Sirtuin 3 Proteine (SIRT3)

SIRT3 encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Zusätzlich bieten wir Ihnen SIRT3 Antikörper (235) und SIRT3 Kits (26) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
SIRT3 23410 Q9NTG7
SIRT3 64384 Q8R104
SIRT3 293615  
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Top SIRT3 Proteine auf antikoerper-online.de

Showing 10 out of 14 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Wheat germ Human GST tag 2 μg Anmelden zum Anzeigen 11 bis 12 Tage
$333.33
Details
Escherichia coli (E. coli) Human His tag 50 μg Anmelden zum Anzeigen 15 bis 19 Tage
$319.00
Details
Escherichia coli (E. coli) Ratte His tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$701.00
Details
Escherichia coli (E. coli) Human His tag Validation with Western Blot 50 μg Anmelden zum Anzeigen 10 bis 12 Tage
$229.85
Details
Escherichia coli (E. coli) Human His tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$560.00
Details
Escherichia coli (E. coli) Human Unkonjugiert   50 μg Anmelden zum Anzeigen 2 bis 3 Tage
$364.64
Details
Baculovirus infected Insect Cells Human GST tag   5 μg Anmelden zum Anzeigen 10 bis 12 Tage
$365.64
Details
Escherichia coli (E. coli) Maus His tag,T7 tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$656.00
Details
Escherichia coli (E. coli) Huhn Unkonjugiert   5 applications Anmelden zum Anzeigen 1 bis 2 Tage
$312.71
Details
Escherichia coli (E. coli) Ratte Unkonjugiert   100 μg Anmelden zum Anzeigen 11 bis 18 Tage
$893.75
Details

SIRT3 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
,
Mouse (Murine)

Rat (Rattus)

Am meisten referenzierte SIRT3 Proteine

  1. Human SIRT3 Protein expressed in Wheat germ - ABIN1320045 : Pacella-Ince, Zander-Fox, Lan: Mitochondrial SIRT3 and its target glutamate dehydrogenase are altered in follicular cells of women with reduced ovarian reserve or advanced maternal age. in Human reproduction (Oxford, England) 2014 (PubMed)

Weitere Proteine zu Sirtuin 3 (SIRT3) Interaktionspartnern

Human Sirtuin 3 (SIRT3) Interaktionspartner

  1. survival curves showed that higher SIRT3 expression is correlated to a poorer prognosis for patients with grade 3 breast cancer. In conclusion, SIRT3 could be a therapeutic target for breast cancer, improving the effectiveness of CDDP and TAM (zeige CCNA1 Proteine) treatments.

  2. There were no significant correlations between LRP130, SIRT3, or PGC-1alpha mRNA expression in response to acute sprint-interval training. Changes in protein expression of LRP130, SIRT3, and PGC-1alpha were positively correlated at several time points with large effect sizes, which suggest that the regulation of these proteins may be coordinated in human skeletal muscle.

  3. In human myometrium, SIRT3 expression decreases with term labor and regulates the mediators involved in the terminal effector pathways of human labor and delivery through the NFkappaB1 pathway.

  4. Mitochondria-targeted esculetin has anti-atherosclerotic effects by inhibiting PAI-1 (zeige SERPINE1 Proteine) levels by modulating miR (zeige MLXIP Proteine)-19b and -30c expression and affecting SIRT3- and STAT3 (zeige STAT3 Proteine)-mediated signaling pathways.

  5. the activation of the SIRT3 axis of the UPRmt is linked to metastasis.

  6. these results suggest a potential relationship between SIRT3 enzymatic activity, IDH2 (zeige IDH2 Proteine)-K413 acetylation-determined dimerization, and a cancer-permissive phenotype

  7. These data suggest a novel role for SIRT3 deficiency in mediating alveolar epithelial cell mtDNA damage, apoptosis, and lung fibrosis.-

  8. Data suggested a protective role of the SIRT3 single-nucleotide polymorphism rs4980329 in ALS risk.

  9. Low SIRT3 expression is associated with metastasis and epithelial-mesenchymal transition in hepatocellular carcinoma.

  10. Low SIRT3 expression is associated with Prostate Cancer.

Mouse (Murine) Sirtuin 3 (SIRT3) Interaktionspartner

  1. Sirtuin 3 is required for osteogenic differentiation through maintenance of PGC (zeige PGC Proteine)-1a-SOD2 (zeige SOD2 Proteine)-mediated regulation of mitochondrial function

  2. findings reveal an unexpected mechanism for SIRT3 regulation via SIRT1 (zeige SIRT1 Proteine)-mediated deacetylation. Improving mitochondrial SIRT3 functions by inhibiting SIRT3 acetylation may offer a new therapeutic approach for obesity- and aging-related diseases associated with mitochondrial dysfunction.

  3. Sirt3 expression in bone marrow cells increases during aging, suggesting that Sirt3 promotes age-related adipogenesis and osteoclastogenesis associated with bone loss. These findings identify Sirt3 as an important regulator of adipogenesis and skeletal homeostasis in vivo and identify Sirt3 as a potential target for the treatment of osteoporosis.

  4. These data suggest a novel role for SIRT3 deficiency in mediating alveolar epithelial cell mtDNA damage, apoptosis, and lung fibrosis.-

  5. Diminished Sirt3 expression and redox inactivation of Sirt3 led to SOD2 (zeige SOD2 Proteine) inactivation and contributes to hypertension.

  6. Data suggest that negative regulatory effect of Sirt3 on Nlrp3 (zeige NLRP3 Proteine) inflammasome assembly in macrophages due to prolonged fasting occurs via Sirt3-mediated deacetylation of mitochondrial Sod2 (zeige SOD2 Proteine), leading to Sod2 (zeige SOD2 Proteine) activation; prolonged fasting blunts inflammasomes in wild-type mice but not in Sirt3 knock-out mice. (Sirt3 = sirtuin 3; Nlrp3 (zeige NLRP3 Proteine) = NLR (zeige CXCR5 Proteine) family, pyrin domain containing 3 protein; Sod2 (zeige SOD2 Proteine) = superoxide dismutase 2 (zeige SOD2 Proteine))

  7. Results reveal a potential mechanism by which SIRT3 deletion exacerbates post-MI cardiac dysfunction and impairment of cardiac recovery involving microvascular rarefaction and pre-existing coronary microvascular dysfunction.

  8. expression and activity of the NADase CD38 increase with aging and that CD38 is required for the age-related NAD decline and mitochondrial dysfunction via a pathway mediated at least in part by regulation of SIRT3 activity.

  9. Data show that resveratrol reduced mitochondrial reactive oxygen species (mROS) generation by promoting Sirt3 enrichment within the mitochondria and subsequent upregulation of FoxO3a (zeige FOXO3 Proteine)-mediated mitochondria gene expression of PGC-1alpha and SOD2 (zeige SOD2 Proteine).

  10. These data demonstrate a critical role of SIRT3 in the control of myofibroblast differentiation and lung fibrosis.

Cow (Bovine) Sirtuin 3 (SIRT3) Interaktionspartner

  1. The results indicate that the polymorphisms in transcription factor binding sites of SIRT3 promoter may affect the transcriptional activity of SIRT3, and thus alter intramuscular fat content in beef cattle.

  2. The results indicate that the variations in the class I sirtuin (zeige SIRT1 Proteine) genes and their corresponding genotypes may be considered as molecular markers for economic traits in cattle breeding.

  3. The expression profile of sirtuin 1 (zeige SIRT1 Proteine) and sirtuin 3 in the liver, muscle, and adipose tissue of calves and bulls is reported.

SIRT3 Protein Überblick

Protein Überblick

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined\; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two alternatively spliced transcript variants that encode different proteins have been described for this gene.

Genbezeichner und Symbole assoziert mit Sirtuin 3 Proteine (SIRT3)

  • sirtuin 3 (sirt3)
  • sirtuin 3 (SIRT3)
  • sirtuin 3 (Sirt3)
  • 2310003L23Rik Protein
  • AI848213 Protein
  • Sir2l3 Protein
  • sirtuin Protein
  • zgc:158774 Protein

Bezeichner auf Proteinebene für Sirtuin 3 Proteine (SIRT3)

sirtuin 3 , sirtuin , NAD-dependent deacetylase sirtuin-3, mitochondrial , NAD-dependent protein deacetylase sirtuin-3, mitochondrial , SIR2-like protein 3 , mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase , regulatory protein SIR2 homolog 3 , silent mating type information regulation 2, S.cerevisiae, homolog 3 , sir2-like 3 , sirtuin type 3 , SIRT3 mitochondrial , NAD-dependent deacetylase sirtuin-3 , NAD-dependent protein deacetylase sirtuin-3 , SIRT3L mitochondrial , mSIR2L3 , mitochondrial protein lysine deacetylase , silent mating type information regulation 2, (S.cerevisiae, homolog)-like 3

GENE ID SPEZIES
558775 Danio rerio
100604320 Nomascus leucogenys
422988 Gallus gallus
23410 Homo sapiens
475933 Canis lupus familiaris
100354500 Oryctolagus cuniculus
64384 Mus musculus
293615 Rattus norvegicus
101087609 Felis catus
614027 Bos taurus
100125971 Sus scrofa
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