SUMO1 Activating Enzyme Subunit 2 (UBA2) ELISA Kits

Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. Zusätzlich bieten wir Ihnen SUMO1 Activating Enzyme Subunit 2 Antikörper (75) und SUMO1 Activating Enzyme Subunit 2 Proteine (5) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
UBA2 10054 Q9UBT2
Anti-Maus UBA2 UBA2 50995 Q9Z1F9
Anti-Ratte UBA2 UBA2 308508  
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Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human
  96 Tests Anmelden zum Anzeigen 6 bis 8 Tage
443,57 €
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Weitere ELISA Kits für SUMO1 Activating Enzyme Subunit 2 Interaktionspartner

Human SUMO1 Activating Enzyme Subunit 2 (UBA2) Interaktionspartner

  1. We propose that disturbance of the SUMOylation pathway, mediated by pathogenic variants in UBA2, is a novel mechanism for aplasia cutis congenita and other phenotypic abnormalities.

  2. Here, we show that hHR23A utilizes both the UBA2 and XPCB domains to form a stable complex with Vpr, linking Vpr directly to cellular DNA repair pathways and their probable exploitation by the virus.

  3. Data indicate the role of anti-SUMO activating enzyme SAE1 (zeige SAE1 ELISA Kits) and SAE2 (zeige RBBP8 ELISA Kits) antibody as marker of dermatomyositis.

  4. Data show that the SAE2 (zeige RBBP8 ELISA Kits) subunit of the small ubiquitin-like modifier (SUMO (zeige SUMO1 ELISA Kits)) E1 is autoSUMOylated at residue Lys (zeige LYZ ELISA Kits)-236, and SUMOylation was catalyzed by Ubc9 (zeige UBE2I ELISA Kits) at several additional Lys (zeige LYZ ELISA Kits) residues surrounding the catalytic Cys (zeige DNAJC5 ELISA Kits)-173 of SAE2 (zeige RBBP8 ELISA Kits).

  5. loss of SAE1 (zeige SAE1 ELISA Kits)/2 activity drives synthetic lethality with Myc (zeige MYC ELISA Kits); inactivation of SAE2 (zeige RBBP8 ELISA Kits) leads to mitotic catastrophe and cell death upon Myc (zeige MYC ELISA Kits) hyperactivation; findings in Myc (zeige MYC ELISA Kits)-high breast cancers suggest low tumor SAE1 (zeige SAE1 ELISA Kits) and SAE2 (zeige RBBP8 ELISA Kits) correlates metastasis-free survival

  6. The mammalian E1 subunits can be imported separately, identify nuclear localization signals (NLSs) in Aos1 and in Uba2, and demonstrate that their import is mediated by importin alpha/beta in vitro and in intact cells.

  7. structures of heterodimeric Sae1 (zeige SAE1 ELISA Kits)/Sae2 (zeige RBBP8 ELISA Kits)-Mg.ATP and Sae1 (zeige SAE1 ELISA Kits)/Sae2 (zeige RBBP8 ELISA Kits)-SUMO-1 (zeige SUMO1 ELISA Kits)-Mg.ATP complexes

  8. UBA2 stabilizes APOBEC3G by preventing ubiquitin chain elongation and proteasome-mediated proteolysis.

SUMO1 Activating Enzyme Subunit 2 (UBA2) Antigen-Profil

Beschreibung des Gens

Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1\; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 (MIM 613294) and UBA2 form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999

Genbezeichner und Symbole assoziert mit UBA2

  • SUMO1 activating enzyme subunit 2 (MICPUN_63834) Antikörper
  • SUMO1 activating enzyme subunit 2 (MICPUCDRAFT_36729) Antikörper
  • SUMO-activating enzyme subunit 2 (SAE2) Antikörper
  • ubiquitin-like modifier activating enzyme 2 (UBA2) Antikörper
  • ubiquitin-like modifier activating enzyme 2 (Uba2) Antikörper
  • ubiquitin-like modifier activating enzyme 2 (uba2) Antikörper
  • AA986091 Antikörper
  • Arx Antikörper
  • ATSAE2 Antikörper
  • EMB2764 Antikörper
  • EMBRYO DEFECTIVE 2764 Antikörper
  • F3K23.23 Antikörper
  • F3K23_23 Antikörper
  • sae2 Antikörper
  • sae2-B Antikörper
  • sae2b Antikörper
  • SUMO-activating enzyme 2 Antikörper
  • UBA1 Antikörper
  • uba2-a Antikörper
  • uba2-b Antikörper
  • Ubl1a2 Antikörper
  • uble1b Antikörper
  • uble1b-B Antikörper
  • wu:fi17g06 Antikörper
  • zgc:66354 Antikörper

Bezeichner auf Proteinebene für UBA2

SUMO1 activating enzyme subunit 2 , SUMO-1 activating enzyme subunit 2 , SUMO-activating enzyme subunit 2 , UBA2, ubiquitin-activating enzyme E1 homolog , anthracycline-associated resistance ARX , ubiquitin-like 1-activating enzyme E1B , Sumo-1 activating enzyme subunit 2 , ubiquitin-like 1 (sentrin) activating enzyme E1B , ubiquitin-like 1 (sentrin) activating enzyme subunit 2 , SUMO-activating enzyme subunit 2-A , SUMO-activating enzyme subunit 2-B , ubiquitin-like 1-activating enzyme E1B-A , ubiquitin-like 1-activating enzyme E1B-B , SUMO1 activating enzyme subunit 2b

GENE ID SPEZIES
8248549 Micromonas sp. RCC299
9689179 Micromonas pusilla CCMP1545
816686 Arabidopsis thaliana
10054 Homo sapiens
50995 Mus musculus
308508 Rattus norvegicus
476490 Canis lupus familiaris
399235 Xenopus laevis
406672 Danio rerio
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