anti-Vacuolar Protein Sorting 13 Homolog A (S. Cerevisiae) (VPS13A) Antikörper

The protein encoded by VPS13A may control steps in the cycling of proteins through the trans-Golgi network to endosomes, lysosomes and the plasma membrane.

Alle Antikörper anzeigen Gen GeneID UniProt
Anti-Ratte VPS13A VPS13A 309243  
VPS13A 23230 Q96RL7
Anti-Maus VPS13A VPS13A 271564 Q5H8C4
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Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), WB Immunohistochemistry-Paraffin: Chorein Antibody [NBP1-85642] - Staining of human duodenum shows strong granular cytoplasmic positivity in glandular cells. Immunocytochemistry/Immunofluorescence: Chorein Antibody [NBP1-85642] - Immunofluorescent staining of human cell line U-2 OS shows positivity in mitochondria. 0.1 mL Anmelden zum Anzeigen 5 bis 8 Tage
335,00 €
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Human Kaninchen Unkonjugiert IHC, IHC (p), IP Immunohistochemistry: Chorein Antibody [NBP1-85641] - Staining of human testis shows strong cytoplasmic positivity in cells of seminiferus ducts. 0.1 mL Anmelden zum Anzeigen 5 bis 8 Tage
335,00 €
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Human Kaninchen Unkonjugiert EIA, IHC (fro), WB   0.2 mL Anmelden zum Anzeigen 7 bis 9 Tage
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Human Kaninchen Unkonjugiert IHC (p), IHC, WB   0.2 mL Anmelden zum Anzeigen 2 bis 4 Tage
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Human Kaninchen Unkonjugiert ELISA, IF, WB   100 μL Anmelden zum Anzeigen 2 bis 3 Tage
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Human Kaninchen Unkonjugiert IHC, WB   100 μL Anmelden zum Anzeigen 11 bis 14 Tage
653,02 €
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Human Kaninchen Unkonjugiert IHC (p)   100 μL Anmelden zum Anzeigen 7 bis 8 Tage
480,00 €
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VPS13A Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität
Human , ,


Am meisten referenzierte anti-Vacuolar Protein Sorting 13 Homolog A (S. Cerevisiae) Antikörper

  1. Human Polyclonal VPS13A Primary Antibody für ELISA, IF - ABIN347141 : Saiki, Sakai, Murata, Saiki, Nakanishi, Kitagawa, Kaito, Gondo, Kumamoto, Matsui, Hattori, Hirose: Primary skeletal muscle involvement in chorea-acanthocytosis. in Movement disorders : official journal of the Movement Disorder Society 2007 (PubMed)

  2. Human Polyclonal VPS13A Primary Antibody für ICC, IF - ABIN4298102 : Morisaki, Yashiro, Kakehashi, Inagaki, Kinoshita, Fukuoka, Kasashima, Masuda, Sakurai, Kubo, Muguruma, Ohira, Wanibuchi, Hirakawa: Comparative proteomics analysis of gastric cancer stem cells. in PLoS ONE 2014 (PubMed)

  3. Human Polyclonal VPS13A Primary Antibody für IHC, IHC (p) - ABIN4298101 : Sasaki, Nakamura, Kodama, Urata, Shiokawa, Hayashi, Sano: Chorein interacts with α-tubulin and histone deacetylase 6, and overexpression preserves cell viability during nutrient deprivation in human embryonic kidney 293 cells. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2016 (PubMed)

Weitere Antikörper gegen Vacuolar Protein Sorting 13 Homolog A (S. Cerevisiae) Interaktionspartner

Human Vacuolar Protein Sorting 13 Homolog A (S. Cerevisiae) (VPS13A) Interaktionspartner

  1. These results suggest that PI3P regulates the functioning of Vps13, both in protein trafficking and actin cytoskeleton organization. Attenuation of PI3P-binding ability in the mutant hVps13A protein may be one of the reasons for its mislocalization and disrupted function in cells of patients suffering from chorea-acanthocytosis .

  2. Chorein is a stimulator of Orai1 (zeige ORAI1 Antikörper) expression and thus of store operated Ca2 (zeige CA2 Antikörper)+ entry.

  3. Patients with chorea-acanthocytosis carrying a VPS13A mutation present with focal, treatment-resistant seizures.

  4. Defective chorein is accompanied by significant structural disorganization of all cytoskeletal structures.

  5. VPS13A-depleted cells showed accumulation of autophagic markers and impaired autophagic flux

  6. Chorein is expressed in various cancer cells. In cells with high chorein expression levels chorein silencing promotes apoptotic cell death, an effect paralleled by down-regulation of PI-3K activity and BCL-2 (zeige BCL2 Antikörper)/Bax (zeige BAX Antikörper) expression ratio.

  7. Discovery of new mutations may clarify the pathogenic roles of chorein in chorea-acanthocytosis as well as in the retina

  8. chorein interacts with beta-adducin (zeige ADD2 Antikörper) and beta-actin (zeige ACTB Antikörper).

  9. Data indicate functions of chorein, i.e., regulation of secretion and aggregation of blood platelets.

  10. This study demonistrated that neuroacanthocytosis disorders has heterozygotes for mutations in the VPS13A gene.

Mouse (Murine) Vacuolar Protein Sorting 13 Homolog A (S. Cerevisiae) (VPS13A) Interaktionspartner

  1. chorein interacts with beta-adducin (zeige ADD2 Antikörper) and beta-actin (zeige ACTB Antikörper).

  2. Mouse CHAC cDNA sequence and the exon-intron structures of the CHAC disease gene are identified and a CHAC model mouse produced by a gene-targeting technique.

  3. Brain-specific (zeige CALY Antikörper) variants of VPS13A may be involved in the brain-specific (zeige CALY Antikörper) pathology of chorea-acanthocytosis.

Vacuolar Protein Sorting 13 Homolog A (S. Cerevisiae) (VPS13A) Antigen-Profil

Protein Überblick

The protein encoded by this gene may control steps in the cycling of proteins through the trans-Golgi network to endosomes, lysosomes and the plasma membrane. Mutations in this gene cause the autosomal recessive disorder, chorea-acanthocytosis. Alternative splicing of this gene results in multiple transcript variants.

Genbezeichner und Symbole assoziert mit VPS13A

  • vacuolar protein sorting 13 homolog A (S. cerevisiae) (Vps13a) Antikörper
  • chorein (EHI_067970) Antikörper
  • Chorein (GL50803_87358) Antikörper
  • vacuolar protein sorting 13 homolog A (S. cerevisiae) (VPS13A) Antikörper
  • vacuolar protein sorting 13A (yeast) (Vps13a) Antikörper
  • 4930425F11 Antikörper
  • 4930516E05Rik Antikörper
  • 4930543C13Rik Antikörper
  • 9930023P20 Antikörper
  • Chac Antikörper
  • Chorein Antikörper
  • D330038K10Rik Antikörper
  • mKIAA0986 Antikörper
  • RGD1311340 Antikörper

Bezeichner auf Proteinebene für VPS13A

vacuolar protein sorting 13 homolog A , chorein , vacuolar protein sorting 13A , Chorein , vacuolar protein sorting 13 homolog A (S. cerevisiae) , chorea-acanthocytosis protein , vacuolar protein sorting-associated protein 13A , chorea-acanthocytosis protein homolog , hypothetical protein

GENE ID SPEZIES
309243 Rattus norvegicus
3411085 Entamoeba histolytica HM-1:IMSS
5700841 Giardia lamblia ATCC 50803
464538 Pan troglodytes
23230 Homo sapiens
271564 Mus musculus
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