Solute Carrier Organic Anion Transporter Family, Member 1B1 Proteine (SLCO1B1)

SLCO1B1 encodes a liver-specific member of the organic anion transporter family. Zusätzlich bieten wir Ihnen SLCO1B1 Antikörper (40) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
SLCO1B1 10599 Q9Y6L6
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Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 46 Days
5.173,33 €
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HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
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SLCO1B1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,
, ,

Weitere Proteine zu Solute Carrier Organic Anion Transporter Family, Member 1B1 (SLCO1B1) Interaktionspartnern

Human Solute Carrier Organic Anion Transporter Family, Member 1B1 (SLCO1B1) Interaktionspartner

  1. SLCO1B1 polymorphisms appear to be associated with the development of adverse drug reactions to regorafenib.

  2. Polymorphisms in SLCO1B1 and UGT1A1 (zeige UGT1A1 Proteine) are associated with several different sorafenib side effects

  3. OATP1A2, OATP1B1, and OATP2B1 (zeige SLCO2B1 Proteine) can mediate cellular uptake of ochratoxin A, which could aggravate OTA toxicity.

  4. Our results did not indicate a strong association between OATP1B1 or OATP1B3 inhibition and hyperbilirubinemia

  5. Polymorphisms of the SLCO1B1 gene ate used for predicting risk of adverse events when using statins.

  6. Critical amino acid residues in the predicted transmembrane pore influencing transport kinetics of the hepatic drug transporter OATP1B1 have been identified.

  7. Genetic polymorphisms of the UGT1A1 (zeige UGT1A1 Proteine) promoter, specifically the T-3279G phenobarbital-responsive enhancer module and (TA)7 dinucleotide repeat, as well as the intron and coding region variants of the OATP2, HMOX1 (zeige HMOX1 Proteine), and BLVRA (zeige BLVRA Proteine) genes, were significantly higher among the cases than the controls.

  8. SLCO1B1 genotype was not associated with the risk of statin-associated muscle symptoms.

  9. these findings demonstrate an important role for OATP1B1 in the systemic pharmacokinetics of multiple drugs used in the treatment of acute myeloid leukemia (zeige BCL11A Proteine)

  10. Genetic link with cholelithiasis among pediatric SCA Tunisian patients: Examples of UGT1A1 (zeige UGT1A1 Proteine), SLCO1A2 and SLCO1B1.

SLCO1B1 Protein Überblick

Protein Überblick

This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of numerous endogenous compounds including bilirubin, 17-beta-glucuronosyl estradiol and leukotriene C4. This protein is also involved in the removal of drug compounds such as statins, bromosulfophthalein and rifampin from the blood into the hepatocytes. Polymorphisms in the gene encoding this protein are associated with impaired transporter function.

Genbezeichner und Symbole assoziert mit SLCO1B1

  • solute carrier organic anion transporter family, member 1B1 (SLCO1B1)
  • HBLRR Protein
  • LST-1 Protein
  • LST1 Protein
  • OATP-C Protein
  • OATP1B1 Protein
  • OATP2 Protein
  • OATPC Protein
  • SLC21A6 Protein
  • SLCO1B1 Protein

Bezeichner auf Proteinebene für SLCO1B1

OATP-2 , liver-specific organic anion transporter 1 , sodium-independent organic anion-transporting polypeptide 2 , solute carrier family 21 (organic anion transporter), member 6 , solute carrier family 21 member 6 , solute carrier organic anion transporter family member 1B1 , solute carrier organic anion transporter family, member 1B1 , solute carrier organic anion transporter family member 1B1-like

GENE ID SPEZIES
10599 Homo sapiens
465331 Pan troglodytes
705308 Macaca mulatta
100011628 Monodelphis domestica
100448597 Pongo abelii
100585039 Nomascus leucogenys
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