anti-SUMO1 Activating Enzyme Subunit 1 (SAE1) Antikörper

Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1\; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. Zusätzlich bieten wir Ihnen SAE1 Proteine (19) und SAE1 Kits (11) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
SAE1 57514 Q2M1Z3
SAE1 56459 Q9R1T2
SAE1 308384 Q6AXQ0
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Top anti-SAE1 Antikörper auf antikoerper-online.de

Showing 10 out of 131 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-SAE1 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:1562500<br><b>Positive Control: </b>Hela cell lysate WB Suggested Anti-SAE1 <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500 <br /> Positive Control: Hela cell lysate <br /> SAE1 is supported by BioGPS gene expression data to be expressed in HeLa 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-SAE1 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>Human brain 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Human Kaninchen Unkonjugiert IHC (p), WB The AOS1 C-term Pab (ABIN389081) is used in Western blot to detect AOS1 in mouse heart tissue lysate. Western blot analysis of AOS1 (arrow) using rabbit polyclonal AOS1 Antibody (C-term) (ABIN389081). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the AOS1 gene (Lane 2) (Origene Technologies). 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Rind (Kuh) Kaninchen Unkonjugiert EIA, WB 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
495,00 €
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Schimpanse Kaninchen Unkonjugiert EIA, IF, IHC (p), WB 0.5 mg Anmelden zum Anzeigen 7 bis 9 Tage
561,00 €
Details
Human Ziege Unkonjugiert ELISA, WB ABIN185082 staining (1µg/ml) of Jurkat lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 100 μg Anmelden zum Anzeigen 3 bis 4 Tage
349,82 €
Details
Human Maus Unkonjugiert IF, WB Immunofluorescence of monoclonal antibody to SAE1 on HeLa cell (antibody concentration 10 µg/mL). SAE1 monoclonal antibody (M01), clone 1G4-1G5 Western Blot analysis of SAE1 expression in HeLa. 0.1 mg Anmelden zum Anzeigen 12 bis 16 Tage
454,76 €
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Rind (Kuh) Ziege Unkonjugiert WB   0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
357,50 €
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Human Kaninchen Unkonjugiert EIA, IHC (p), WB   0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
340,48 €
Details
Human Kaninchen Unkonjugiert ELISA, WB Western blot using Rabbit anti-SAE1 antibody shows detection of SAE1. Left lane (-) contains 20 µg human HeLa whole cell protein. Right lane (+) contains 20 µg human HeLa whole cell protein from cells pre-treated with phosphatase inhibitor cocktail to prevent dephosphorylation of the target. Proteins were separated on a 10% SDS-PAGE and transferred onto nitrocellulose. After blocking with 5% milk-TBST 1 hr at room temperature, the membrane was probed with the primary antibody diluted to 2 µg/mL at room temperature for 3 hr followed by washes and reaction with HRP-conjugated secondary and ECL imaging. 25 μL Anmelden zum Anzeigen 5 bis 7 Tage
157,14 €
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SAE1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Human , , ,
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Mouse (Murine)


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Rat (Rattus)


Am meisten referenzierte anti-SAE1 Antikörper

  1. Human Monoclonal SAE1 Primary Antibody für IF, IHC (p) - ABIN564342 : Fujimoto, Matsushita, Hamaguchi, Kaji, Asano, Ogawa, Yamaoka, Fujikawa, Tsukada, Sato, Echigo, Hasegawa, Takehara: Autoantibodies to small ubiquitin-like modifier activating enzymes in Japanese patients with dermatomyositis: comparison with a UK Caucasian cohort. in Annals of the rheumatic diseases 2012 (PubMed)

  2. Human Polyclonal SAE1 Primary Antibody für ELISA, WB - ABIN250021 : Desterro, Rodriguez, Kemp, Hay: Identification of the enzyme required for activation of the small ubiquitin-like protein SUMO-1. in The Journal of biological chemistry 1999 (PubMed)

Weitere Antikörper gegen SAE1 Interaktionspartner

Human SUMO1 Activating Enzyme Subunit 1 (SAE1) Interaktionspartner

  1. Study demonstrate that CdGAP (zeige ARHGAP31 Antikörper) acts as a novel co-transcriptional repressor with Zeb2 (zeige ZEB2 Antikörper) to suppress E-cadherin (zeige CDH1 Antikörper) expression in breast cancer cells.

  2. the expression of SENP8 (zeige SENP8 Antikörper), SAE1, PIAS1 (zeige PIAS1 Antikörper), PIAS2 (zeige PIAS2 Antikörper) and ZMIZ1 (zeige ZMIZ1 Antikörper) is deregulated in the majority of PTC (zeige F9 Antikörper) tissues, likely contributing to the PTC (zeige F9 Antikörper) phenotype.

  3. as it has been shown by flow cytometry analysis, specific knockdown of SAE1 slowed down the cell population at G0/G1 phase and induced apoptosis of RKO cells.

  4. a four-generation pedigree with isolated terminal limb defects and a truncating mutation in ARHGAP31 (zeige ARHGAP31 Antikörper) underscores the relevance of sequencing ARHGAP31 (zeige ARHGAP31 Antikörper) in cases of isolated limb defects, irrespective of presence of a complete Adams-Oliver syndrome phenotype

  5. The focal adhesion-localized CdGAP (zeige ARHGAP31 Antikörper) regulates matrix rigidity sensing and durotaxis.

  6. Data demonstrate that cdGAP (zeige ARHGAP31 Antikörper) negatively regulates directed and random migration by controlling adhesion maturation and dynamics through the regulation of both adhesion assembly and disassembly.

  7. Data indicate the role of anti-SUMO activating enzyme SAE1 and SAE2 (zeige RBBP8 Antikörper) antibody as marker of dermatomyositis.

  8. specific interaction between negatively charged phospholipid PI(3,4,5)P3 and the stretch of polybasic residues preceding the RhoGAP (zeige ARHGAP1 Antikörper) domain regulates CdGAP (zeige ARHGAP31 Antikörper) activity in vivo and is required for its cellular functions.

  9. Data show that the SAE2 (zeige RBBP8 Antikörper) subunit of the small ubiquitin-like modifier (SUMO (zeige SUMO1 Antikörper)) E1 is autoSUMOylated at residue Lys (zeige LYZ Antikörper)-236, and SUMOylation was catalyzed by Ubc9 (zeige UBE2I Antikörper) at several additional Lys (zeige LYZ Antikörper) residues surrounding the catalytic Cys (zeige DNAJC5 Antikörper)-173 of SAE2 (zeige RBBP8 Antikörper).

  10. loss of SAE1/2 activity drives synthetic lethality with Myc (zeige MYC Antikörper); inactivation of SAE2 (zeige RBBP8 Antikörper) leads to mitotic catastrophe and cell death upon Myc (zeige MYC Antikörper) hyperactivation; findings in Myc (zeige MYC Antikörper)-high breast cancers suggest low tumor SAE1 and SAE2 (zeige RBBP8 Antikörper) correlates metastasis-free survival

SAE1 Antigen-Profil

Protein Überblick

Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1\; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 and UBA2 (MIM 613295) form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999

Genbezeichner und Symbole assoziert mit SAE1

  • Rho GTPase activating protein 31 (ARHGAP31) Antikörper
  • SUMO1 activating enzyme subunit 1 (SAE1) Antikörper
  • SUMO1 activating enzyme subunit 1 (Sae1) Antikörper
  • SUMO1 activating enzyme subunit 1 (sae1) Antikörper
  • 2400010M20Rik Antikörper
  • 2610044L12Rik Antikörper
  • AL033372 Antikörper
  • aos Antikörper
  • AOS1 Antikörper
  • Aos1p Antikörper
  • AW743391 Antikörper
  • CDGAP Antikörper
  • D7Ertd177e Antikörper
  • HSPC140 Antikörper
  • Sua1 Antikörper
  • Sua1p Antikörper
  • Uble1a Antikörper

Bezeichner auf Proteinebene für SAE1

Cdc42 GTPase-activating protein , rho GTPase-activating protein 31 , SUMO-1 activating enzyme E1 N subunit , SUMO-1 activating enzyme subunit 1 , SUMO-activating enzyme subunit 1 , activator of SUMO1 , sentrin/SUMO-activating protein AOS1 , ubiquitin-like 1-activating enzyme E1A , ubiquitin-like protein SUMO-1 activating enzyme , ubiquitin-like (sentrin) activating enzyme E1A , ubiquitin-like 1 (sentrin) activating enzyme E1A , ubiquitin-like 1 (sentrin) activating enzyme subunit 1 , SUMO-activating enzyme E1 N subunit

GENE ID SPEZIES
57514 Homo sapiens
10055 Homo sapiens
56459 Mus musculus
308384 Rattus norvegicus
505512 Bos taurus
476425 Canis lupus familiaris
100173973 Pongo abelii
443558 Xenopus laevis
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