anti-Ubiquitin Specific Peptidase 15 (USP15) Antikörper

USP15 encodes a member of the ubiquitin specific protease (USP) family of deubiquitinating enzymes. Zusätzlich bieten wir Ihnen USP15 Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
USP15 9958 Q9Y4E8
USP15 14479 Q8R5H1
USP15 171329  
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Top anti-USP15 Antikörper auf antikoerper-online.de

Showing 10 out of 90 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert IF, WB <b>WB Suggested Anti-USP15 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>Jurkat cell lysate Immunofluorescence Sample Type: A549&HEK293T cellsPrimary Dilution: 1:500 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert WB USP15 Antibody (N-term) (ABIN658273) western blot analysis in mouse cerebellum tissue lysates (35 µg/lane). This demonstrates the USP15 antibody detected the USP15 protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), IP, WB Western Blot: USP15 Antibody [ABIN2582840] - Whole cell lysate (50 ug) from NIH3T3, TCMK-1, 4T1, CT26.WT, and rat C6 cells. 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$556.31
Details
Human Ziege Unkonjugiert IHC, ELISA, WB   100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$358.02
Details
Human Ziege Unkonjugiert IHC (p), IHC, ELISA Immunohistochemistry-Paraffin: USP15 Antibody [ABIN249918] - 3.8ug/ml staining of paraffin embedded Human Liver. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$485.88
Details
Human Kaninchen Unkonjugiert EIA, WB 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Maus Unkonjugiert IF, WB 0.1 mg Anmelden zum Anzeigen 3 bis 4 Tage
$601.76
Details
Human Kaninchen Unkonjugiert WB The anti-USP15 Pab (ABIN388904) is used in Western blot to detect USP15 in mouse brain tissue lysate. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC (p), WB WB Image Sample (30 ug of whole cell lysate) A: NIH-3T3 B: JC C: BCL-1 7.5% SDS PAGE antibody diluted at 1:1000 ICC/IF Image Immunofluorescence analysis of paraformaldehyde-fixed A431, using USP15, antibody at 1:200 dilution. 100 μL Anmelden zum Anzeigen 1 bis 2 Tage
$358.60
Details
Rind (Kuh) Ziege Unkonjugiert EIA, IHC (p) Staining of paraffin embedded Human Liver using USP15 antibody at 2 µg/ml. Steamed antigen retrieval with citrate buffer pH 6, HRP-staining. 0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details

USP15 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-USP15 Antikörper

  1. Human Monoclonal USP15 Primary Antibody für IF, ELISA - ABIN564282 : Schweitzer, Bozko, Dubiel, Naumann: CSN controls NF-kappaB by deubiquitinylation of IkappaBalpha. in The EMBO journal 2007 (PubMed)
    Show all 9 Pubmed References

  2. Human Polyclonal USP15 Primary Antibody für ICC, IF - ABIN258284 : Isumi, Hirata, Saitoh, Miyakawa, Murakami, Kudoh, Doi, Ishibashi, Nakajima: Transgenic overexpression of USP15 in the heart induces cardiac remodeling in mice. in Biochemical and biophysical research communications 2011 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal USP15 Primary Antibody für IHC (p), IHC - ABIN249918 : Baker, Wang, Woollatt, White, Sutherland et al.: Identification, functional characterization, and chromosomal localization of USP15, a novel human ubiquitin-specific protease related to the UNP oncoprotein, and a systematic nomenclature for human ... in Genomics 1999 (PubMed)

  4. Human Monoclonal USP15 Primary Antibody für IF, WB - ABIN2477039 : Miyauchi, Kato, Tokunaga, Iwai: The COP9/signalosome increases the efficiency of von Hippel-Lindau protein ubiquitin ligase-mediated hypoxia-inducible factor-alpha ubiquitination. in The Journal of biological chemistry 2008 (PubMed)

Weitere Antikörper gegen USP15 Interaktionspartner

Human Ubiquitin Specific Peptidase 15 (USP15) Interaktionspartner

  1. these data indicate that Nef and USP15 are vital in regulating degradation of viral and cellular proteins and thus HIV-1 replication, and specific degradation of viral, not cellular proteins.

  2. We show that PRP31 (zeige PRPF31 Antikörper), a component of U4 snRNP (zeige LSM2 Antikörper), is modified with K63-linked ubiquitin chains by the PRP19 (zeige PRPF19 Antikörper) complex and deubiquitinated by USP15 and its substrate targeting factor SART3 (zeige SART3 Antikörper). USP15SART3 makes a complex with USP4 (zeige USP4 Antikörper) and this ternary complex serves as a platform to deubiquitinate PRP31 (zeige PRPF31 Antikörper) and PRP3 (zeige CLCA4 Antikörper)

  3. TGF-b promotes the translation of USP15 through activation of mammalian target of rapamycin (zeige FRAP1 Antikörper) by the phosphoinositide 3-kinase/AKT (zeige AKT1 Antikörper) pathway. Upregulation of USP15 translation links the crosstalk between TGF-beta (zeige TGFB1 Antikörper) signaling and p53 (zeige TP53 Antikörper) stability, allowing this cytokine to have a critical role in cancer progression.

  4. We concluded that USP15 attenuates IGF-I (zeige IGF1 Antikörper) signaling by antagonizing Nedd4 (zeige NEDD4 Antikörper)-induced IRS-2 (zeige IRS2 Antikörper) ubiquitination.

  5. These results uncover a new regulatory mechanism that USP15 activates Nrf1 (zeige NFE2L1 Antikörper) against the beta-TrCP (zeige BTRC Antikörper) inhibition to maintain proteostasis.

  6. Study identified USP15 as having recurrent de novo loss of function mutations and discovered evidence supporting two other known genes with recurrent de novo variants (FOXP1 (zeige FOXP1 Antikörper) and KDM5B (zeige KDM5B Antikörper)).

  7. crystal structures of SART3 (zeige SART3 Antikörper) in the apo (zeige C9orf3 Antikörper)-form and in complex with the DUSP (zeige DUSP5 Antikörper)-UBL domain of USP15 at 2.0 and 3.0 A, respectively. Structural analysis reveals SART3 (zeige SART3 Antikörper) contains 12 half-a-tetratricopeptide (HAT (zeige MGEA5 Antikörper)) repeats, organized into two subdomains, HAT (zeige MGEA5 Antikörper)-N and HAT (zeige MGEA5 Antikörper)-C. SART3 (zeige SART3 Antikörper) dimerizes through the concave surface of HAT (zeige MGEA5 Antikörper)-C, whereas the HAT (zeige MGEA5 Antikörper)-C convex surface binds USP15 in a novel bipartite mode.

  8. SMURF2 (zeige SMURF2 Antikörper) is a critical target of USP15 in the TGF-beta (zeige TGFB1 Antikörper) signaling pathway.

  9. our data demonstrate that USP15 acts as a negative regulator of RIG-I (zeige DDX58 Antikörper) signaling via DUB-dependent and independent mechanisms.

  10. These data identify USP15 as an antagonist of Parkin (zeige PARK2 Antikörper) and suggest that USP15 inhibition could be a therapeutic strategy for PD cases caused by reduced Parkin (zeige PARK2 Antikörper) levels.

Mouse (Murine) Ubiquitin Specific Peptidase 15 (USP15) Interaktionspartner

  1. In hematopoietic cells and in resident brain cells, USP15 was coexpressed with, and functionally acted together with the E3 ubiquitin ligase (zeige MUL1 Antikörper) TRIM25 (zeige TRIM25 Antikörper) to positively regulate type I interferon (zeige IFNA Antikörper) responses and to promote pathogenesis during neuroinflammation.

  2. T cell intrinsic USP15 deficiency causes excessive production of IFN-gamma (zeige IFNG Antikörper), which promotes an immunosuppressive tumor microenvironment during MCA (zeige RSPH1 Antikörper)-induced primary tumorigenesis.

  3. Both mouse and human have 22 exons with identical splice sites and an exon/intron structure identical to the mouse Usp4 (zeige USP4 Antikörper) gene.

USP15 Antigen-Profil

Protein Überblick

This gene encodes a member of the ubiquitin specific protease (USP) family of deubiquitinating enzymes. USP enzymes play critical roles in ubiquitin-dependent processes through polyubiquitin chain disassembly and hydrolysis of ubiquitin-substrate bonds. The encoded protein associates with the COP9 signalosome, and also plays a role in transforming growth factor beta signalling through deubiquitination of receptor-activated SMAD transcription factors. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 2.

Genbezeichner und Symbole assoziert mit USP15

  • ubiquitin specific peptidase 15 (USP15) Antikörper
  • universal stress protein UspA (RR_RS05795) Antikörper
  • ubiquitin carboxyl-terminal hydrolase 15 (LOC100090554) Antikörper
  • ubiquitin specific peptidase 15 (usp15) Antikörper
  • ubiquitin specific peptidase 15 (Usp15) Antikörper
  • 4921514G19Rik Antikörper
  • AI327321 Antikörper
  • E430033I05Rik Antikörper
  • Gcap18 Antikörper
  • mKIAA0529 Antikörper
  • Ubp109 Antikörper
  • UNP Antikörper
  • UNPH-2 Antikörper
  • UNPH4 Antikörper
  • USP15 Antikörper

Bezeichner auf Proteinebene für USP15

ubiquitin specific peptidase 15 , universal stress protein , ubiquitin carboxyl-terminal hydrolase 15-like , ubiquitin carboxyl-terminal hydrolase 15 , ubiquitin specific protease 15 , ubiquitous nuclear protein , Deubiquitinating enzyme 15 , Ubiquitin thioesterase 15 , Ubiquitin-specific-processing protease 15 , deubiquitinating enzyme 15 , ubiquitin thioesterase 15 , ubiquitin-specific-processing protease 15 , ubiquitin thiolesterase 15 , granule cell antiserum positive 18 , deubiquitinating enzyme Ubp109 , ubiquitin carboxyl-terminal hydrolase of 109 kDa

GENE ID SPEZIES
716793 Macaca mulatta
3128959 Haloarcula marismortui ATCC 43049
100090554 Ornithorhynchus anatinus
100464241 Ailuropoda melanoleuca
395644 Gallus gallus
452035 Pan troglodytes
100012616 Monodelphis domestica
100055857 Equus caballus
100158604 Xenopus (Silurana) tropicalis
100224751 Taeniopygia guttata
100356438 Oryctolagus cuniculus
100412030 Callithrix jacchus
100454837 Pongo abelii
100542201 Meleagris gallopavo
100554748 Anolis carolinensis
100586852 Nomascus leucogenys
538284 Bos taurus
9958 Homo sapiens
14479 Mus musculus
474424 Canis lupus familiaris
100524085 Sus scrofa
171329 Rattus norvegicus
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