anti-Tumor Protein P53 Binding Protein 2 (TP53BP2) Antikörper

TP53BP2 encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. Zusätzlich bieten wir Ihnen Tumor Protein P53 Binding Protein 2 Proteine (3) und Tumor Protein P53 Binding Protein 2 Kits (2) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
TP53BP2 21981 Q62415
TP53BP2 7159 Q13625
TP53BP2 305025  
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Showing 10 out of 71 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Human Kaninchen Unkonjugiert EIA, WB TP53BP2 Antibody (N-term) western blot analysis in T47D cell line lysates (35 µg/lane). This demonstrates the TP53BP2 antibody detected the TP53BP2 protein (arrow). 0.4 mL Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin embedded mouse lung labeled with Rabbit Anti-ASPP2/p53BP2 Polyclonal Antibody, Unconjugated (ABIN674394) at 1:200 followed by conjugation to the secondary antibody and DAB staining Lane 1: Mouse spleen lysate Lane 2: Mouse thymus lysate Lane 3: Mouse prostate lysate Lane 4: Mouse intestine lysate probed with Rabbit Anti-ASPP2/p53BP2 Polyclonal Antibody, Unconjugated (ABIN674394) at 1:300 overnight at 4 °C. Followed by conjugation to secondary antibody  at 1:5000 for 90 min at 37 °C. 100 μL Anmelden zum Anzeigen 9 bis 12 Tage
304,36 €
Details
Human Maus Unkonjugiert IF, WB Western blot analysis of 53BP2 on human endothelial lysate. Lane 1: 1:250, lane 2: 1:500, lane 3: 1:1000 dilution of 53BP2. Endothelial Cells 50 μg Anmelden zum Anzeigen 2 bis 4 Tage
146,73 €
Details
Human Kaninchen Unkonjugiert IHC, ELISA, WB ASPP2 staining in human uterine cancer tissue. Paraffin-embedded human uterine cancer tissue is stained with ASPP2 Antibody used at 1:200 dilution. 0.1 mg Anmelden zum Anzeigen 6 bis 11 Tage
368,76 €
Details
Hund Kaninchen Unkonjugiert EIA, WB   0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
391,60 €
Details
Human Kaninchen Unkonjugiert WB TP53BP2 Antibody (N-term)  western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the TP53BP2 antibody detected the TP53BP2 protein (arrow). 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Kaninchen Unkonjugiert WB Western Blot: 53BP2 Antibody [NBP2-21589] - Sample (30 ug of whole cell lysate) A: NT2D1 7. 5% SDS PAGE gel, diluted at 1:1000. 0.1 mL Anmelden zum Anzeigen 3 bis 6 Tage
341,00 €
Details
Human Kaninchen Unkonjugiert WB WB Image Sample (30 ug of whole cell lysate) A: NT2D1 7.5% SDS PAGE antibody diluted at 1:1000 100 μL Anmelden zum Anzeigen 5 bis 7 Tage
357,24 €
Details
Human Kaninchen Unkonjugiert ELISA, WB Western blot using Protein A purified anti-ASPP2 to detect over-expressed ASPP2 in MCF-7 cells (Lane 2, arrowhead). Lane 1 is a nontransfected control. Lane 3 is MCF-7 cells over-expressing ASPP1. Cell extracts were electrophoresed and transferred to nitrocellulose. The membrane was probed with the primary antibody at a 1:1,000 dilution. The identity of the lower MW band at approximately 40kDa is unknown. 100 μg Anmelden zum Anzeigen 5 bis 7 Tage
412,76 €
Details

TP53BP2 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-Tumor Protein P53 Binding Protein 2 Antikörper

  1. Human Monoclonal TP53BP2 Primary Antibody für IF, WB - ABIN968491 : Iwabuchi, Li, Massa, Trask, Date, Fields: Stimulation of p53-mediated transcriptional activation by the p53-binding proteins, 53BP1 and 53BP2. in The Journal of biological chemistry 1998 (PubMed)
    Zeige alle 3 Referenzen für 968491

  2. Human Polyclonal TP53BP2 Primary Antibody für EIA, WB - ABIN955298 : Hirata, Hinoda, Nakajima, Kikuno, Suehiro, Tabatabai, Ishii, Dahiya: The bcl2 -938CC genotype has poor prognosis and lower survival in renal cancer. in The Journal of urology 2009 (PubMed)
    Zeige alle 3 Referenzen für 955298

  3. Cow (Bovine) Polyclonal TP53BP2 Primary Antibody für WB - ABIN2780683 : Ju, Lee, Yang, Kim, Kang, Sohn, Rhee, Kang, Kim: TP53BP2 locus is associated with gastric cancer susceptibility. in International journal of cancer. Journal international du cancer 2005 (PubMed)

  4. Human Polyclonal TP53BP2 Primary Antibody für IHC, ELISA - ABIN1584022 : Matsumoto, Weckbecker, Cory: Antineoplastic effect of the combination of 2,3-dihydro-1H-pyrazole[2,3a]imidazole plus deoxyadenosine/erythro-9-(2-hydroxyl-3-nonyl)adenine in mice with L1210 leukemia cells. in Cancer communications 1990 (PubMed)

  5. Human Polyclonal TP53BP2 Primary Antibody für IF (p), IHC (p) - ABIN674394 : Xie, Yang, Chi, Yang, Wang, Xu: Prognostic values of apoptosis-stimulating P53-binding protein 1 and 2 and their relationships with clinical characteristics of esophageal squamous cell carcinoma patients: a retrospective study. in Chinese journal of cancer 2017 (PubMed)

Weitere Antikörper gegen Tumor Protein P53 Binding Protein 2 Interaktionspartner

Zebrafish Tumor Protein P53 Binding Protein 2 (TP53BP2) Interaktionspartner

  1. These findings uncover a novel role of Aspp2 in regulating vertebrate embryonic growth.

Mouse (Murine) Tumor Protein P53 Binding Protein 2 (TP53BP2) Interaktionspartner

  1. SPP2 dominates the biological outcome, thus switching from a Gal-1 supported growth-promoting setting to a senescence inducing and stemness suppressive program in cancer cells. Our results support Ras nanocluster as major integrators of tumour fate decision events.

  2. After genotoxic stress, Aspp1 (zeige PPP1R13B Antikörper) promotes hematopoietic stem cell (HSC (zeige FUT1 Antikörper)) cycling and induces p53 (zeige TP53 Antikörper)-dependent apoptosis in cells with persistent DNA damage foci. Aspp1 (zeige PPP1R13B Antikörper) also attenuates HSC (zeige FUT1 Antikörper) self-renewal and accumulation of DNA damage in p53 (zeige TP53 Antikörper) null HSCs.

  3. ASPP2 may participate in the lipid metabolism of non-alcoholic steatohepatitis and attenuate liver failure.

  4. ASPP2 prevents beta-catenin (zeige CTNNB1 Antikörper) from transactivating ZEB1 (zeige ZEB1 Antikörper) directly by forming an ASPP2-beta-catenin (zeige CTNNB1 Antikörper)-E-cadherin (zeige CDH1 Antikörper) ternary complex

  5. findings suggest that the identified STAT1 (zeige STAT1 Antikörper)/ASPP2 pathway may connect tumor suppression and cell polarity to neuroinflammation

  6. our studies demonstrate the role of Siah2 (zeige SIAH2 Antikörper) in regulation of tight junction integrity and cell polarity under hypoxia, through its regulation of ASPP2 stability.

  7. ASPP2 is a tumor suppressor that suppresses squamous cell carcinoma via inflammatory signaling through NF-kappaB (zeige NFKB1 Antikörper)-mediated repression of p63 (zeige CKAP4 Antikörper).

  8. Our study demonstrates a novel role for ASPP1 (zeige PPP1R13B Antikörper) and ASPP2 in the death of retinal ganglion cells.

  9. regulates epithelial cell polarity in cooperation with PAR-3 (zeige F2RL2 Antikörper) to form an active PAR (zeige AFG3L2 Antikörper) complex

  10. Consistent with its role in cell polarity, ASPP2 influences interkinetic nuclear migration and lamination during CNS development.

Human Tumor Protein P53 Binding Protein 2 (TP53BP2) Interaktionspartner

  1. Expression levels of TP53BP2, FBXO28 (zeige FBXO28 Antikörper), and FAM53A (zeige Fam53a Antikörper) genes were associated with patient survival specifically in ER-positive, TP53 (zeige TP53 Antikörper)-mutated tumors.

  2. These data together implicated a critical impact of MiR (zeige MLXIP Antikörper)-205/ASPP2 on promoting epithelial-mesenchymal transition.

  3. ASPP2 is a key regulator of BECN1 (zeige BECN1 Antikörper)-dependent autophagy.

  4. ASPP2 suppresses invasion, peritoneal dissemination and TGF-beta1 (zeige TGFB1 Antikörper)-induced EMT (zeige ITK Antikörper) by inhibiting Smad7 (zeige SMAD7 Antikörper) degradation mediated by ITCH in gastric cancer cells.

  5. Our results suggest that Gal-1 and ASPP2 functionally compete in nanocluster for active Ras on the plasma membrane. ASPP2 dominates the biological outcome, thus switching from a Gal-1 supported growth-promoting setting to a senescence inducing and stemness suppressive program in cancer cells. Our results support Ras nanocluster as major integrators of tumour fate decision events.

  6. ASPP2 suppresses p53 (zeige TP53 Antikörper) target gene transactivation, promoter occupancy, and endogenous p53 (zeige TP53 Antikörper) target gene expression in response to DNA damage

  7. In this study, in recombinant adenovirus-ASPP2-infected HepG2 cells, ASPP2 overexpression induces amphiregulin (zeige AREG Antikörper) expression in a p53 (zeige TP53 Antikörper)-dependent manner

  8. Downregulated expression of ASPP2 is associated with hepatocellular carcinoma.

  9. miR (zeige MLXIP Antikörper)-548d-3p/TP53BP2 pathway is critically involved in the proliferation and apoptosis of breast cancer cells and may be new therapeutic target of breast cancer cells.

  10. ASPP1 (zeige PPP1R13B Antikörper)/2-PP1 (zeige PPA1 Antikörper) complexes are required for chromosome segregation and kinetochore-microtubule attachments.

Tumor Protein P53 Binding Protein 2 (TP53BP2) Antigen-Profil

Protein Überblick

This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. It is localized to the perinuclear region of the cytoplasm, and regulates apoptosis and cell growth through interactions with other regulatory molecules including members of the p53 family. Multiple transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit TP53BP2

  • tumor protein p53 binding protein, 2 (TP53BP2) Antikörper
  • tumor protein p53 binding protein, 2 (tp53bp2) Antikörper
  • si:dkeyp-34c12.2 (si:dkeyp-34c12.2) Antikörper
  • protein phosphatase 1, regulatory (inhibitor) subunit 13B (Ppp1r13b) Antikörper
  • transformation related protein 53 binding protein 2 (Trp53bp2) Antikörper
  • tumor protein p53 binding protein, 2 (Tp53bp2) Antikörper
  • 53BP2 Antikörper
  • AI449786 Antikörper
  • AI746547 Antikörper
  • ASPP1 Antikörper
  • ASPP2 Antikörper
  • AW545810 Antikörper
  • BBP Antikörper
  • P53BP2 Antikörper
  • p85 Antikörper
  • PPP1R13A Antikörper
  • Tp53bp2 Antikörper
  • Trp53bp2 Antikörper
  • wu:fa09h08 Antikörper
  • wu:fb04e08 Antikörper
  • X98550 Antikörper
  • zgc:85720 Antikörper

Bezeichner auf Proteinebene für TP53BP2

tumor protein p53 binding protein, 2 , apoptosis-stimulating of p53 protein 2-like , apoptosis-stimulating of p53 protein 1 , protein phosphatase 1 regulatory subunit 13B , transformation related protein 53 binding protein 2 , tumor protein p53-binding protein, 2 , apoptosis-stimulating of p53 protein 2 , p53-binding protein 2 , p53BP2 , tumor suppressor p53-binding protein 2 , fb04e08 , BCL2-binding protein , apoptosis-stimulating protein of p53, 2 , renal carcinoma antigen NY-REN-51

GENE ID SPEZIES
421329 Gallus gallus
457766 Pan troglodytes
548790 Xenopus (Silurana) tropicalis
568138 Danio rerio
705383 Macaca mulatta
100055278 Equus caballus
100221962 Taeniopygia guttata
100445132 Pongo abelii
100519863 Sus scrofa
21981 Mus musculus
209456 Mus musculus
407983 Danio rerio
446947 Xenopus laevis
7159 Homo sapiens
490397 Canis lupus familiaris
514474 Bos taurus
305025 Rattus norvegicus
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