anti-Tropomyosin 4 (TPM4) Antikörper

TPM4 encodes a member of the tropomyosin family of actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Zusätzlich bieten wir Ihnen Tropomyosin 4 Proteine (14) und Tropomyosin 4 Kits (6) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
TPM4 7171 P67936
TPM4 326618 Q6IRU2
TPM4 24852 P09495
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Showing 10 out of 46 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert EIA, WB TPM4 Antibody (N-term) western blot analysis in U251,A549,Jurkat cell line lysates (35 µg/lane). This demonstrates the TPM4 antibody detected the TPM4 protein (arrow). 0.4 mL Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
Details
Human Kaninchen Unkonjugiert FACS, WB TPM4 Antibody (N-term) (ABIN656684) western blot analysis in U251,A549,Jurkat cell line lysates (35 µg/lane). This demonstrates the TPM4 antibody detected the TPM4 protein (arrow). 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Maus Unkonjugiert IF, IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to TPM4 on formalin-fixed paraffin-embedded human transitional cell carcinoma tissue. [antibody concentration 2 ug/ml] Immunofluorescence of monoclonal antibody to TPM4 on HeLa cell. [antibody concentration 10 ug/ml] 100 μg Anmelden zum Anzeigen 7 bis 8 Tage
369,60 €
Details
Human Kaninchen Unkonjugiert IHC, ELISA 100 μL Anmelden zum Anzeigen 11 bis 14 Tage
460,95 €
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Human Maus Unkonjugiert IF, IHC (p), ELISA, WB 100 μg Anmelden zum Anzeigen 11 bis 14 Tage
635,55 €
Details
Rind (Kuh) Ziege Unkonjugiert ELISA, WB ABIN4902783 (0.03µg/ml) staining of Human Platelets lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. ABIN4902783 (0.1µg/ml) staining of NIH3T3 lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μL Anmelden zum Anzeigen 12 Days
363,76 €
Details
Maus Kaninchen Unkonjugiert WB Western blot analysis of extracts of mouse lung and rat heart cells, using TPM4 antibody. 100 μL Anmelden zum Anzeigen 12 Days
261,90 €
Details
Human Maus Unkonjugiert IF, WB Immunofluorescence of monoclonal antibody to TPM4 on HeLa cell (antibody concentration 10 µg/mL).  TPM4 monoclonal antibody (M01), clone 4E4-1D2 Western Blot analysis of TPM4 expression in Hela. 0.1 mg Anmelden zum Anzeigen 12 bis 16 Tage
454,76 €
Details
Rind (Kuh) Ziege Unkonjugiert ELISA, WB   100 μg Anmelden zum Anzeigen 11 bis 14 Tage
722,86 €
Details
Human Maus Unkonjugiert IF, IHC (p), WB 0.1 mg Anmelden zum Anzeigen 4 bis 5 Tage
601,76 €
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TPM4 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-Tropomyosin 4 Antikörper

  1. Human Monoclonal TPM4 Primary Antibody für IF, IHC (p) - ABIN563237 : Häbig, Gellhaar, Heim, Djuric, Giesert, Wurst, Walter, Hentrich, Riess, Bonin: LRRK2 guides the actin cytoskeleton at growth cones together with ARHGEF7 and Tropomyosin 4. in Biochimica et biophysica acta 2013 (PubMed)

Weitere Antikörper gegen Tropomyosin 4 Interaktionspartner

Human Tropomyosin 4 (TPM4) Interaktionspartner

  1. findings demonstrate a nonredundant role for TPM4 in platelet biogenesis in humans and mice and reveal that truncating variants in TPM4 cause a previously undescribed dominant Mendelian platelet disorder.

  2. In diabetes, expression of high molecular weight (HMW) isoforms from tropomyosin 1 (TPM1 (zeige TPM1 Antikörper)) were markedly decreased but HMW isoforms from tropomyosin 4 (TPM4) were not significantly different.

  3. Results show that Tpm4.2 facilitates the transition of NM-2A to the strongly actin-binding myosin-ADP state.

  4. In addition to CLIC1 (zeige CLIC1 Antikörper) and TPM1 (zeige TPM1 Antikörper), which were the proteins initially discovered in a xenograft mouse model, CLIC4 (zeige CLIC4 Antikörper), TPM2 (zeige TPM2 Antikörper), TPM3 (zeige TPM3 Antikörper), and TPM4 were present in ovarian cancer patient sera at significantly elevated levels compared with controls.

  5. Data indicate the upregulation of tropomyosin-4 in infiltrating ductal breast carcinomas (IDCAs) tissues, which may suggest its involvement in breast cancer development.

  6. Plasma peroxiredoxins 1 and 2, and tropomyosin 4 were shown to associate with asbestos-exposure, and peroxiredoxin 1 (zeige PRDX1 Antikörper) with lung cancer.

  7. TPM4, PDIA and SRC8 were also localized to the trophoblast cells, further highlighting the importance of these cytoskeletal remodelling proteins in early pregnancy

  8. Low TPM4 expression in the cytoplasm is associated with uterine cervix carcinogenesis.

  9. Tm4-defined cytoskeleton is a marker of growth and repair/regeneration in response to injury, disease state and stress in skeletal muscle.

Mouse (Murine) Tropomyosin 4 (TPM4) Interaktionspartner

  1. findings demonstrate a nonredundant role for TPM4 in platelet biogenesis in humans and mice and reveal that truncating variants in TPM4 cause a previously undescribed dominant Mendelian platelet disorder.

  2. Tm-4 is specifically enriched within and around osteoclast attachment structures, the sealing zone and podosomes.

  3. Tropomyosin 4 defines longitudinal filaments in mouse models of muscular dystrophy and nemaline myopathy.

  4. These results indicate that Tm-4 plays a role in regulating adhesion structures of osteoclasts, most likely by stabilizing the actin microfilaments present in podosomes and the sealing zone.

Pig (Porcine) Tropomyosin 4 (TPM4) Interaktionspartner

  1. upregulation of tropomyosin 4 (TM4) mRNA is a relevant marker of dedifferentiation in vascular smooth muscle cells.

Zebrafish Tropomyosin 4 (TPM4) Interaktionspartner

Tropomyosin 4 (TPM4) Antigen-Profil

Protein Überblick

This gene encodes a member of the tropomyosin family of actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosins are dimers of coiled-coil proteins that polymerize end-to-end along the major groove in most actin filaments. They provide stability to the filaments and regulate access of other actin-binding proteins. In muscle cells, they regulate muscle contraction by controlling the binding of myosin heads to the actin filament. Multiple transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit anti-Tropomyosin 4 (TPM4) Antikörper

  • tropomyosin 4 (TPM4) Antikörper
  • tropomyosin 4 (LOC100192321) Antikörper
  • tropomyosin 4 (Tpm4) Antikörper
  • tropomyosin 4a (tpm4a) Antikörper
  • 2610528G24Rik Antikörper
  • tpm4 Antikörper
  • wu:fb06e07 Antikörper
  • zgc:63909 Antikörper
  • zgc:103436 Antikörper

Bezeichner auf Proteinebene für anti-Tropomyosin 4 (TPM4) Antikörper

tropomyosin 4 , tropomyosin alpha-4 chain , TM30p1 , tropomyosin-4 , TM-4 , tropomycin 4

GENE ID SPEZIES
465115 Pan troglodytes
535277 Bos taurus
609879 Canis lupus familiaris
100192321 Taeniopygia guttata
7171 Homo sapiens
326618 Mus musculus
24852 Rattus norvegicus
397608 Sus scrofa
406437 Danio rerio
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