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This locus may represent a breast cancer candidate gene. Zusätzlich bieten wir Ihnen TACC1 Proteine (3) und TACC1 Kits (2) und viele weitere Produktgruppen zu diesem Protein an.
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The correlation between TACC1 expression and HER-2 (zeige ERBB2 Antikörper)-positive status indicates synergistic regulation of these two prognostic markers in gastric carcinoma patients.
TFF3 (zeige TFF3 Antikörper) and TACC1 over-expression in epithelial cells of surgically resected gastric cancer tissues was an independent predictor of short survival in gastric cancer patients.
These findings provide proof and the foundation for the molecular and biological relationships of ErbB-2 (zeige ERBB2 Antikörper) and TACC1 in breast cancer.
study reports that a small subset of glioblastoma multiforme tumors harbors oncogenic chromosomal translocations that fuse in-frame the tyrosine kinase (zeige TXK Antikörper) coding domains of fibroblast growth factor receptor genes(FGFR1 (zeige FGFR1 Antikörper) or FGFR3 (zeige FGFR3 Antikörper)) to the transforming acidic coiled-coil coding domains of TACC1 or TACC3 (zeige TACC3 Antikörper); the FGFR (zeige FGFR2 Antikörper)-TACC fusion protein displays oncogenic activity
the study demonstrated that TACC1 localizes at the midbody during cytokinesis and interacts with and is a substrate of Aurora-C (zeige AURKC Antikörper), which warrant further investigation in order to elucidate the functional significance of this interaction.
TACC1 depletion in the cell led to decreased RARalpha (zeige RARA Antikörper) and TRalpha (zeige THRA Antikörper) ligand-dependent transcriptional activity and to delocalization of TR from the nucleus to the cytoplasm.
Interaction of the transforming acidic coiled-coil 1 (TACC1) protein with ch-TOG and GAS41/NuBI1 suggests multiple TACC1-containing protein complexes in human cells
Down regulation of tacc1 controls mrna homeostasis in polarized cells and participates in oncogenic processes in human cancers
TACC1 and the mitotic kinase Aurora B (zeige AURKB Antikörper) belong to the same complex during cytokinesis.
TACC1 and a three-gene expression signature (TACC1, NOV (zeige NOV Antikörper), and PTTG1 (zeige PTTG1 Antikörper)) were identified as independent prognostic markers.
we show that T cells deficient for acetyl-CoA carboxylase 1 (zeige ACACA Antikörper) (TACC1) are dramatically less pathogenic than wild-type (WT) T cells in a lethal C57BL/6 into BALB/c model of acute GVHD and permitted sustained survival of recipient mice.
This locus may represent a breast cancer candidate gene. It is located close to FGFR1 on a region of chromosome 8 that is amplified in some breast cancers. Three transcript variants encoding different isoforms have been found for this gene.
transforming, acidic coiled-coil containing protein 1
, transforming acidic coiled-coil-containing protein 1-like
, gastric cancer antigen Ga55
, transforming acidic coiled-coil-containing protein 1
, transforming, acidic coiled-coil containing protein 1a