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SLCO1B1 Produkte

(Solute Carrier Organic Anion Transporter Family, Member 1B1, SLCO1B1)

Kategorien

This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of numerous endogenous compounds including bilirubin, 17-beta-glucuronosyl estradiol and leukotriene C4. This protein is also involved in the removal of drug compounds such as statins, bromosulfophthalein and rifampin from the blood into the hepatocytes. Polymorphisms in the gene encoding this protein are associated with impaired transporter function. [provided by RefSeq, Mar 2009].

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Ausgewählte SLCO1B1 Kategorien

SLCO1B1 Antikörper

High quality antibodies with extensive validation data.

SLCO1B1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene SLCO1B1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
ReaktivitätHuman, Mouse
ApplikationELISA, ICC, IF, WB
Validierungen
  • collections(3)
Kat. Nr.ABIN6257509
Menge100 μL
ReaktivitätHuman
ApplikationWB
Validierungen
  • collections(2)
Kat. Nr.ABIN653562
Menge400 μL
ReaktivitätHuman
ApplikationELISA, WB
Validierungen
  • collections(1)
Kat. Nr.ABIN3185986
Menge100 μL

Empfohlene SLCO1B1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
ReaktivitätHuman
SourceInsect Cells
Validierungen
  • collections(1)
Kat. Nr.ABIN3077187
Menge1 mg
ReaktivitätHuman
SourceInsect Cells
Validierungen
  • collections(1)
Kat. Nr.ABIN3095558
Menge0.5 mg
ReaktivitätHuman
SourceWheat germ
Validierungen
  • collections(1)
Kat. Nr.ABIN1320553
Menge10 μg

Neueste Publikationen zu unseren SLCO1B1 Produkten

Green, Kaipainen, Bullock, Zhang, Lucas, Matson, Banks, Mostaghel: "Role of OATP transporters in steroid uptake by prostate cancer cells in vivo." in: Prostate cancer and prostatic diseases, 2016 (PubMed).

Hogg, Thomas, Ashford, Cartwright, Coldwell, Weston, Pillmoor, Surry, OToole: "Quantification of proteins by flow cytometry: Quantification of human hepatic transporter P-gp and OATP1B1 using flow cytometry and mass spectrometry." in: Methods (San Diego, Calif.), Vol. 82, pp. 38-46, 2015 (PubMed). (Probematerial (Species): Human). Weitere Details: Flow Cytometry

Ramsey, Bruun, Yang, Treviño, Vattathil, Scheet, Cheng, Rosner, Giacomini, Fan, Sparreboom, Mikkelsen, Corydon, Pui, Evans, Relling: "Rare versus common variants in pharmacogenetics: SLCO1B1 variation and methotrexate disposition." in: Genome research, Vol. 22, Issue 1, pp. 1-8, 2012 (PubMed).

Leuthold, Hagenbuch, Mohebbi, Wagner, Meier, Stieger: "Mechanisms of pH-gradient driven transport mediated by organic anion polypeptide transporters." in: American journal of physiology. Cell physiology, Vol. 296, Issue 3, pp. C570-82, 2009 (PubMed).

Yamaguchi, Okada, Akitaya, Ohara, Mikkaichi, Ishikawa, Sato, Matsuura, Saga, Unno, Abe, Mano, Hishinuma, Goto: "Transport of fluorescent chenodeoxycholic acid via the human organic anion transporters OATP1B1 and OATP1B3." in: Journal of lipid research, Vol. 47, Issue 6, pp. 1196-202, 2006 (PubMed). Weitere Details: Western Blotting

Cui, König, Nies, Pfannschmidt, Hergt, Franke, Alt, Moll, Keppler: "Detection of the human organic anion transporters SLC21A6 (OATP2) and SLC21A8 (OATP8) in liver and hepatocellular carcinoma." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 83, Issue 4, pp. 527-38, 2003 (PubMed).

Synonyme und alternative Namen zu SLCO1B1

solute carrier organic anion transporter family member 1B1 (SLCO1B1), solute carrier organic anion transporter family member 1B1 (LOC100011628), solute carrier organic anion transporter family member 1B1 (LOC100448597), HBLRR, LST-1, LST1, OATP-C, OATP1B1, OATP2, OATPC, SLC21A6, SLCO1B1

Gen-IDs für verschiedene Spezies

GENE ID SPEZIES
10599 Homo sapiens
465331 Pan troglodytes
705308 Macaca mulatta
100011628 Monodelphis domestica
100448597 Pongo abelii
100585039 Nomascus leucogenys

Bezeichner auf Proteinebene für SLCO1B1

  • OATP-2
  • liver-specific organic anion transporter 1
  • sodium-independent organic anion-transporting polypeptide 2
  • solute carrier family 21 (organic anion transporter), member 6
  • solute carrier family 21 member 6
  • solute carrier organic anion transporter family member 1B1
  • solute carrier organic anion transporter family, member 1B1
  • solute carrier organic anion transporter family member 1B1-like
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