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TSLP encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. Zusätzlich bieten wir Ihnen Thymic Stromal Lymphopoietin Kits (77) und Thymic Stromal Lymphopoietin Proteine (43) und viele weitere Produktgruppen zu diesem Protein an.
Showing 10 out of 193 products:
Human Polyclonal TSLP Primary Antibody für IHC (p), IHC - ABIN258389
Levin, Koelling, Friend, Isaksen, Ziegler, Perlmutter, Farr: Thymic stromal lymphopoietin: a cytokine that promotes the development of IgM+ B cells in vitro and signals via a novel mechanism. in Journal of immunology (Baltimore, Md. : 1950) 1999
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Human Polyclonal TSLP Primary Antibody für ELISA, ICC - ABIN258390
Quentmeier, Drexler, Fleckenstein, Zaborski, Armstrong, Sims, Lyman: Cloning of human thymic stromal lymphopoietin (TSLP) and signaling mechanisms leading to proliferation. in Leukemia 2001
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Human Polyclonal TSLP Primary Antibody für IHC (p), ELISA - ABIN2476988
Liu, Soumelis, Watanabe, Ito, Wang, Malefyt, Omori, Zhou, Ziegler: TSLP: an epithelial cell cytokine that regulates T cell differentiation by conditioning dendritic cell maturation. in Annual review of immunology 2007
Mouse (Murine) Polyclonal TSLP Primary Antibody für ELISA, ICC - ABIN4363149
Caglayan Sozmen, Karaman, Cilaker Micili, Isik, Arikan Ayyildiz, Bagriyanik, Uzuner, Karaman: Resveratrol ameliorates 2,4-dinitrofluorobenzene-induced atopic dermatitis-like lesions through effects on the epithelium. in PeerJ 2016
Human Polyclonal TSLP Primary Antibody für IHC, ELISA - ABIN1583450
Sato-Deguchi, Imafuku, Chou, Ishii, Hiromatsu, Nakayama: Topical vitamin D₃ analogues induce thymic stromal lymphopoietin and cathelicidin in psoriatic skin lesions. in The British journal of dermatology 2012
Human Polyclonal TSLP Primary Antibody für IF (p), IHC (p) - ABIN668766
Sakitani, Nonaka, Shibata, Furukawa, Yoshihara: Increased Expression of Thymic Stromal Lymphopoietin and Its Receptor in Kimura's Disease. in ORL; journal for oto-rhino-laryngology and its related specialties 2015
The results suggest that IL-1beta (zeige IL1B Antikörper) may be an early key mediator for the acquisition of an Atopic dermatitis (AD) phenotype through induction of thymic stromal lymphopoietin (TSLP) and alteration of the epidermal homeostasis.
House dust mite exposure increases the expression of TSLP through PI3K/Akt signalin (zeige CDH1 Antikörper)g pathway in human bronc (zeige HDAC3 Antikörper)hial epithelial 16HBE cells.
Posttranslational modifications control the functional activity of TSLP in humans and overproduction of TSLP may be a key trigger for the amplification of type 2 inflammation in diseases
Study provides evidence for the hypothesis that TSLP could reflect the histological severity of lumbar disc degeneration (LDD), and TSLP-siRNA and TSLPR (zeige CRLF2 Antikörper)-siRNA could inhibit apoptosis of nucleus pulposus cells. The evident information obtained from the investigation could lead the way for new therapeutic approaches regarding LDD treatment.
periostin (zeige POSTN Antikörper)-mediated TSLP production by keratinocytes directly stimulates cutaneous T-cell lymphoma (CTCL) tumor (zeige EEF1A1 Antikörper) cell growth in addition to inducing a Th2-dominant tumor environment in CTCL (zeige TSPYL2 Antikörper).
this study shows that TSLP may be involved in the pathogenesis of asthma and rhinitis; dust mite and mugwort allergy could increase it significantly
Serum TSLP levels were significantly increased in systemic sclerosis patients compared to healthy donors, and were associated with a higher frequency of vasculopathy. The proportion of TSLP-positive dermal cells was increased in the skin of SSc (zeige CYP11A1 Antikörper) patients compared with healthy donors, and was correlated with fibrosis.
this study shows that NOD2 (zeige NOD2 Antikörper) is an asthma-related factor that can promote cell proliferation and inflammatory response by mediated expression of TSLP in human airway smooth muscle cells
the effects of TSLP on myeloid cells are crucial in reducing the multiple organ failure that is associated with systemic inflammation.
interactions between TSLP in follicular dendritic cells and IgA production in tonsils may be an important mechanism contributing to the pathogenesis of Immunoglobulin A (IgA) nephropathy.
study concludes that IL-33 (zeige IL33 Antikörper) and TSLP are required for epithelial cell IL-25 (zeige IL25 Antikörper) expression, mucous metaplasia, and ILC2 expansion following early-life rhinovirus infection
TSLP plays a role in dysfunction of airway epithelial adherens junctions E-cadherin (zeige CDH1 Antikörper) in house dust mite (HDM (zeige HDAC3 Antikörper))-induced asthma. Mice treated with an anti-TSLP mAb ameliorated airway inflammation, the decreasing and aberrant distribution of E-cadherin (zeige CDH1 Antikörper) and beta-catenin (zeige CTNNB1 Antikörper) as well as phosphorylation(p)-AKT (zeige AKT1 Antikörper) induced by HDM (zeige HDAC3 Antikörper). In vitro, HDM (zeige HDAC3 Antikörper) increased the expression of TSLP and E-cadherin (zeige CDH1 Antikörper) dysfunction by PI3K/Akt (zeige AKT1 Antikörper) signaling pathway.
this study shows that TSLP is a key target of Mi-2beta (zeige CHD4 Antikörper) in keratinocytes, and that loss of TSLP signaling in regulatory T cells prevents their activation
These data demonstrate that multiple pathogenic strains of RSV induce IL-13 (zeige IL13 Antikörper)-producing group 2 innate lymphoid cell proliferation and activation through a TSLP-dependent mechanism in a murine model and suggest the potential therapeutic targeting of TSLP during severe RSV infection.
The inflammatory phenotype in barrier-defective skin is shaped by counterregulation between the TSLP/type 2 and IL-23 (zeige IL23A Antikörper)/type 17 axes.
this study shows that activation of primed TH2 cells occurs independently of group 2 innate lymphoid cells or their cytokines but that the effector function of both cell types was dependent on combinatorial exposure to IL-33 (zeige IL33 Antikörper), IL-25 (zeige IL25 Antikörper) and TSLP
TNF-alpha (zeige TNF Antikörper) and IL-1beta (zeige IL1B Antikörper), which are partly produced by LPS (zeige TLR4 Antikörper)-activated leukocytes, contribute to TSLP production via TLR4 (zeige TLR4 Antikörper) activation in vivo.
IL-33 (zeige IL33 Antikörper)-ERK (zeige EPHB2 Antikörper)/JNK (zeige MAPK8 Antikörper)/p38 (zeige CRK Antikörper)/Egr-1 (zeige EGR1 Antikörper)/TSLP axis involved in allergic skin Th2 inflammation
Suggest that TSLP may be involved in acute lung injury, and blockage of TSLP signaling using TSLPR (zeige CRLF2 Antikörper)-Ig improves ALI at least in part by regulation of dendritic cell functions.
This gene encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells. The protein promotes T helper type 2 (TH2) cell responses that are associated with immunity in various inflammatory diseases, including asthma, allergic inflammation and chronic obstructive pulmonary disease. The protein is therefore considered a potential therapeutic target for the treatment of such diseases. Alternative splicing of this gene results in multiple transcript variants.
thymic stromal lymphopoietin
, thymic stromal lymphopoetin
, thymic stroma-derived lymphopoietin