anti-phosphodiesterase 6C, CGMP-Specific, Cone, alpha Prime (PDE6C) Antikörper

PDE6C encodes the alpha-prime subunit of cone phosphodiesterase, which is composed of a homodimer of two alpha-prime subunits and 3 smaller proteins of 11, 13, and 15 kDa. Zusätzlich bieten wir Ihnen und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
PDE6C 110855 Q91ZQ1
PDE6C 361752  
PDE6C 5146 P51160
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Top anti-PDE6C Antikörper auf antikoerper-online.de

Showing 10 out of 28 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert IHC (p), WB Western blot analysis of PDE6C Antibody (Center) (ABIN653683) in mouse liver tissue lysates (35 µg/lane). PDE6C (arrow) was detected using the purified polyclonal antibody. PDE6C Antibody (Center) (ABIN653683) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
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Human Kaninchen Unkonjugiert IHC (p), WB Immunohistochemistry analysis in formalin fixed and paraffin embedded brain tissue reacted with PDE6C Antibody (Center) followed by peroxidase conjugation of the secondary antibody and DAB staining. Western blot analysis of PDE6C Antibody (Center) in mouse liver tissue lysates (35ug/lane). PDE6C (arrow) was detected using the purified Pab. 0.4 mL Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
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Human Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
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Human Maus Unkonjugiert ELISA, WB PDE6C polyclonal antibody (A01), Lot # 060116JC01 Western Blot analysis of PDE6C expression in HL-60 . Western Blot detection against Immunogen (36.89 KDa) . 50 μL Anmelden zum Anzeigen 7 bis 8 Tage
241,60 €
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Human Kaninchen Unkonjugiert IHC (p) PDE6C Antibody IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Anmelden zum Anzeigen 6 bis 8 Tage
538,22 €
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Human Kaninchen Unkonjugiert ELISA, IHC, WB   200 μL Anmelden zum Anzeigen 11 bis 14 Tage
941,11 €
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Human Kaninchen Unkonjugiert WB   100 μL Anmelden zum Anzeigen 11 bis 14 Tage
941,11 €
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Human Kaninchen Alkaline Phosphatase (AP) IHC, ELISA, WB   200 μL Anmelden zum Anzeigen 11 bis 14 Tage
1.203,02 €
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Human Kaninchen Biotin IHC, ELISA, WB   200 μL Anmelden zum Anzeigen 11 bis 14 Tage
1.203,02 €
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Human Kaninchen FITC IHC, ELISA, WB   200 μL Anmelden zum Anzeigen 11 bis 14 Tage
1.203,02 €
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PDE6C Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-PDE6C Antikörper

  1. Human Polyclonal PDE6C Primary Antibody für IHC (p), WB - ABIN653683 : Xu, Morris, Thapa, Ma, Michalakis, Biel, Baehr, Peshenko, Dizhoor, Ding: cGMP accumulation causes photoreceptor degeneration in CNG channel deficiency: evidence of cGMP cytotoxicity independently of enhanced CNG channel function. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2013 (PubMed)

Weitere Antikörper gegen PDE6C Interaktionspartner

Mouse (Murine) phosphodiesterase 6C, CGMP-Specific, Cone, alpha Prime (PDE6C) Interaktionspartner

  1. AIPL1 (zeige AIPL1 Antikörper)-mediated production of folded PDE6C is markedly elevated in the presence of the inhibitory Pgamma-subunit of PDE6.

  2. A comprehensive in vivo assessment of retinal morphology and function was performed in cpfl1 (cone photoreceptor function loss 1) mice to better define the disease process in this model of cone dystrophies.

  3. the spontaneous mouse mutant cpfl1 that features a lack of cone function and rapid degeneration of the cone photoreceptors represents a homologous mouse model for PDE6C associated achromatopsia.

Human phosphodiesterase 6C, CGMP-Specific, Cone, alpha Prime (PDE6C) Interaktionspartner

  1. A novel homozygous PDE6C mutation was identified as the cause of ACHM. In addition, we identified an OPN1SW (zeige OPN1SW Antikörper) mutation in the sibling with complete achromatopsia.

  2. The majority (n = 12) of patients were either homozygotes or compound heterozygotes for known achromatopsia alleles, two in CNGB3 (zeige CNGB3 Antikörper) (p.T383fsX and p.T296YfsX9) and three in CNGA3 (zeige CNGA3 Antikörper) (p.R283Q, p.R427C and p.L527R).

  3. analysis of amino acid residues responsible for the selectivity of tadalafil binding to two closely related phosphodiesterases, PDE5 (zeige PDE5A Antikörper) and PDE6

  4. Eleven different PDE6C mutations were found including two nonsense mutations, three mutations affecting transcript splicing as shown by minigene assays, one 1 bp-insertion and five missense mutations

  5. Homozygosity mapping reveals PDE6C mutations in patients with early-onset cone photoreceptor disorders.

  6. the identification of mutations in the PDE6C gene encoding the catalytic subunit of the cone photoreceptor phosphodiesterase as a cause of autosomal recessive achromatopsia was reported.

PDE6C Antigen-Profil

Protein Überblick

This gene encodes the alpha-prime subunit of cone phosphodiesterase, which is composed of a homodimer of two alpha-prime subunits and 3 smaller proteins of 11, 13, and 15 kDa. Mutations in this gene are associated with cone dystrophy type 4 (COD4).

Genbezeichner und Symbole assoziert mit PDE6C

  • phosphodiesterase 6C, cGMP-specific, cone, alpha prime (PDE6C) Antikörper
  • phosphodiesterase 6C, cGMP specific, cone, alpha prime (Pde6c) Antikörper
  • ACHM5 Antikörper
  • COD4 Antikörper
  • cpfl1 Antikörper
  • PDE6C Antikörper
  • PDEA2 Antikörper

Bezeichner auf Proteinebene für PDE6C

phosphodiesterase 6C, cGMP-specific, cone, alpha prime , cone cGMP phosphodiesterase-like , cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'-like , phosphodiesterase 6C, cGMP specific, cone, alpha prime , cyclic nucleotide phosphodiesterase 6c , cGMP phosphodiesterase 6C , cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' , PDE V-C1 , phosphodiesterase, cyclic GMP (cone receptor) , cone cGMP phosphodiesterase a'-subunit

GENE ID SPEZIES
486805 Canis lupus familiaris
700261 Macaca mulatta
740456 Pan troglodytes
100343836 Oryctolagus cuniculus
100444869 Pongo abelii
100480480 Ailuropoda melanoleuca
100527954 Cavia porcellus
100597030 Nomascus leucogenys
110855 Mus musculus
361752 Rattus norvegicus
5146 Homo sapiens
281975 Bos taurus
395834 Gallus gallus
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