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USP15 Produkte

(Ubiquitin Specific Peptidase 15 (USP15))

Kategorien

This gene encodes a member of the ubiquitin specific protease (USP) family of deubiquitinating enzymes. USP enzymes play critical roles in ubiquitin-dependent processes through polyubiquitin chain disassembly and hydrolysis of ubiquitin-substrate bonds. The encoded protein associates with the COP9 signalosome, and also plays a role in transforming growth factor beta signalling through deubiquitination of receptor-activated SMAD transcription factors. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 2. [provided by RefSeq, Nov 2011].

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Ausgewählte USP15 Kategorien

USP15 Antikörper

High quality antibodies with extensive validation data.

USP15 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene USP15 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA, IF
Validierungen
  • (9)
  • (5)
Kat. Nr. ABIN564282
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation WB, IF, IHC (p)
Validierungen
  • (5)
Kat. Nr. ABIN388904
Menge 400 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IF, IHC (p), ICC
Validierungen
  • (4)
Kat. Nr. ABIN2855881
Menge 100 μL
Datenblatt Datenblatt

Empfohlene USP15 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6222175
Menge 96 tests
Datenblatt Datenblatt

Empfohlene USP15 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7125589
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1324756
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3096215
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren USP15 Produkten

Oikonomaki, Bady, Hegi: "Ubiquitin Specific Peptidase 15 (USP15) suppresses glioblastoma cell growth via stabilization of HECTD1 E3 ligase attenuating WNT pathway activity." in: Oncotarget, Vol. 8, Issue 66, pp. 110490-110502, (2018) (PubMed).

Zhang, Wang, Zhong, Luo, Shang, Liu, Chen, Fang, Xiao: "Ubiquitin-specific Protease 15 Negatively Regulates Virus-induced Type I Interferon Signaling via Catalytically-dependent and -independent Mechanisms." in: Scientific reports, Vol. 5, pp. 11220, (2016) (PubMed).

Pauli, Chan, Davis, Gableske, Wang, Feister, Gack: "The ubiquitin-specific protease USP15 promotes RIG-I-mediated antiviral signaling by deubiquitylating TRIM25." in: Science signaling, Vol. 7, Issue 307, pp. ra3, (2014) (PubMed).

García-Caballero, Gadotti, Stemkowski, Weiss, Souza, Hodgkinson, Bladen, Chen, Hamid, Pizzoccaro, Deage, François, Bourinet, Zamponi: "The deubiquitinating enzyme USP5 modulates neuropathic and inflammatory pain by enhancing Cav3.2 channel activity." in: Neuron, Vol. 83, Issue 5, pp. 1144-58, (2014) (PubMed).

Cornelissen, Haddad, Wauters, Van Humbeeck, Mandemakers, Koentjoro, Sue, Gevaert, De Strooper, Verstreken, Vandenberghe: "The deubiquitinase USP15 antagonizes Parkin-mediated mitochondrial ubiquitination and mitophagy." in: Human molecular genetics, Vol. 23, Issue 19, pp. 5227-42, (2014) (PubMed).

Goncharov, Niessen, de Almagro, Izrael-Tomasevic, Fedorova, Varfolomeev, Arnott, Deshayes, Kirkpatrick, Vucic: "OTUB1 modulates c-IAP1 stability to regulate signalling pathways." in: The EMBO journal, Vol. 32, Issue 8, pp. 1103-14, (2013) (PubMed).

Isumi, Hirata, Saitoh, Miyakawa, Murakami, Kudoh, Doi, Ishibashi, Nakajima: "Transgenic overexpression of USP15 in the heart induces cardiac remodeling in mice." in: Biochemical and biophysical research communications, Vol. 405, Issue 2, pp. 216-21, (2011) (PubMed).

Fernandez-Sanchez, Sechet, Margottin-Goguet, Rogge, Bianchi: "The human COP9 signalosome protects ubiquitin-conjugating enzyme 3 (UBC3/Cdc34) from beta-transducin repeat-containing protein (betaTrCP)-mediated degradation." in: The Journal of biological chemistry, Vol. 285, Issue 23, pp. 17390-7, (2010) (PubMed).

Vos, Altreuter, White, Howley: "The ubiquitin-specific peptidase USP15 regulates human papillomavirus type 16 E6 protein stability." in: Journal of virology, Vol. 83, Issue 17, pp. 8885-92, (2009) (PubMed).

Xu, Takanashi, Oikawa, Tanaka, Nishi, Isaka, Kudo, Kuroda: "USP15 plays an essential role for caspase-3 activation during Paclitaxel-induced apoptosis." in: Biochemical and biophysical research communications, Vol. 388, Issue 2, pp. 366-71, (2009) (PubMed).

Synonyme und alternative Namen zu USP15

ubiquitin specific peptidase 15 (USP15), universal stress protein UspA (RR_RS05795), ubiquitin carboxyl-terminal hydrolase 15 (LOC100090554), ubiquitin specific peptidase 15 (usp15), ubiquitin specific peptidase 15 (Usp15), 4921514G19Rik, AI327321, E430033I05Rik, Gcap18, mKIAA0529, Ubp109, UNP, UNPH-2, UNPH4, USP15

Bezeichner auf Proteinebene für USP15

  • ubiquitin specific peptidase 15
  • universal stress protein
  • ubiquitin carboxyl-terminal hydrolase 15-like
  • ubiquitin carboxyl-terminal hydrolase 15
  • ubiquitin specific protease 15
  • ubiquitous nuclear protein
  • Deubiquitinating enzyme 15
  • Ubiquitin thioesterase 15
  • Ubiquitin-specific-processing protease 15
  • deubiquitinating enzyme 15
  • ubiquitin thioesterase 15
  • ubiquitin-specific-processing protease 15
  • ubiquitin thiolesterase 15
  • granule cell antiserum positive 18
  • deubiquitinating enzyme Ubp109
  • ubiquitin carboxyl-terminal hydrolase of 109 kDa
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