti-TDP2 antibody, which recognizes a downstream epitope. 0.1 mL Anmelden zum Anzeigen 2 bis 4 Tage
371,00 €
Details
Fledermaus Kaninchen Unkonjugiert IHC (p), WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
653,02 €
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Human Kaninchen Unkonjugiert EIA, FACS, IF, IHC (p), WB   0.4 mL Anmelden zum Anzeigen 8 bis 11 Tage
357,50 €
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Human Kaninchen Unkonjugiert IHC (p), WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
517,00 €
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Human Kaninchen Unkonjugiert WB 0.1 mL Anmelden zum Anzeigen 2 bis 4 Tage
291,00 €
Details
Human Kaninchen Unkonjugiert IHC (p), WB Human Kidney (formalin-fixed, paraffin-embedded) stained with TTRAP antibody ABIN214210 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
501,70 €
Details
Human Kaninchen Unkonjugiert ICC, IF, WB Western Blot: ETS1 associated protein II Antibody [NBP2-16386] - Sample (30 ug of whole cell lysate) A: HCT116 10% SDS PAGE gel, diluted at 1:3000. Immunocytochemistry/Immunofluorescence: ETS1 associated protein II Antibody [NBP2-16386] - Confocal immunofluorescence analysis of paraformaldehyde-fixed HeLa, using EAPII antibody (Green) at 1:500 dilution. Alpha-tubulin filaments are labeled with Alpha-tubulin antibody (Red) at 1:2000. 0.1 mL Anmelden zum Anzeigen 3 bis 6 Tage
341,00 €
Details
Human Maus Unkonjugiert IF, WB Western Blot analysis of TTRAP expression in transfected 293T cell line by TTRAP MaxPab polyclonal antibody.<br><br>Lane 1: TTRAP transfected lysate(39.82 KDa).<br>Lane 2: Non-transfected lysate.<br> Immunofluorescence of <u>purified</u> MaxPab antibody to TTRAP on Hs 181.Tes cell. [antibody concentration 10 ug/ml] 50 μg Anmelden zum Anzeigen 7 bis 8 Tage
369,60 €
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TDP2 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-TDP2 Antikörper

  1. Human Polyclonal TDP2 Primary Antibody für ICC, IF - ABIN4309668 : Virgen-Slane, Rozovics, Fitzgerald, Ngo, Chou, van der Heden van Noort, Filippov, Gershon, Semler: An RNA virus hijacks an incognito function of a DNA repair enzyme. in Proceedings of the National Academy of Sciences of the United States of America 2012 (PubMed)

  2. Human Polyclonal TDP2 Primary Antibody für IF, WB - ABIN526818 : Thomson, Watson, Caldecott, Denneny, Depledge, Hamilton, Hopkins, Jordan, Morrow, Raoof, Waddell, Ogilvie: Generation of assays and antibodies to facilitate the study of human 5'-tyrosyl DNA phosphodiesterase. in Analytical biochemistry 2013 (PubMed)

  3. Cow (Bovine) Polyclonal TDP2 Primary Antibody für IHC, WB - ABIN2777707 : Pei, Yordy, Leng, Zhao, Watson, Li: EAPII interacts with ETS1 and modulates its transcriptional function. in Oncogene 2003 (PubMed)
    Show all 2 Pubmed References

Weitere Antikörper gegen TDP2 Interaktionspartner

Human tyrosyl-DNA phosphodiesterase 2 (TDP2) Interaktionspartner

  1. Both the genome instability and cell death of MRE11 (zeige MRE11A Antikörper)-null and MRE11 (zeige MRE11A Antikörper)-mutated H129N cells are significantly reversed by overexpression of Tdp2, an enzyme that eliminates covalent Top2 (zeige TOP2A Antikörper) conjugates; thus, the essential role of Mre11 (zeige MRE11A Antikörper) nuclease (zeige DCLRE1C Antikörper) activity is likely to remove the DNA lesions.

  2. Study revealed a post-translational regulation of TDP2 activity and discovered a new role of ERK3 (zeige MAPK4 Antikörper) in increasing cancer cells' DNA damage response and chemoresistance to Top2 (zeige TOP2A Antikörper) inhibitors.

  3. Data show that DNA-repair enzyme (zeige LIG4 Antikörper) TDP2 knockdown in HepG2 cells significantly delays the conversion of relaxed circular DNA (RC-DNA) to covalently closed circular (ccc) DNA.

  4. This article summarizes and compares the biochemistry, functions, and post-translational regulation of TDP1 (zeige TDP1 Antikörper) and TDP2, as well as the relevance of TDP1 (zeige TDP1 Antikörper) and TDP2 as determinants of response to anticancer agents

  5. Proteolytic degradation of Top2 (zeige TOP2A Antikörper) enables the processing of Top2 (zeige TOP2A Antikörper).DNA and Top2 (zeige TOP2A Antikörper).RNA covalent complexes by TDP2.

  6. TDP2 protects transcription from abortive topoisomerase activity and is required for normal neural function.

  7. Mutations in the 5'-tyrosyl-DNA phosphodiesterase activity of TTRAP,in particular TTRAP(E152A), showed decreased inhibitory activity on cell growth.

  8. Magnesium is indispensable for a 5'-tyrosyl DNA phosphodiesterase activity.

  9. VPg unlinkase activity in different mammalian cell lines correlates with their differential expression of TDP2.

  10. Biochemical characterization of human tyrosyl-DNA phosphodiesterase 2 (TDP2/TTRAP): a Mg(2 (zeige MUC7 Antikörper)+)/Mn(2+)-dependent phosphodiesterase specific for the repair of topoisomerase cleavage complexes.

Mouse (Murine) tyrosyl-DNA phosphodiesterase 2 (TDP2) Interaktionspartner

  1. The results collectively provide a structural mechanism for Tdp2 engagement of heterogeneous DNA damage that causes Top2 (zeige TOP2 Antikörper) poisoning.

  2. data show that TDP2 activity potentiates enterovirus infections and, in the case of coxsackievirus B3, is a required host function following virus infection of mouse cells

  3. our data reveal TDP2-mediated error-free NHEJ as an efficient and accurate mechanism to repair TOP2 (zeige TOP2 Antikörper)-induced DSBs

  4. Evidence implicates Tdp2 in the repair of Top1 (zeige TOP1 Antikörper)-mediated DNA damage in cultured cells and in vivo, in the absence of Tdp1 (zeige TDP1 Antikörper).

  5. the protein associates with TGF-beta (zeige TGFB1 Antikörper) receptors and components of the TRAF6 (zeige TRAF6 Antikörper)-TAK1 (zeige NR2C2 Antikörper) signaling module

Zebrafish tyrosyl-DNA phosphodiesterase 2 (TDP2) Interaktionspartner

  1. although the role of Smad (zeige SMAD1 Antikörper) proteins in mediating Nodal signaling is well-documented, the functional characterization of Ttrap provides insight into a novel Smad (zeige SMAD1 Antikörper) partner that plays an essential role in the fine-tuning of this signal transduction cascade

TDP2 Antigen-Profil

Protein Überblick

This gene encodes a member of a superfamily of divalent cation-dependent phosphodiesterases. The encoded protein associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor associated factors (TRAFs), and inhibits nuclear factor-kappa-B activation. This protein has sequence and structural similarities with APE1 endonuclease, which is involved in both DNA repair and the activation of transcription factors.

Genbezeichner und Symbole assoziert mit TDP2

  • tyrosyl-DNA phosphodiesterase 2 (TDP2) Antikörper
  • tyrosyl-DNA phosphodiesterase 2 (tdp2) Antikörper
  • tyrosyl-DNA phosphodiesterase 2 (Tdp2) Antikörper
  • tyrosyl-DNA phosphodiesterase 2b (tdp2b) Antikörper
  • ad022 Antikörper
  • D13Ertd656e Antikörper
  • dJ30M3.3 Antikörper
  • eap2 Antikörper
  • EAPII Antikörper
  • hTDP2 Antikörper
  • tdp2 Antikörper
  • Ttrap Antikörper
  • ttrapl Antikörper

Bezeichner auf Proteinebene für TDP2

5'-Tyr-DNA phosphodiesterase , 5'-tyrosyl-DNA phosphodiesterase , ETS1-associated protein 2 , ETS1-associated protein II , TRAF and TNF receptor associated protein , TRAF and TNF receptor-associated protein , VPg unlinkase , tyr-DNA phosphodiesterase 2 , tyrosyl-RNA phosphodiesterase , TRAF and TNF receptor-associated protein homolog , Tyr-DNA phosphodiesterase 2 , Traf and Tnf receptor associated protein , immune transcriptional repressor , traf and tnf receptor associated protein, like , tyrosyl-DNA phosphodiesterase 2

GENE ID SPEZIES
51567 Homo sapiens
100049743 Xenopus laevis
421007 Gallus gallus
507579 Bos taurus
56196 Mus musculus
498749 Rattus norvegicus
553516 Danio rerio
Ausgewählte Anbieter für anti-TDP2 (TDP2) Antikörper
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