anti-Tumor Protein P63 (TP63) Antikörper

TP63 encodes a member of the p53 family of transcription factors. Zusätzlich bieten wir Ihnen p63 Kits (28) und p63 Proteine (7) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
TP63 21454 P11983
TP63 8626 Q9H3D4
TP63 246334 Q9JJP6
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Top anti-p63 Antikörper auf antikoerper-online.de

Showing 10 out of 79 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert WB TP63 Antibody (C-term) (ABIN657886) western blot analysis in MDA-MB231 cell line lysates (35 µg/lane). This demonstrates the TP63 antibody detected the TP63 protein (arrow). 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Kaninchen Unkonjugiert ICC, IHC (p), WB Anti-p63 Picoband antibody,  IHC(P): Human Oesophagus Squama Cancer Tissue Anti-p63 Picoband antibody,  All lanes: Anti P63  at 0.5ug/ml WB: Recombinant Human P63 Protein 0.5ng Predicted bind size: 39KD Observed bind size: 39KD 100 μg Anmelden zum Anzeigen 8 bis 11 Tage
340,48 €
Details
Human Kaninchen Unkonjugiert ICC, IHC (p), WB Anti-p63 antibody, IHC(P) IHC(P): Human Lung Cancer Tissue Anti-p63 antibody, Western blotting Lane 1: HELA Cell Lysate Lane 2: SMMC Cell Lysate Lane 3: COLO320 Cell Lysate Lane 4: A549 Cell Lysate Lane 5: SGC Cell Lysate 100 μg Anmelden zum Anzeigen 8 bis 11 Tage
298,57 €
Details
Human Maus Unkonjugiert IHC, WB 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
366,67 €
Details
Human Ziege Unkonjugiert ELISA, WB 0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
505,48 €
Details
Human Maus Unkonjugiert IHC (p) Detection of p63 protein in nucleus of epidermis stained with anti-p63 antibody 10 mL Anmelden zum Anzeigen 1 bis 2 Tage
330,00 €
Details
Human Maus Unkonjugiert WB TP63 Antibody (Ascites) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the TP63 antibody detected the TP63 protein (arrow). 0.1 mL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Kaninchen Unkonjugiert IHC, WB Immunohistochemistry of paraffin-embedded rat kidney using TP63 antibody at dilution of 1:100 (x400 lens). 100 μL Anmelden zum Anzeigen 12 Days
261,90 €
Details
Human Maus Unkonjugiert ELISA, WB Detection limit for recombinant GST tagged TP73L is approximately 0.3 ng/mL as a capture antibody. 0.1 mg Anmelden zum Anzeigen 12 bis 16 Tage
454,76 €
Details
Human Maus Unkonjugiert IHC (p)   5 mL Anmelden zum Anzeigen 1 bis 2 Tage
165,00 €
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TP63 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-p63 Antikörper

  1. Human Polyclonal p63 Primary Antibody für WB - ABIN657886 : Miki, Kubo, Takahashi, Yoon, Kim, Lee, Zo, Lee, Hosono, Morizono, Tsunoda, Kamatani, Chayama, Takahashi, Inazawa, Nakamura, Daigo: Variation in TP63 is associated with lung adenocarcinoma susceptibility in Japanese and Korean populations. in Nature genetics 2010 (PubMed)
    Show all 2 Pubmed References

  2. Human Monoclonal p63 Primary Antibody für IHC, WB - ABIN2673817 : Zhang, Wei, Dang, Xie, Zhong, Ma, Chen: Primary urinary bladder adenosquamous carcinoma complicated with lower limb deep venous thromboses: a case report. in International journal of clinical and experimental pathology 2015 (PubMed)

Weitere Antikörper gegen p63 Interaktionspartner

Horse (Equine) Tumor Protein P63 (TP63) Interaktionspartner

  1. p63 expression was significantly lower in the chronic laminitic hoof than in that of control horses

Mouse (Murine) Tumor Protein P63 (TP63) Interaktionspartner

  1. Data suggest that this the selective targeting of genes by tumor suppressor protein (zeige TP53 Antikörper) p63 (p63 (zeige CKAP4 Antikörper)) correlates with subtle, but measurable transcriptional differences in mouse and human keratinocytes that converges on major metabolic processes, which often exhibit species-specific trends.

  2. p63alpha protein up-regulates heat shock protein 70 (zeige HSP70 Antikörper) expression via E2F1 transcription factor (zeige E2F1 Antikörper) 1 (zeige HNF1A Antikörper), promoting Wasf3/Wave3 (zeige WASF3 Antikörper)/MMP9 (zeige MMP9 Antikörper) signaling and bladder cancer invasion

  3. these results therefore highlight an unanticipated role for p53 (zeige TP53 Antikörper) family proteins in a regulatory network that integrates essential Wnt (zeige WNT2 Antikörper)-Tcf (zeige HNF4A Antikörper) and nodal-Smad (zeige SMAD1 Antikörper) inputs.

  4. the double mutant spermatocytes apoptosed at late pachynema because of sex body deficiency; thus p53 (zeige TP53 Antikörper) and TAp63 are dispensable for arrest caused by sex body defects. These data affirm that recombination-dependent and sex body-deficient arrests occur via genetically separable mechanisms.

  5. TGFb3 (zeige TGFB3 Antikörper)-induced down-regulation of p63 (zeige CKAP4 Antikörper) in the medial edge epithelia of the palatal shelves is a pre-requisite for palatal fusion by facilitating periderm migration from, and reducing the proliferative potential of, the midline epithelial seam thereby preventing cleft palate.

  6. miR (zeige MLXIP Antikörper)-20a-5p contributes to hepatic glycogen (zeige GYS1 Antikörper) synthesis through targeting p63 (zeige CKAP4 Antikörper) to regulate p53 (zeige TP53 Antikörper) and PTEN (zeige PTEN Antikörper) expression.

  7. this study shows that CCTalpha (zeige PCYT1A Antikörper) is required for antigen-specific, germinal center-derived memory B cells

  8. Taken together, these data show that p63 (zeige CKAP4 Antikörper) regulates the self-renewal and differentiation of oesophageal stem cells in humans and mice.

  9. IL-6 (zeige IL6 Antikörper)/P-STAT3 (zeige STAT3 Antikörper) activation influences p63 (zeige CKAP4 Antikörper) isoform expression in healing wounds, which may contribute to wound-induced hair follicle neogenesis.

  10. In vivo inhibition of both p63 (zeige CKAP4 Antikörper) and p73 (zeige ARHGAP24 Antikörper) in combination accelerates tumor regression and increases survival of p53 (zeige TP53 Antikörper)-deficient mice.

Human Tumor Protein P63 (TP63) Interaktionspartner

  1. Allele-specific silencing of ectrodactily-ectodermal dysplasia and cleft lip/palate syndrome p63 (zeige RPE65 Antikörper) mutant R304W restores p63 (zeige RPE65 Antikörper) transcriptional activity.

  2. Data suggest that this the selective targeting of genes by tumor suppressor protein (zeige TP53 Antikörper) p63 (p63 (zeige RPE65 Antikörper)) correlates with subtle, but measurable transcriptional differences in mouse and human keratinocytes that converges on major metabolic processes, which often exhibit species-specific trends.

  3. This report illustrates the potential severity of urogenital defects in TP63-related disorders, which may be detectable with fetal ultrasonography. It highlights the need to counsel for the possibility of germline mosaicism in TP63-associated disorders.

  4. p63alpha protein up-regulates heat shock protein 70 (zeige HSP70 Antikörper) expression via E2F1 transcription factor (zeige E2F1 Antikörper) 1 (zeige HNF1A Antikörper), promoting Wasf3/Wave3 (zeige WASF3 Antikörper)/MMP9 (zeige MMP9 Antikörper) signaling and bladder cancer invasion

  5. High TP63 expression is associated with growth, metastasis and stemness of oral squamous cell carcinoma.

  6. present observations strongly suggest that RUNX2 (zeige RUNX2 Antikörper)/mutant p53 (zeige TP53 Antikörper)/TAp63-regulatory axis is one of the key determinants of SAHA sensitivity of p53 (zeige TP53 Antikörper)-mutated pancreatic cancer cells

  7. a major effect of p63 (zeige RPE65 Antikörper) is regulation of cell adhesion, a process important in metastasis and invasion of tumour cells. That this effect is not seen in mesenchymal-type TNBC cells suggests lineage-dependent functions, mirroring the expression of Np63alpha in primary human breast cancers.

  8. p63 (zeige RPE65 Antikörper) is a master regulator in epidermal biology and regulates glycolysis sugar taste in the epidermis.

  9. Anaplastic large cell lymphomas without TP63 rearrangements may express TAp63 isoforms of p63 (zeige RPE65 Antikörper) and this expression is associated with extra copies of TP63, probably due to widespread genomic copy number abnormalities rather than focal gains.

  10. Up-regulation of transcription factor DeltaNp63 led to the decline of miR (zeige MLXIP Antikörper)-181a expression, resulting in an overexpression of the antiaging protein Sirt1 (zeige SIRT1 Antikörper), in CD4 (zeige CD4 Antikörper)(+) T cells from HCV-infected individuals. Either reconstituting miR (zeige MLXIP Antikörper)-181a or silencing DeltaNp63 or Sirt1 (zeige SIRT1 Antikörper) expression in CD4 (zeige CD4 Antikörper)(+) T cells led to accelerated T cell senescence.

Zebrafish Tumor Protein P63 (TP63) Interaktionspartner

  1. they unravel essential roles of TAp63 and p53 (zeige TP53 Antikörper) to promote both keratinocyte proliferation and their terminal differentiation by promoting Notch (zeige NOTCH1 Antikörper) signalling and caspase 3 (zeige CASP3 Antikörper) activity.

  2. the p63 transcription factor is upregulated to initiate this apoptotic pathway and directly activates puma (zeige BBC3 Antikörper) transcription in response to ER stress.

  3. Early zebrafish embryos express a dominant-negative form of p63 (DeltaNp63), which accumulates in the nucleus just as epidermal growth begins. (p63)

  4. DeltaNp63 expression blocks neural development and promotes nonneural development, even in the absence of Bmp signaling. (DeltaNp63)

  5. rps19 (zeige RPS19 Antikörper)-deficient phenotype is mediated by dysregulation of deltaNp63 and p53 (zeige TP53 Antikörper) and results in hematopoietic and developmental abnormalities resembling Diamond-Blackfan anemia

Xenopus laevis Tumor Protein P63 (TP63) Interaktionspartner

  1. Data indicate that pluripotency genes sox2, p63 and oct60 are upregulated early during the process of lens regeneration.

  2. The results suggest that DeltaNp63 is an essential gene in early epidermal specification under the control of BMP4 (zeige BMP4 Antikörper).

  3. The role of p63 as a negative Wnt (zeige WNT2 Antikörper)-regulator thus matches with the frequently observed downregulation of p63 during tumor progression, when cancer cells adopt a more mesenchymal, invasive phenotype.

p63 (TP63) Antigen-Profil

Protein Überblick

This gene encodes a member of the p53 family of transcription factors. An animal model, p63 -/- mice, has been useful in defining the role this protein plays in the development and maintenance of stratified epithelial tissues. p63 -/- mice have several developmental defects which include the lack of limbs and other tissues, such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3)\; split-hand/foot malformation 4 (SHFM4)\; ankyloblepharon-ectodermal defects-cleft lip/palate\; ADULT syndrome (acro-dermato-ungual-lacrimal-tooth)\; limb-mammary syndrome\; Rap-Hodgkin syndrome (RHS)\; and orofacial cleft 8. Both alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different proteins. Many transcripts encoding different proteins have been reported but the biological validity and the full-length nature of these variants have not been determined.

Genbezeichner und Symbole assoziert mit TP63

  • tumor protein p63 (TP63) Antikörper
  • tumor protein p63 (tp63) Antikörper
  • tumor protein p63 (LOC100227936) Antikörper
  • tumor protein p73-like (LOC100393670) Antikörper
  • tumor protein p73-like (LOC100433100) Antikörper
  • tumor protein p73-like (LOC100480840) Antikörper
  • tumor protein p73-like (LOC100496308) Antikörper
  • tumor protein p73-like (LOC100512967) Antikörper
  • tumor protein p73-like (LOC100545037) Antikörper
  • tumor protein p73-like (LOC100577122) Antikörper
  • tumor protein p73-like (LOC100594205) Antikörper
  • tumor protein p73-like (LOC100611345) Antikörper
  • tumor protein p73-like (LOC100624851) Antikörper
  • tumor protein p73-like (LOC100648488) Antikörper
  • t-complex protein 1 (Tcp1) Antikörper
  • transformation related protein 63 (Trp63) Antikörper
  • tumor protein p63 (Tp63) Antikörper
  • tumor protein p63-like (LOC100355881) Antikörper
  • AI462811 Antikörper
  • AI528772 Antikörper
  • AIS Antikörper
  • B(p51A) Antikörper
  • B(p51B) Antikörper
  • c-cpn Antikörper
  • CCT Antikörper
  • Cct1 Antikörper
  • Ccta Antikörper
  • DNp63 Antikörper
  • EEC3 Antikörper
  • id:ibd3516 Antikörper
  • ket Antikörper
  • LMS Antikörper
  • NBP Antikörper
  • np63 Antikörper
  • OFC8 Antikörper
  • p40 Antikörper
  • p51 Antikörper
  • P51/P63 Antikörper
  • p53CP Antikörper
  • P63 Antikörper
  • p73H Antikörper
  • p73L Antikörper
  • RHS Antikörper
  • SHFM4 Antikörper
  • Tcp-1 Antikörper
  • TP53CP Antikörper
  • TP53L Antikörper
  • Tp63 Antikörper
  • tp73l Antikörper
  • tp73l-A Antikörper
  • TRic Antikörper
  • Trp53rp1 Antikörper
  • TRP63 Antikörper
  • wu:fc89f04 Antikörper
  • wu:fk85h07 Antikörper
  • wu:fk88b02 Antikörper
  • Xp63 Antikörper

Bezeichner auf Proteinebene für TP63

tumor protein p63 , tumor protein 63 , p63 gamma , tumor protein p73-like , tumor protein 63-like , CCT-alpha , T-complex protein 1 subunit alpha , T-complex protein 1 subunit alpha A , T-complex protein 1 subunit alpha B , TCP-1-A , TCP-1-B , TCP-1-alpha , t-complex polypeptide 1 , tailless complex polypeptide 1A , tailless complex polypeptide 1B , transformation-related protein 63 , CUSP , amplified in squamous cell carcinoma , chronic ulcerative stomatitis protein , keratinocyte transcription factor KET , tumor protein p53-competing protein , tumor protein p63 deltaN isoform delta , transformation related protein 63 , tumor protein 63 kDa , delta-Np63 , fc89f04

GENE ID SPEZIES
100059752 Equus caballus
100170632 Oryzias latipes
703997 Macaca mulatta
100048992 Ovis aries
460930 Pan troglodytes
100227936 Taeniopygia guttata
100386953 Callithrix jacchus
100393670 Callithrix jacchus
100433100 Pongo abelii
100444448 Pongo abelii
100480840 Ailuropoda melanoleuca
100496308 Xenopus (Silurana) tropicalis
100512967 Sus scrofa
100545037 Meleagris gallopavo
100577122 Apis mellifera
100594205 Nomascus leucogenys
100606847 Nomascus leucogenys
100611345 Pan troglodytes
100624851 Sus scrofa
100648488 Bombus terrestris
21454 Mus musculus
22061 Mus musculus
8626 Homo sapiens
246334 Rattus norvegicus
260407 Danio rerio
373640 Xenopus laevis
374269 Gallus gallus
100732143 Cavia porcellus
100625258 Sus scrofa
488125 Canis lupus familiaris
615335 Bos taurus
101108874 Ovis aries
100355881 Oryctolagus cuniculus
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