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anti-Tumor Protein P63 (TP63) Antikörper

TP63 encodes a member of the p53 family of transcription factors. Zusätzlich bieten wir Ihnen p63 Kits (27) und p63 Proteine (8) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
TP63 21454 P11983
TP63 8626 Q9H3D4
TP63 246334 Q9JJP6
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Top anti-p63 Antikörper auf

Showing 10 out of 69 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert WB TP63 Antibody (C-term) (ABIN657886) western blot analysis in MDA-MB231 cell line lysates (35 µg/lane). This demonstrates the TP63 antibody detected the TP63 protein (arrow). 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Human Kaninchen Unkonjugiert ICC, IHC (p), WB Anti-p63 antibody, IHC(P) IHC(P): Human Lung Cancer Tissue Anti-p63 antibody, Western blotting Lane 1: HELA Cell Lysate Lane 2: SMMC Cell Lysate Lane 3: COLO320 Cell Lysate Lane 4: A549 Cell Lysate Lane 5: SGC Cell Lysate 100 μg Anmelden zum Anzeigen 8 bis 11 Tage
298,57 €
Human Maus Unkonjugiert IHC (p) Detection of p63 protein in nucleus of epidermis stained with anti-p63 antibody 10 mL Anmelden zum Anzeigen 1 bis 2 Tage
330,00 €
Human Kaninchen Unkonjugiert ICC, IHC (p), WB Anti-p63 Picoband antibody,  IHC(P): Human Oesophagus Squama Cancer Tissue Anti-p63 Picoband antibody,  All lanes: Anti P63  at 0.5ug/ml WB: Recombinant Human P63 Protein 0.5ng Predicted bind size: 39KD Observed bind size: 39KD 100 μg Anmelden zum Anzeigen 8 bis 11 Tage
340,48 €
Human Maus Unkonjugiert IHC, WB 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
366,67 €
Human Ziege Unkonjugiert ELISA, WB 0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
505,48 €
Human Maus Unkonjugiert WB TP63 Antibody (Ascites) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the TP63 antibody detected the TP63 protein (arrow). 0.1 mL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Human Kaninchen Unkonjugiert IHC, WB Immunohistochemistry of paraffin-embedded rat kidney using TP63 antibody at dilution of 1:100 (x400 lens). 100 μL Anmelden zum Anzeigen 12 Days
261,90 €
Human Maus Unkonjugiert ELISA, WB Detection limit for recombinant GST tagged TP73L is approximately 0.3 ng/mL as a capture antibody. 0.1 mg Anmelden zum Anzeigen 12 bis 16 Tage
454,76 €
Human Maus Unkonjugiert ELISA, IHC, WB   100 μL Anmelden zum Anzeigen 12 bis 16 Tage
550,00 €

TP63 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Mouse (Murine) ,
Human , , ,
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Rat (Rattus) ,

Am meisten referenzierte anti-p63 Antikörper

  1. Human Monoclonal p63 Primary Antibody für IHC (p) - ABIN93812 : Yang, Kaghad, Wang, Gillett, Fleming, Dötsch, Andrews, Caput, McKeon: p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities. in Molecular cell 1998 (PubMed)
    Zeige alle 4 Referenzen für ABIN93812

  2. Human Polyclonal p63 Primary Antibody für WB - ABIN657886 : Miki, Kubo, Takahashi, Yoon, Kim, Lee, Zo, Lee, Hosono, Morizono, Tsunoda, Kamatani, Chayama, Takahashi, Inazawa, Nakamura, Daigo: Variation in TP63 is associated with lung adenocarcinoma susceptibility in Japanese and Korean populations. in Nature genetics 2010 (PubMed)
    Zeige alle 2 Referenzen für ABIN657886

  3. Human Monoclonal p63 Primary Antibody für IHC, WB - ABIN2673817 : Zhang, Wei, Dang, Xie, Zhong, Ma, Chen: Primary urinary bladder adenosquamous carcinoma complicated with lower limb deep venous thromboses: a case report. in International journal of clinical and experimental pathology 2015 (PubMed)

Weitere Antikörper gegen p63 Interaktionspartner

Horse (Equine) Tumor Protein P63 (TP63) Interaktionspartner

  1. p63 expression was significantly lower in the chronic laminitic hoof than in that of control horses

Mouse (Murine) Tumor Protein P63 (TP63) Interaktionspartner

  1. IL-6 (zeige IL6 Antikörper)/P-STAT3 (zeige STAT3 Antikörper) activation influences p63 (zeige CKAP4 Antikörper) isoform expression in healing wounds, which may contribute to wound-induced hair follicle neogenesis.

  2. In vivo inhibition of both p63 (zeige CKAP4 Antikörper) and p73 (zeige ARHGAP24 Antikörper) in combination accelerates tumor regression and increases survival of p53 (zeige TP53 Antikörper)-deficient mice.

  3. Data show that T-complex protein 1 (TCP-1) may be a crucial downstream molecule of purinergic receptor P2X 7 (zeige P2RX7 Antikörper) (P2X7R (zeige P2RX7 Antikörper)) and plays a role in lymphoid neoplasm metastasis.

  4. The data presented here reveal an additional level of interplay between CCT (zeige FLVCR2 Antikörper) and actin mediated via gelsolin (zeige GSN Antikörper), suggesting that CCT (zeige FLVCR2 Antikörper) may influence processes depending on gelsolin (zeige GSN Antikörper) activity, such as cell motility.

  5. p63 (zeige CKAP4 Antikörper) expression could be detected as early as E8.5 in mouse embryos preceding epidermal commitment.

  6. Lack of embryonic brain development was found in p63 (zeige CKAP4 Antikörper)-knockout mice.

  7. Data show that the transcription factor protein (zeige SSRP1 Antikörper) 63 (p63 (zeige CKAP4 Antikörper)) is a master regulator of the transition from the reserve to the active stem cell pool in the epithelium.

  8. Pvrl1 (zeige PVRL1 Antikörper) is a bona fide target gene of the transcription factor p63 (zeige CKAP4 Antikörper), whereas Pvrl4 (zeige PVRL4 Antikörper) regulation is linked to epidermal differentiation and is under Irf6 (zeige IRF6 Antikörper)

  9. Oocyte-specific inactivation of Omcg1 leads to DNA damage and c-Abl/TAp63-dependent oocyte death associated with dramatic remodeling of ovarian somatic cells.

  10. Some miRs control p63 (zeige CKAP4 Antikörper) expression, and p63 (zeige CKAP4 Antikörper) regulates the miR (zeige MLXIP Antikörper) expression profile in the epidermis. p63 (zeige CKAP4 Antikörper) controls miR (zeige MLXIP Antikörper) expression at different levels.

Human Tumor Protein P63 (TP63) Interaktionspartner

  1. These results suggest that whereas GATA-3 and uroplakin II may be most useful in the diagnosis of urothelial carcinoma metastasis, p40 may be additionally suited as a prognostic marker.

  2. TP63 gene mutation is involved in the familial ADULT syndrome diagnosed in a family.

  3. A large number of giant cell tumors of bone (96.8%) are positive for p63 (zeige RPE65 Antikörper), which is considerably more than any other giant cell-rich lesion.

  4. The expression of CK5 (zeige KRT5 Antikörper)/6 and of P63 (zeige RPE65 Antikörper) suggests a squamous differentiation including in the basaloid thyroid lymphoepithelial complexes

  5. DeltaNp63alpha is a vital epithelial-mesenchymal transition repressor in cervical squamous cell carcinoma cells. SCC (zeige CYP11A1 Antikörper) patients with low DeltaNp63alpha expression and high EMT (zeige ITK Antikörper) level show more frequent metastasis and recurrence as well as reduced overall survival. The miR (zeige MLXIP Antikörper)-205/ZEB1 (zeige ZEB1 Antikörper) axis is involved in the inhibition effect of DeltaNp63alpha on EMT (zeige ITK Antikörper).

  6. Immunocytochemistry using this antibody cocktail comprises five antibodies recognising p63 (zeige RPE65 Antikörper), and cytokeratins ( 7, 18, 5 and 14) showed good sensitivity and specificity for diagnosing breast cancers. Thus, this method is useful for mammary cytology using FNA

  7. HCC1806 cells endogenously express p63 (zeige RPE65 Antikörper), mainly as the DeltaNp63alpha isoform. Endogenous p63 (zeige RPE65 Antikörper) is required to suppress the expression of luminal markers and maintain the basal epithelial phenotype, but p63 (zeige RPE65 Antikörper) loss is insufficient to induce full luminal-type differentiation. p63 (zeige RPE65 Antikörper) exerts multiple pro-oncogenic effects on cell differentiation, proliferation and adhesion in basal-like breast cancers.

  8. The findings suggest that miR (zeige MLXIP Antikörper)-203 is a tumor suppressor that plays an important role in inhibiting the occurrence of Kazakh esophageal squamous cell carcinoma in China via regulating the expression of p63 (zeige RPE65 Antikörper).

  9. Single-cell pattern is frequently a component of morpheaform basal cell carcinoma. TP63/cytokeratin (zeige KRT4 Antikörper) staining may aid in identification of these tumor cells.

  10. Although preliminary, the expression levels of DeltaNp63 mRNA and miR (zeige MLXIP Antikörper)-203 seem to be promising for cervical cancer screening. In addition, positive correlation between miR (zeige MLXIP Antikörper)-203 and DeltaNp63 expression suggests the possible existence of some indirect pathways

Zebrafish Tumor Protein P63 (TP63) Interaktionspartner

  1. they unravel essential roles of TAp63 and p53 (zeige TP53 Antikörper) to promote both keratinocyte proliferation and their terminal differentiation by promoting Notch (zeige NOTCH1 Antikörper) signalling and caspase 3 (zeige CASP3 Antikörper) activity.

  2. the p63 transcription factor is upregulated to initiate this apoptotic pathway and directly activates puma (zeige BBC3 Antikörper) transcription in response to ER stress.

  3. Early zebrafish embryos express a dominant-negative form of p63 (DeltaNp63), which accumulates in the nucleus just as epidermal growth begins. (p63)

  4. DeltaNp63 expression blocks neural development and promotes nonneural development, even in the absence of Bmp signaling. (DeltaNp63)

  5. rps19 (zeige RPS19 Antikörper)-deficient phenotype is mediated by dysregulation of deltaNp63 and p53 (zeige TP53 Antikörper) and results in hematopoietic and developmental abnormalities resembling Diamond-Blackfan anemia

Xenopus laevis Tumor Protein P63 (TP63) Interaktionspartner

  1. Data indicate that pluripotency genes sox2, p63 and oct60 are upregulated early during the process of lens regeneration.

  2. The results suggest that DeltaNp63 is an essential gene in early epidermal specification under the control of BMP4 (zeige BMP4 Antikörper).

  3. The role of p63 as a negative Wnt (zeige WNT2 Antikörper)-regulator thus matches with the frequently observed downregulation of p63 during tumor progression, when cancer cells adopt a more mesenchymal, invasive phenotype.

p63 (TP63) Antigen-Profil

Protein Überblick

This gene encodes a member of the p53 family of transcription factors. An animal model, p63 -/- mice, has been useful in defining the role this protein plays in the development and maintenance of stratified epithelial tissues. p63 -/- mice have several developmental defects which include the lack of limbs and other tissues, such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3)\; split-hand/foot malformation 4 (SHFM4)\; ankyloblepharon-ectodermal defects-cleft lip/palate\; ADULT syndrome (acro-dermato-ungual-lacrimal-tooth)\; limb-mammary syndrome\; Rap-Hodgkin syndrome (RHS)\; and orofacial cleft 8. Both alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different proteins. Many transcripts encoding different proteins have been reported but the biological validity and the full-length nature of these variants have not been determined.

Genbezeichner und Symbole assoziert mit TP63

  • tumor protein p63 (TP63) Antikörper
  • tumor protein p63 (tp63) Antikörper
  • tumor protein p63 (LOC100227936) Antikörper
  • tumor protein p73-like (LOC100393670) Antikörper
  • tumor protein p73-like (LOC100433100) Antikörper
  • tumor protein p73-like (LOC100480840) Antikörper
  • tumor protein p73-like (LOC100496308) Antikörper
  • tumor protein p73-like (LOC100512967) Antikörper
  • tumor protein p73-like (LOC100545037) Antikörper
  • tumor protein p73-like (LOC100577122) Antikörper
  • tumor protein p73-like (LOC100594205) Antikörper
  • tumor protein p73-like (LOC100611345) Antikörper
  • tumor protein p73-like (LOC100624851) Antikörper
  • tumor protein p73-like (LOC100648488) Antikörper
  • t-complex protein 1 (Tcp1) Antikörper
  • transformation related protein 63 (Trp63) Antikörper
  • tumor protein p63 (Tp63) Antikörper
  • tumor protein p63-like (LOC100355881) Antikörper
  • AI462811 Antikörper
  • AI528772 Antikörper
  • AIS Antikörper
  • B(p51A) Antikörper
  • B(p51B) Antikörper
  • c-cpn Antikörper
  • CCT Antikörper
  • Cct1 Antikörper
  • Ccta Antikörper
  • DNp63 Antikörper
  • EEC3 Antikörper
  • id:ibd3516 Antikörper
  • ket Antikörper
  • LMS Antikörper
  • NBP Antikörper
  • np63 Antikörper
  • OFC8 Antikörper
  • p40 Antikörper
  • p51 Antikörper
  • P51/P63 Antikörper
  • p53CP Antikörper
  • P63 Antikörper
  • p73H Antikörper
  • p73L Antikörper
  • RHS Antikörper
  • SHFM4 Antikörper
  • Tcp-1 Antikörper
  • TP53CP Antikörper
  • TP53L Antikörper
  • Tp63 Antikörper
  • tp73l Antikörper
  • tp73l-A Antikörper
  • TRic Antikörper
  • Trp53rp1 Antikörper
  • TRP63 Antikörper
  • wu:fc89f04 Antikörper
  • wu:fk85h07 Antikörper
  • wu:fk88b02 Antikörper
  • Xp63 Antikörper

Bezeichner auf Proteinebene für TP63

tumor protein p63 , tumor protein 63 , p63 gamma , tumor protein p73-like , tumor protein 63-like , CCT-alpha , T-complex protein 1 subunit alpha , T-complex protein 1 subunit alpha A , T-complex protein 1 subunit alpha B , TCP-1-A , TCP-1-B , TCP-1-alpha , t-complex polypeptide 1 , tailless complex polypeptide 1A , tailless complex polypeptide 1B , transformation-related protein 63 , CUSP , amplified in squamous cell carcinoma , chronic ulcerative stomatitis protein , keratinocyte transcription factor KET , tumor protein p53-competing protein , tumor protein p63 deltaN isoform delta , transformation related protein 63 , tumor protein 63 kDa , delta-Np63 , fc89f04

100059752 Equus caballus
100170632 Oryzias latipes
703997 Macaca mulatta
100048992 Ovis aries
460930 Pan troglodytes
100227936 Taeniopygia guttata
100386953 Callithrix jacchus
100393670 Callithrix jacchus
100433100 Pongo abelii
100444448 Pongo abelii
100480840 Ailuropoda melanoleuca
100496308 Xenopus (Silurana) tropicalis
100512967 Sus scrofa
100545037 Meleagris gallopavo
100577122 Apis mellifera
100594205 Nomascus leucogenys
100606847 Nomascus leucogenys
100611345 Pan troglodytes
100624851 Sus scrofa
100648488 Bombus terrestris
21454 Mus musculus
22061 Mus musculus
8626 Homo sapiens
246334 Rattus norvegicus
260407 Danio rerio
373640 Xenopus laevis
374269 Gallus gallus
100732143 Cavia porcellus
100625258 Sus scrofa
488125 Canis lupus familiaris
615335 Bos taurus
101108874 Ovis aries
100355881 Oryctolagus cuniculus
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