You are viewing an incomplete version of our website. Please click to reload the website as full version.

Tousled-Like Kinase 1 Proteine (TLK1)

The protein encoded by TLK1 is a serine/threonine kinase that may be involved in the regulation of chromatin assembly. Zusätzlich bieten wir Ihnen Tousled-Like Kinase 1 Antikörper (116) und Tousled-Like Kinase 1 Kits (1) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
TLK1 9874 Q9UKI8
TLK1 228012 Q8C0V0
Ratte TLK1 TLK1 311118  
Direkt bei antikoerper-online bestellen
  • +49 (0)241 95 163 153
  • +49 (0)241 95 163 155
  • Online bestellen
  • orders@antikoerper-online.de

Top Tousled-Like Kinase 1 Proteine auf antikoerper-online.de

Showing 7 out of 7 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
HOST_Baculovirus infected Insect Cells Human GST tag,His tag 50 μg Anmelden zum Anzeigen 18 bis 20 Tage
400,00 €
Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 66 Days
10.536,00 €
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 66 Days
10.536,00 €
Details
HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 6 bis 8 Tage
748,00 €
Details
HOST_Baculovirus infected Insect Cells Human GST tag   5 μg Anmelden zum Anzeigen 6 bis 8 Tage
306,74 €
Details
Insektenzellen Human GST tag   10 μg Anmelden zum Anzeigen 7 bis 9 Tage
304,76 €
Details

TLK1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , ,
, , ,
Mouse (Murine)

Am meisten referenzierte Tousled-Like Kinase 1 Proteine

  1. Human TLK1 Protein expressed in Baculovirus infected Insect Cells - ABIN2005117 : Silljé, Nigg: Identification of human Asf1 chromatin assembly factors as substrates of Tousled-like kinases. in Current biology : CB 2001 (PubMed)
    Zeige alle 3 Referenzen für ABIN2005117

Weitere Proteine zu Tousled-Like Kinase 1 (TLK1) Interaktionspartnern

Caenorhabditis elegans (C. elegans) Tousled-Like Kinase 1 (TLK1) Interaktionspartner

  1. TLK-1 contributes to chromosome condensation and segregation;TLK-1 functions in cytokinesis by localizing AIR-2 to the midzone microtubules.

  2. Tousled-like kinase (TLK-1) contributes to chromosome segregation as a substrate and regulator of the Aurora B kinase AIR-2.

Human Tousled-Like Kinase 1 (TLK1) Interaktionspartner

  1. Our results suggest that GA-mediated transient modulation of TLK1 activity promotes DNA repair and suppresses radiation cytoxicity in salivary gland cells.

  2. TLK1B mediated phosphorylation of Rad9 (zeige RAD9A Proteine) regulates its nuclear/cytoplasmic localization and cell cycle checkpoint

  3. Data indicate Tousled-like kinases (TLK1) phosphorylation has an impact on cell cycle proteins Asf1a (zeige ASF1A Proteine) and Asf1b (zeige ASF1B Proteine) function.

  4. Tousled-like kinase-dependent phosphorylation of Rad9 (zeige RAD9A Proteine) plays a role in cell cycle progression and G2/M checkpoint exit.

  5. Adenoviral delivery of Tousled kinase protects salivary glands against ionizing radiation damage.

  6. Silencing of TLK1 enhanced DNA damage induced by cisplatin treatment, suggesting that TLK1 plays a pivotal role for the repair of cisplatin-induced DNA damage.

  7. ASF1 (zeige SRSF1 Proteine) cellular levels are tightly controlled by distinct pathways and provide a molecular mechanism for post-translational regulation of dASF1 (zeige SRSF1 Proteine) and hASF1a (zeige ASF1A Proteine) by TLK (zeige TLK2 Proteine) kinases.

  8. we show that Chk1 (zeige CHEK1 Proteine) is essential for the suppression of TLK (zeige TLK2 Proteine) activity after replication block, but that ATR (zeige ANTXR1 Proteine), Chk2 (zeige CHEK2 Proteine) and BRCA1 are dispensable for TLK (zeige TLK2 Proteine) suppression.

  9. Both eIF4E (zeige EIF4E Proteine) and TLK1B are elevated in breast cancer specimens but not in benign breast specimens from noncancer patients. Degree of TLK1B elevation is correlated with degree of IF4E (zeige EIF4E2 Proteine) overexpression.

  10. In addition, it could be demonstrated that increasing the Tlk1 activity in HT1080 (zeige CDC123 Proteine) cells by forced Tlk1 overexpression leads to an increased phosphorylation of endogenous p68 (zeige ANXA6 Proteine).

Mouse (Murine) Tousled-Like Kinase 1 (TLK1) Interaktionspartner

Tousled-Like Kinase 1 (TLK1) Protein Überblick

Protein Überblick

The protein encoded by this gene is a serine/threonine kinase that may be involved in the regulation of chromatin assembly. The encoded protein is only active when it is phosphorylated, and this phosphorylation is cell cycle-dependent, with the maximal activity of this protein coming during S phase. The catalytic activity of this protein is diminished by DNA damage and by blockage of DNA replication. Three transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit Tousled-Like Kinase 1 Proteine (TLK1)

  • tousled-like kinase 1 (TLK1)
  • tousled-like kinase 1b (tlk1b)
  • tousled-like kinase 1 (LOC542181)
  • tousled-like kinase 1 (tlk1)
  • Protein TLK-1 (tlk-1)
  • tousled-like kinase 1 (Tlk1)
  • tousled-like kinase 1a (tlk1a)
  • 4930545J15Rik Protein
  • DKFZp459L163 Protein
  • fb76h12 Protein
  • fe11e12 Protein
  • PKU-beta Protein
  • si:dkey-88m1.1 Protein
  • si:dkey-251e16.4 Protein
  • tlk1 Protein
  • wu:fb76h12 Protein
  • wu:fe11e12 Protein

Bezeichner auf Proteinebene für Tousled-Like Kinase 1 Proteine (TLK1)

tousled-like kinase 1 , pKU-beta protein kinase , serine/threonine-protein kinase tousled-like 1-B , tousled-like kinase 1-B , SNARE protein kinase SNAK , serine threonine protein kinase , serine/threonine-protein kinase tousled-like 1

GENE ID SPEZIES
281533 Bos taurus
326734 Danio rerio
429024 Gallus gallus
459729 Pan troglodytes
478795 Canis lupus familiaris
537517 Bos taurus
542181 Zea mays
100024843 Monodelphis domestica
100052963 Equus caballus
100144941 Xenopus (Silurana) tropicalis
100157412 Sus scrofa
100174001 Pongo abelii
100345497 Oryctolagus cuniculus
100554902 Anolis carolinensis
100591136 Nomascus leucogenys
176369 Caenorhabditis elegans
9874 Homo sapiens
228012 Mus musculus
311118 Rattus norvegicus
557765 Danio rerio
Ausgewählte Anbieter für Tousled-Like Kinase 1 Proteine (TLK1)
Haben Sie etwas anderes gesucht?