anti-Wilms Tumor 1 Interacting Protein (WTIP) Antikörper

Adapter or scaffold protein which participates in the assembly of numerous protein complexes and is involved in several cellular processes such as cell fate determination, cytoskeletal organization, repression of gene transcription, cell-cell adhesion, cell differentiation, proliferation and migration. Zusätzlich bieten wir Ihnen WTIP Kits (5) und WTIP Proteine (2) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
Anti-Ratte WTIP WTIP 361552  
WTIP 126374 A6NIX2
Anti-Maus WTIP WTIP 101543 Q7TQJ8
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Showing 10 out of 23 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert IF, IHC (p), WB WTIP Antibody (C-term) (ABIN655782) western blot analysis in NCI-H460,WiDr cell line lysates (35 µg/lane). This demonstrates the WTIP antibody detected the WTIP protein (arrow). 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Kaninchen Unkonjugiert EIA, IF, IHC (p), WB Confocal immunofluorescent analysis of WTIP Antibody (C-term) with WiDr cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue). WTIP Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of WTIP Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. 0.4 mL Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
Details
Human Kaninchen Unkonjugiert IF, IHC (p), WB WTIP Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. Western blot analysis in NCI-H460,WiDr cell line lysates (35ug/lane). 400 μL Anmelden zum Anzeigen 6 bis 8 Tage
538,22 €
Details
Human Kaninchen Unkonjugiert ELISA, IF, IHC, WB   200 μL Anmelden zum Anzeigen 11 bis 14 Tage
941,11 €
Details
Human Kaninchen HRP ELISA, ICC, IF, IHC, WB   200 μL Anmelden zum Anzeigen 11 bis 14 Tage
1.203,02 €
Details
Human Kaninchen PE ELISA, ICC, IF, IHC, WB   200 μL Anmelden zum Anzeigen 11 bis 14 Tage
1.203,02 €
Details
Human Kaninchen Biotin ELISA, ICC, IF, IHC, WB   200 μL Anmelden zum Anzeigen 11 bis 14 Tage
1.203,02 €
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Human Kaninchen Alkaline Phosphatase (AP) ELISA, ICC, IF, IHC, WB   200 μL Anmelden zum Anzeigen 11 bis 14 Tage
1.203,02 €
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Human Kaninchen APC ELISA, ICC, IF, IHC, WB   200 μL Anmelden zum Anzeigen 11 bis 14 Tage
1.203,02 €
Details
Human Kaninchen FITC ELISA, ICC, IF, IHC, WB   200 μL Anmelden zum Anzeigen 11 bis 14 Tage
1.203,02 €
Details

WTIP Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Human
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Weitere Antikörper gegen WTIP Interaktionspartner

Human Wilms Tumor 1 Interacting Protein (WTIP) Interaktionspartner

  1. WTIP interacts with BRCA2 (zeige BRCA2 Antikörper) and might be responsible for BRCA2 (zeige BRCA2 Antikörper) centrosome localization in cervical cancer cell.

  2. Nck1 (zeige NCK1 Antikörper) and Nck2 (zeige NCK2 Antikörper) Interact with WTIP. Nck1 (zeige NCK1 Antikörper)/2 integrates nephrin (zeige NPHS1 Antikörper) with the Hippo kinase cascade through association with the adaptor protein WTIP.

  3. WTIP (zeige ASXL2 Antikörper)interacts with ASXL2 and blocks ASXL2-mediated activation of retin (zeige ASXL2 Antikörper)oic acid signaling.

  4. Wtip regulates the stable formation of cell adhesions to both extracellular matrix and neighboring cells and suggest that Wtip is necessary for normal glomerular filtration barrier function

  5. Report role of WTIP in regulating podocyte phenotype in chronic kidney disease.

  6. Full-length Ror2 (zeige ROR2 Antikörper) recruits Wtip to the cell membrane, a mutant involved in human disease fails to do so. Both genes and proteins show overlapping expression in the mouse embryo.

  7. WTIP is a member of the Ajuba (zeige AJUBA Antikörper) family of LIM (zeige PDLIM5 Antikörper)-domain containing proteins. Ajuba (zeige AJUBA Antikörper) LIM (zeige PDLIM5 Antikörper) proteins co-repress E-cadherin (zeige CDH1 Antikörper) expression through interaction with the SNAG domain of Snail (zeige SNAI1 Antikörper)/Slug (zeige SNAI2 Antikörper) and promote epithelial to mesenchymal differentiation in a Xenopus model.

  8. Stress signaling pathways initiate WTIP nuclear translocation, and the concomitant loss of WTIP from cell contacts changes podocyte morphology and dynamic actin assembly, suggesting a mechanism that transmits changes in podocyte morphology to the nucleus.

  9. WTIP monitors slit diaphragm protein assembly as part of a multiple protein complex, linking this specialized adhesion junction to the actin cytoskeleton, and shuttles into the nucleus after podocyte injury

Mouse (Murine) Wilms Tumor 1 Interacting Protein (WTIP) Interaktionspartner

  1. implicate Asxl1 (zeige ASXL1 Antikörper) in the maintenance of podocyte structure via its association with Wtip and in the regulation of WT1 (zeige WT1 Antikörper) signaling during early kidney development

  2. ASXL2 (zeige ASXL2 Antikörper) and WTIP are expressed in mouse embryonic epicardial cells. ASXL2 (zeige ASXL2 Antikörper) and WTIP participate in regulation of retinoic acid signaling during heart development.

  3. Dendrin is dispensable for the function of the normal glomerular filtration barrier, and it interacts with Wtip and Gadd45a (zeige GADD45A Antikörper).

  4. Wtip regulates the stable formation of cell adhesions to both extracellular matrix and neighboring cells and suggest that Wtip is necessary for normal glomerular filtration barrier function

  5. Podocyte injury induces nuclear translocation of WTIP via microtubule-dependent transport

  6. WTIP monitors slit diaphragm protein assembly as part of a multiple protein complex, linking this specialized adhesion junction to the actin cytoskeleton, and shuttles into the nucleus after podocyte injury

  7. Full-length Ror2 (zeige ROR2 Antikörper) recruits Wtip to the cell membrane, a mutant involved in human disease fails to do so.

WTIP Antigen-Profil

Protein Überblick

Adapter or scaffold protein which participates in the assembly of numerous protein complexes and is involved in several cellular processes such as cell fate determination, cytoskeletal organization, repression of gene transcription, cell-cell adhesion, cell differentiation, proliferation and migration. Positively regulates microRNA (miRNA)-mediated gene silencing. Negatively regulates Hippo signaling pathway and antagonizes phosphorylation of YAP1. Acts as a transcriptional corepressor for SNAI1 and SNAI2/SLUG-dependent repression of E-cadherin transcription. Acts as a hypoxic regulator by bridging an association between the prolyl hydroxylases and VHL enabling efficient degradation of HIF1A. May monitor slit diaphragm protein assembly, a specialized adherens junction characteristic of podocytes. In case of podocyte injury, it shuttles into the nucleus and acts as a transcription regulator that represses WT1- dependent transcription regulation, thereby translating changes in slit diaphragm structure into altered gene expression and a less differentiated phenotype.

Genbezeichner und Symbole assoziert mit WTIP

  • Wilms tumor 1 interacting protein (Wtip) Antikörper
  • Wilms tumor 1 interacting protein (WTIP) Antikörper
  • Wilms tumor 1 interacting protein (wtip) Antikörper
  • WT1-interacting protein (Wtip) Antikörper
  • RGD1306411 Antikörper
  • si:ch211-79l17.3 Antikörper

Bezeichner auf Proteinebene für WTIP

WT1-interacting protein , Wilms tumor protein 1-interacting protein , Wilms tumor protein 1-interacting protein homolog , WT1-interacting protein homolog , Wilms tumor 1 interacting protein , xWtip

GENE ID SPEZIES
361552 Rattus norvegicus
505059 Bos taurus
566046 Danio rerio
747259 Pan troglodytes
769595 Gallus gallus
126374 Homo sapiens
100127345 Xenopus laevis
101543 Mus musculus
Ausgewählte Anbieter für anti-WTIP (WTIP) Antikörper
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