anti-SUMO1 Activating Enzyme Subunit 1 (SAE1) Antikörper

Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1\; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. Zusätzlich bieten wir Ihnen SAE1 Proteine (19) und SAE1 Kits (11) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
SAE1 10055 Q9UBE0
SAE1 56459 Q9R1T2
SAE1 308384 Q6AXQ0
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Top anti-SAE1 Antikörper auf antikoerper-online.de

Showing 10 out of 131 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-SAE1 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:1562500<br><b>Positive Control: </b>Hela cell lysate WB Suggested Anti-SAE1 <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500 <br /> Positive Control: Hela cell lysate <br /> SAE1 is supported by BioGPS gene expression data to be expressed in HeLa 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-SAE1 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>Human brain 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert IHC (p), WB The AOS1 C-term Pab (ABIN389081) is used in Western blot to detect AOS1 in mouse heart tissue lysate. Western blot analysis of AOS1 (arrow) using rabbit polyclonal AOS1 Antibody (C-term) (ABIN389081). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the AOS1 gene (Lane 2) (Origene Technologies). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Rind (Kuh) Kaninchen Unkonjugiert EIA, WB 0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
$533.50
Details
Schimpanse Kaninchen Unkonjugiert EIA, IF, IHC (p), WB 0.5 mg Anmelden zum Anzeigen 6 bis 8 Tage
$610.50
Details
Human Ziege Unkonjugiert ELISA, WB ABIN185082 staining (1µg/ml) of Jurkat lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$358.02
Details
Human Maus Unkonjugiert IF, WB Immunofluorescence of monoclonal antibody to SAE1 on HeLa cell (antibody concentration 10 µg/mL). SAE1 monoclonal antibody (M01), clone 1G4-1G5 Western Blot analysis of SAE1 expression in HeLa. 0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
$450.00
Details
Human Kaninchen Unkonjugiert IF, ELISA, WB Western blot analysis of extracts from 293 cells, using AOS1 Antibody. The lane on the right is treated with the synthesized peptide. Immunofluorescence analysis of HuvEc cells, using AOS1 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Rind (Kuh) Ziege Unkonjugiert WB   0.1 mg Anmelden zum Anzeigen 12 bis 15 Tage
$455.40
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB   0.1 mg Anmelden zum Anzeigen 12 bis 15 Tage
$357.50
Details

SAE1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Human , , ,
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Mouse (Murine)


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Rat (Rattus)


Am meisten referenzierte anti-SAE1 Antikörper

  1. Human Monoclonal SAE1 Primary Antibody für IF, IHC (p) - ABIN564342 : Fujimoto, Matsushita, Hamaguchi, Kaji, Asano, Ogawa, Yamaoka, Fujikawa, Tsukada, Sato, Echigo, Hasegawa, Takehara: Autoantibodies to small ubiquitin-like modifier activating enzymes in Japanese patients with dermatomyositis: comparison with a UK Caucasian cohort. in Annals of the rheumatic diseases 2012 (PubMed)

  2. Human Polyclonal SAE1 Primary Antibody für ELISA, WB - ABIN250021 : Desterro, Rodriguez, Kemp, Hay: Identification of the enzyme required for activation of the small ubiquitin-like protein SUMO-1. in The Journal of biological chemistry 1999 (PubMed)

Weitere Antikörper gegen SAE1 Interaktionspartner

Human SUMO1 Activating Enzyme Subunit 1 (SAE1) Interaktionspartner

  1. the expression of SENP8 (zeige SENP8 Antikörper), SAE1, PIAS1 (zeige PIAS1 Antikörper), PIAS2 (zeige PIAS2 Antikörper) and ZMIZ1 (zeige ZMIZ1 Antikörper) is deregulated in the majority of PTC (zeige F9 Antikörper) tissues, likely contributing to the PTC (zeige F9 Antikörper) phenotype.

  2. as it has been shown by flow cytometry analysis, specific knockdown of SAE1 slowed down the cell population at G0/G1 phase and induced apoptosis of RKO cells.

  3. Data indicate the role of anti-SUMO activating enzyme SAE1 and SAE2 (zeige RBBP8 Antikörper) antibody as marker of dermatomyositis.

  4. Data show that the SAE2 (zeige RBBP8 Antikörper) subunit of the small ubiquitin-like modifier (SUMO (zeige SUMO1 Antikörper)) E1 is autoSUMOylated at residue Lys (zeige LYZ Antikörper)-236, and SUMOylation was catalyzed by Ubc9 (zeige UBE2I Antikörper) at several additional Lys (zeige LYZ Antikörper) residues surrounding the catalytic Cys (zeige DNAJC5 Antikörper)-173 of SAE2 (zeige RBBP8 Antikörper).

  5. loss of SAE1/2 activity drives synthetic lethality with Myc (zeige MYC Antikörper); inactivation of SAE2 (zeige RBBP8 Antikörper) leads to mitotic catastrophe and cell death upon Myc (zeige MYC Antikörper) hyperactivation; findings in Myc (zeige MYC Antikörper)-high breast cancers suggest low tumor SAE1 and SAE2 (zeige RBBP8 Antikörper) correlates metastasis-free survival

  6. The mammalian E1 subunits can be imported separately, identify nuclear localization signals (NLSs) in Aos1 and in Uba2, and demonstrate that their import is mediated by importin alpha/beta in vitro and in intact cells.

  7. structures of heterodimeric Sae1/Sae2 (zeige RBBP8 Antikörper)-Mg.ATP and Sae1/Sae2 (zeige RBBP8 Antikörper)-SUMO-1 (zeige SUMO1 Antikörper)-Mg.ATP complexes

  8. SUMO-1 (zeige SUMO1 Antikörper) controls the protein stability and the biological function of phosducin (zeige PDC Antikörper).

Zebrafish SUMO1 Activating Enzyme Subunit 1 (SAE1) Interaktionspartner

  1. sae1 is essential for the maintenance of hematopoietic stem/progenitor cells during fetal hematopoiesis in zebrafish.

SAE1 Antigen-Profil

Protein Überblick

Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1\; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 and UBA2 (MIM 613295) form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999

Genbezeichner und Symbole assoziert mit SAE1

  • SUMO1 activating enzyme subunit 1 (SAE1) Antikörper
  • SUMO1 activating enzyme subunit 1 (Sae1) Antikörper
  • SUMO1 activating enzyme subunit 1 L homeolog (sae1.L) Antikörper
  • SUMO1 activating enzyme subunit 1 (sae1) Antikörper
  • 2400010M20Rik Antikörper
  • 2610044L12Rik Antikörper
  • AL033372 Antikörper
  • aos Antikörper
  • AOS1 Antikörper
  • Aos1p Antikörper
  • AW743391 Antikörper
  • D7Ertd177e Antikörper
  • HSPC140 Antikörper
  • sae2a Antikörper
  • Sua1 Antikörper
  • Sua1p Antikörper
  • uble1a Antikörper
  • wu:fa28b04 Antikörper
  • zgc:86633 Antikörper

Bezeichner auf Proteinebene für SAE1

SUMO-1 activating enzyme E1 N subunit , SUMO-1 activating enzyme subunit 1 , SUMO-activating enzyme subunit 1 , activator of SUMO1 , sentrin/SUMO-activating protein AOS1 , ubiquitin-like 1-activating enzyme E1A , ubiquitin-like protein SUMO-1 activating enzyme , ubiquitin-like (sentrin) activating enzyme E1A , ubiquitin-like 1 (sentrin) activating enzyme E1A , ubiquitin-like 1 (sentrin) activating enzyme subunit 1 , SUMO-activating enzyme E1 N subunit , SUMO1 activating enzyme subunit 2a , Ubiquitin-like 1-activating enzyme E1A , fa28b04

GENE ID SPEZIES
10055 Homo sapiens
56459 Mus musculus
308384 Rattus norvegicus
476425 Canis lupus familiaris
505512 Bos taurus
100173973 Pongo abelii
443558 Xenopus laevis
100718649 Cavia porcellus
415148 Danio rerio
Ausgewählte Anbieter für anti-SAE1 (SAE1) Antikörper
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