anti-serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 6 (SERPINA6) Antikörper

SERPINA6 encodes an alpha-globulin protein with corticosteroid-binding properties. Zusätzlich bieten wir Ihnen SERPINA6 Kits (44) und SERPINA6 Proteine (37) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
SERPINA6 12401 Q06770
SERPINA6 866 P08185
SERPINA6 299270 P31211
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Top anti-SERPINA6 Antikörper auf antikoerper-online.de

Showing 10 out of 144 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB Host: Rabbit Target Name: SERPINA6 Sample Type: Hela Whole Cell lysates Antibody Dilution: 1.0ug/ml 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert ICC, IHC (p), WB Anti-Cortisol Binding Globulin antibody, ICC ICC: HEPG2 Cell Anti-Cortisol Binding Globulin antibody, Western blotting Lane 1: HELA Cell Lysate Lane 2: A431 Cell Lysate Lane 3: U87 Cell Lysate Lane 4: 22RV1 Cell Lysate Lane 5: PANC Cell Lysate 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$200.00
Details
Human Kaninchen Unkonjugiert IF, WB Confocal immunofluorescent analysis of SERPINA6 Antibody (Center) (ABIN654693) with 293 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert EIA, IF, WB Confocal immunofluorescent analysis of SERPINA6 Antibody (Center) Cat.-No AP53859PU-N with 293 cell followed by Alexa Fluor 488-conjugated Goat anti-Rabbit lgG (green). DAPI was used to stain the cell nuclear (blue). Western blot analysis of SERPINA6 Antibody (Center) Cat.-No AP53859PU-N in Mouse kidney tissue lysates (35ug/lane). This demonstrates the SERPINA6 antibody detected the SERPINA6 protein (arrow). 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Ratte Ziege Unkonjugiert ELISA, WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$610.50
Details
Human Kaninchen Unkonjugiert ELISA, WB 100 μL Anmelden zum Anzeigen 16 Days
$181.73
Details
Ratte Kaninchen Unkonjugiert WB 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$245.00
Details
Human Ziege Unkonjugiert IHC (p), ELISA Human Uterus (formalin-fixed, paraffin-embedded) stained with SERPINA6 antibody ABIN462399 followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen. 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$451.00
Details
Ratte Ziege Unkonjugiert ELISA, WB 0.1 mg Anmelden zum Anzeigen 2 bis 3 Tage
$481.25
Details
Human Ziege Unkonjugiert EIA, IHC (p) Human Uterus (formalin-fixed, paraffin-embedded) stained with SERPINA6followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen. 50 μg Anmelden zum Anzeigen 6 bis 8 Tage
$500.50
Details

SERPINA6 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-SERPINA6 Antikörper

  1. Rat (Rattus) Polyclonal SERPINA6 Primary Antibody für ELISA, WB - ABIN625826 : Romero, Holmgren-Holm, Grasa, Esteve, Remesar, Fernández-López, Alemany: Modulation in Wistar rats of blood corticosterone compartmentation by sex and a cafeteria diet. in PLoS ONE 2013 (PubMed)

Weitere Antikörper gegen SERPINA6 Interaktionspartner

Mouse (Murine) serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 6 (SERPINA6) Interaktionspartner

  1. CBG is involved in the gender differences observed in corticosteroids circulating levels and plays a role in the local regulation of corticosteroids availability in organs like lung.

  2. the same gene encodes brain and liver corticosteroid-binding globulin

  3. Data suggest fine control interaction between plasma CBG upregulation and stress-induced corticosterone (CORT (zeige CORT Antikörper)) release in mouse model of psychological stress; CBG appears to function in maintaining dynamic equilibrium between CBG-bound/-unbound CORT (zeige CORT Antikörper).

  4. Sequencing analysis showed that Cbg cDNA obtained from the mouse hypothalamus was homologous to Cbg cDNA obtained from the liver.

  5. Cbg-/- mice, unlike controls, remain insensitive to stress applied before memory retrieval. Furthermore, under stress conditions, we observed a blunted surge of corticosterone (CORT (zeige CORT Antikörper)) in plasma and no free CORT (zeige CORT Antikörper) rise in the hippocampus of Cbg-/-.

  6. study describes functional hyporesponsiveness and aldosterone resistance in distal colon of CBG(-/-) mice; steroid actions require an intrinsic but unknown function of CBG, which allows the sufficient supply of the hormone/s to the target tissue

  7. Critical role of plasma Cbg in providing an adequate endocrine and behavioral response to stress.

  8. These data suggest an active role for CBG in bioavailability, local delivery, and/or cellular signal transduction of glucocorticoids that extends beyond a function as a mere cargo transporter.

Human serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 6 (SERPINA6) Interaktionspartner

  1. In conclusion, site-specific CBG N-glycosylation regulates the bioavailability of cortisol in inflamed environments by fine-tuning the RCL (zeige C6orf108 Antikörper) proteolysis by endogenous and exogenous elastases.

  2. The results suggest reduced CBG cleavage in central obesity, possibly contributing to the characteristic inflammatory phenotype of the central obesity and metabolic syndrome.

  3. Corticosteroid-binding globulin cleavage may be pathogen-dependent in bloodstream infection

  4. Data indicate there was no significant circadian variation in serum cortisol-binding globulin (CBG) concentration in any of the 4 groups.

  5. Human cardiomyocytes express mineralocorticoid receptors, but are mostly free of nuclear glucocorticoid receptors. CBG is expressed in myocardium and in Purkinje fibers. CBG in heart is colocalized with mineralocorticoid receptor (zeige NR3C2 Antikörper).

  6. SERPINA6-rs1998056 regulated by FOXA/ERalpha (zeige ESR1 Antikörper) might be associated with female HCC (zeige FAM126A Antikörper) risk

  7. genetic variation in the SERPINA6 gene may be associated with altered CBG levels during adolescence.

  8. the results suggest that DEX repression of Corticosteroid-binding globulin involves tethering of the glucocorticoid receptor (zeige NR3C1 Antikörper) to C/EBPb (zeige CEBPB Antikörper).

  9. 8 naturally occurring CBG mutants with abnormalities in cortisol-binding affinity, cortisol-binding capacity, production/secretion, sensitivity to proteolytic cleavage of the reactive center loop, or recognition by monoclonal antibodies used for ELISAs were identified

  10. The study investigate the half-life of intact and elastase cleaved CBG in the rabbit. The half-lives of intact and cleaved human CBG are 10 h and identical.

Pig (Porcine) serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 6 (SERPINA6) Interaktionspartner

  1. non-synonymous polymorphisms of SERPINA6, particularly SNPs c.919G>A and c.44G>T/c.622C>T, are associated with cortisol level, HPA (zeige HPSE Antikörper) axis activity, and carcass and meat quality traits

  2. Cbg gene is a key regulator of cortisol levels and obesity susceptibility.

  3. Negative relationship exists between plasma cortisol and CBG under conditions of acute stress.

SERPINA6 Antigen-Profil

Protein Überblick

This gene encodes an alpha-globulin protein with corticosteroid-binding properties. This is the major transport protein for glucorticoids and progestins in the blood of most vertebrates. The gene localizes to a chromosomal region containing several closely related serine protease inhibitors which may have evolved by duplication events.

Genbezeichner und Symbole assoziert mit SERPINA6

  • serpin family A member 6 (SERPINA6) Antikörper
  • serpin family A member 6 L homeolog (serpina6.L) Antikörper
  • corticosteroid-binding globulin (LOC490838) Antikörper
  • serine (or cysteine) peptidase inhibitor, clade A, member 6 (Serpina6) Antikörper
  • serpin family A member 6 (Serpina6) Antikörper
  • AI265318 Antikörper
  • AV104445 Antikörper
  • CBG Antikörper
  • ep45-A Antikörper
  • SERPINA6 Antikörper

Bezeichner auf Proteinebene für SERPINA6

CBG , corticosteroid-binding globulin , serpin A6 , transcortin , serine protease inhibitor A6 , estrogen-regulated protein EP45 , serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 , corticosteroid binding globulin , serine (or cysteine) proteinase inhibitor, clade A, member 6 , serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 , serine (or cysteine) peptidase inhibitor, clade A, member 6 , serpin peptidase inhibitor, clade A, member 6

GENE ID SPEZIES
100172888 Pongo abelii
373636 Xenopus laevis
453131 Pan troglodytes
490838 Canis lupus familiaris
701121 Macaca mulatta
100356417 Oryctolagus cuniculus
12401 Mus musculus
866 Homo sapiens
299270 Rattus norvegicus
396736 Sus scrofa
101118224 Ovis aries
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