anti-Thrombomodulin (THBD) Antikörper

The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. Zusätzlich bieten wir Ihnen Thrombomodulin Kits (98) und Thrombomodulin Proteine (25) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
THBD 7056 P07204
THBD 21824 P15306
THBD 83580  
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Top anti-Thrombomodulin Antikörper auf antikoerper-online.de

Showing 10 out of 267 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Maus PE FACS Detection of Thrombomodulin/BDCA-3 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human Thrombomodulin/BDCA-3 PE-conjugated Monoclonal Antibody. Quadrant markers were set based on internal control antibody staining. 25 Tests Anmelden zum Anzeigen 8 bis 9 Tage
$195.50
Details
Maus Ratte PE FACS Detection of Thrombomodulin/BDCA-3 in bEnd.3 Mouse Cell Line by Flow Cytometry. bEnd.3 mouse endothelioma cell line was stained with Rat Anti-Mouse Thrombomodulin/BDCA-3 PE-conjugated Monoclonal Antibody. 100 Tests Anmelden zum Anzeigen 8 bis 9 Tage
$334.65
Details
Maus Ratte Unkonjugiert CyTOF, FACS, ICC, IHC, WB Detection of Thrombomodulin/BDCA-3 in bEnd.3 Mouse Cell Line by Flow Cytometry. bEnd.3 mouse endothelioma cell line was stained with Mouse Thrombomodulin/BDCA-3 Monoclonal Antibody. Thrombomodulin/BDCA-3 in bEnd.3 Mouse Cell Line. Thrombomodulin/BDCA-3 was detected in immersion fixed bEnd.3 mouse endothelioma cell line using Mouse Thrombomodulin/BDCA-3 Monoclonal Antibody  at 10 ug/mL for 3 hours at room temperature. Cells were stained using the NorthernLightsル 557-conjugated Anti-Rat IgG Secondary Antibody (red 100 μg Anmelden zum Anzeigen 8 bis 9 Tage
$299.00
Details
Maus Ziege Unkonjugiert CyTOF, FACS, ICC, IP, WB Thrombomodulin/BDCA-3 in bEnd.3 Mouse Cell Line. Thrombomodulin/BDCA-3 was detected in immersion fixed bEnd.3 mouse endothelioma cell line using Goat Anti-Mouse Thrombomodulin/BDCA-3 Antigen Affinity-purified Polyclonal Antibody. Specific staining was localized to cytoplasm. 100 μg Anmelden zum Anzeigen 8 bis 9 Tage
$416.30
Details
Human Kaninchen Unkonjugiert ELISA, WB   100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Maus FITC FACS 1 mL Anmelden zum Anzeigen 6 bis 8 Tage
$308.00
Details
Human Maus Unkonjugiert FACS 2 mL Anmelden zum Anzeigen 6 bis 8 Tage
$286.00
Details
Human Maus Unkonjugiert IHC (fro), FACS, IF, IHC (p)   1 mL Anmelden zum Anzeigen 11 bis 13 Tage
$619.85
Details
Maus Ratte Fluorescein FACS Detection of Thrombomodulin/BDCA-3 in bEnd.3 Mouse Cell Line by Flow Cytometry. bEnd.3 mouse endothelioma cell line was stained with Rat Anti-Mouse Thrombomodulin/BDCA-3 Fluorescein-conjugated Monoclonal Antibody. 100 Tests Anmelden zum Anzeigen 8 bis 9 Tage
$270.25
Details
Maus Ratte APC FACS Detection of Thrombomodulin/BDCA-3 in bEnd.3 Mouse Cell Line by Flow Cytometry. bEnd.3 mouse endothelioma cell line was stained with Rat Anti-Mouse Thrombomodulin/BDCA-3 APC-conjugated Monoclonal Antibody. 100 Tests Anmelden zum Anzeigen 8 bis 9 Tage
$387.55
Details

THBD Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-Thrombomodulin Antikörper

  1. Human Polyclonal Thrombomodulin Primary Antibody für WB - ABIN2801892 : Suzuki, Kusumoto, Deyashiki, Nishioka, Maruyama, Zushi, Kawahara, Honda, Yamamoto, Horiguchi: Structure and expression of human thrombomodulin, a thrombin receptor on endothelium acting as a cofactor for protein C activation. in The EMBO journal 1987 (PubMed)
    Show all 5 Pubmed References

  2. Human Monoclonal Thrombomodulin Primary Antibody für FACS, WB - ABIN2192010 : Dömötör, Benzakour, Griffin, Yule, Fukudome, Zlokovic: Activated protein C alters cytosolic calcium flux in human brain endothelium via binding to endothelial protein C receptor and activation of protease activated receptor-1. in Blood 2003 (PubMed)
    Show all 3 Pubmed References

  3. Mouse (Murine) Polyclonal Thrombomodulin Primary Antibody für CyTOF, FACS - ABIN4899312 : Schmidt, Yang, Janssen, Gandjeva, Perez, Barthel, Zemans, Bowman, Koyanagi, Yunt, Smith, Cheng, Overdier, Thompson, Geraci, Douglas, Pearse, Tuder: The pulmonary endothelial glycocalyx regulates neutrophil adhesion and lung injury during experimental sepsis. in Nature medicine 2013 (PubMed)
    Show all 3 Pubmed References

  4. Human Monoclonal Thrombomodulin Primary Antibody für WB - ABIN2192009 : Tsuneyoshi, Fukudome, Higuchi, Kimoto: Preparation and characterization of monoclonal antibodies to thrombomodulin. in Hybridoma (2005) 2005 (PubMed)
    Show all 2 Pubmed References

  5. Human Monoclonal Thrombomodulin Primary Antibody für IHC (fro), FACS - ABIN2478498 : Drake, Loke: Isolation of endothelial cells from human first trimester decidua using immunomagnetic beads. in Human reproduction (Oxford, England) 1992 (PubMed)
    Show all 4 Pubmed References

  6. Human Monoclonal Thrombomodulin Primary Antibody für FACS - ABIN4896076 : Silk, Silk, Ichiryu, Davies, Nolan, Leishman, Carpenter, Watt, Cerundolo, Fairchild: Cross-presentation of tumour antigens by human induced pluripotent stem cell-derived CD141(+)XCR1+ dendritic cells. in Gene therapy 2012 (PubMed)

  7. Human Monoclonal Thrombomodulin Primary Antibody für FM, IHC (fro) - ABIN2688974 : Teasdale, Bird, Bird: Internalization of the anticoagulant thrombomodulin is constitutive and does not require a signal in the cytoplasmic domain. in Immunology and cell biology 1995 (PubMed)

  8. Mouse (Murine) Monoclonal Thrombomodulin Primary Antibody für FACS - ABIN4895906 : Geiger, Pawar, Kerschen, Nattamai, Hernandez, Liang, Fernández, Cancelas, Ryan, Kustikova, Schambach, Fu, Wang, Fink, Petersen, Zhou, Griffin, Baum, Weiler, Hauer-Jensen: Pharmacological targeting of the thrombomodulin-activated protein C pathway mitigates radiation toxicity. in Nature medicine 2012 (PubMed)

  9. Mouse (Murine) Monoclonal Thrombomodulin Primary Antibody für CyTOF, FACS - ABIN4899313 : Belcher, Chen, Nguyen, Milbauer, Abdulla, Alayash, Smith, Nath, Hebbel, Vercellotti: Heme triggers TLR4 signaling leading to endothelial cell activation and vaso-occlusion in murine sickle cell disease. in Blood 2014 (PubMed)

Weitere Antikörper gegen Thrombomodulin Interaktionspartner

Human Thrombomodulin (THBD) Interaktionspartner

  1. TM, especially TME45, maintains vascular integrity, at least in part, via Src (zeige SRC Antikörper) signaling.

  2. The present study found that the fifth epidermal growth factor (zeige EGF Antikörper)-like domain of thrombomodulin (TME5) possesses the cytoprotective function in association with an increase in levels of anti-apoptotic myeloid cell leukemia-1 protein in an activated protein C (zeige PROC Antikörper)-independent

  3. Case Report: CD141+ myeloid dentritic cell differentiation of a juvenile myelomonocytic leukemia.

  4. The finding of a previously unrecognized fibrinolytic phenotype indicates that bleeding in Thrombomodulin-associated coagulopathy has a complex pathogenesis and highlights the pivotal role of TM as a regulator of hemostasis.

  5. TM mediates cell proliferation and migration via the Epithelial-To-Mesenchymal Transition (EMT (zeige ITK Antikörper)) biomarkercyclooxygenase (COX)-2 (zeige COX2 Antikörper)

  6. the whole THBD gene sequenced in patients with recurrent venous thromboembolism (VTE); found 8 polymorphisms in the THBD gene in Swedish population; none of these polymorphisms was significantly associated with the risk of VTE recurrence; results indicate that THBD polymorphisms may not be a risk factor for VTE recurrence

  7. CORM-2 protects human umbilical vein endothelial cells from lipopolysaccharide-induced injury, by way of suppressing NF-kappaB (zeige NFKB1 Antikörper) activity, which downregulates TM and EPCR (zeige PROCR Antikörper) mRNAs. It also decreases MMP-2 (zeige MMP2 Antikörper) expression and prevents the shedding of TM and EPCR (zeige PROCR Antikörper) from the surface of endothelial cells, so as to preserve their protective effect.

  8. The results demonstrate that the LFA-1 (zeige ITGAL Antikörper) and Mac-1 (zeige ITGAM Antikörper) integrins on leukocytes bind to thrombomodulin (TM), thereby establishing the molecular and structural basis underlying LFA-1 (zeige ITGAL Antikörper) and Mac-1 (zeige ITGAM Antikörper) integrin interaction with TM on endothelial cells.

  9. Human thrombomodulin transgenic aortic endothelial cells are less sensitive to activation by either HMGB1 or hTNFalpha, an effect that appears to be dependent on the lectin-like domain of TBM.

  10. In placenta of patients with preeclampsia, we detected abnormal expression of F3 and THBD with increased protein and mRNA levels. The role of these molecules in the pathogenesis of this disease and in alterations of hemostatic and histopathological aspects of placentas need further studying.

Mouse (Murine) Thrombomodulin (THBD) Interaktionspartner

  1. discovery of a novel physiological function of thrombomodulin-dependent activated protein C (zeige PROC Antikörper) generation within the CNS

  2. The present study found that the fifth epidermal growth factor (zeige EGF Antikörper)-like domain of thrombomodulin (TME5) possesses the cytoprotective function in association with an increase in levels of anti-apoptotic myeloid cell leukemia-1 protein in an activated protein C (zeige PROC Antikörper)-independent

  3. the lectin-like domain of thrombomodulin is critically involved in host defence against E. coli induced acute pyelonephritis

  4. Identified Nur77 (zeige NR4A1 Antikörper)/Nor1 (zeige NR4A3 Antikörper) as novel regulators of thrombomodulin expression and function in vascular endothelial cells.

  5. TM expression in corneal epithelium was modulated during the corneal wound healing process, and may be regulated by PDGF (zeige PDGFA Antikörper)-BB. In addition, rTMD23 has therapeutic potential in corneal injury

  6. Thrombomodulin contributes to gamma tocotrienol-mediated lethality protection and hematopoietic cell recovery in irradiated mice

  7. the recombinant epidermal growth factor (zeige EGF Antikörper)-like domain plus serine/threonine-rich domain of thrombomodulin suppresses the inflammatory response in mice

  8. Thrombomodulin may modulate allergic responses by inhibiting the activation of both eosinophils and mast cells.

  9. Thrombomodulin modulates dendritic cells via both antagonism of high mobility group protein B1 (zeige HMGB1 Antikörper) and an independent mechanism.

  10. The lectin-like domain of TM does not play an important role in the host response to M. tuberculosis infection in mice.

Rabbit Thrombomodulin (THBD) Interaktionspartner

  1. Atorvastin induces THBD expression in the aorta of cholesterol-fed rabbits.

Thrombomodulin (THBD) Antigen-Profil

Protein Überblick

The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia.

Genbezeichner und Symbole assoziert mit anti-Thrombomodulin (THBD) Antikörper

  • thrombomodulin (THBD) Antikörper
  • thrombomodulin (Thbd) Antikörper
  • AHUS6 Antikörper
  • AI385582 Antikörper
  • BDCA3 Antikörper
  • CD141 Antikörper
  • THBD Antikörper
  • THPH12 Antikörper
  • THRM Antikörper
  • TM Antikörper

Bezeichner auf Proteinebene für anti-Thrombomodulin (THBD) Antikörper

thrombomodulin , CD141 antigen , fetomodulin , snoRNA MBII-339 , thrombomdulin , TM

GENE ID SPEZIES
469898 Pan troglodytes
702132 Macaca mulatta
100049012 Felis catus
7056 Homo sapiens
474355 Canis lupus familiaris
21824 Mus musculus
83580 Rattus norvegicus
100157642 Sus scrofa
100008887 Oryctolagus cuniculus
100723479 Cavia porcellus
281529 Bos taurus
428546 Gallus gallus
101103256 Ovis aries
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