anti-RecQ Protein-Like 5 (RECQL5) Antikörper

The protein encoded by RECQL5 is a helicase that is important for genome stability. Zusätzlich bieten wir Ihnen RECQL5 Proteine (3) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
RECQL5 9400 O94762
RECQL5 170472  
RECQL5 287834  
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Top anti-RECQL5 Antikörper auf antikoerper-online.de

Showing 10 out of 67 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Human Kaninchen Unkonjugiert WB RECQL5 Antibody (Center) (ABIN1881739) western blot analysis in human Uterus tissue lysates (35 µg/lane). This demonstrates the RECQL5 antibody detected the RECQL5 protein (arrow). 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: RECQL5 Antibody [NBP1-83438] - Staining of human cell line A-431 shows positivity in nucleus & cytoplasm. Immunohistochemistry-Paraffin: RECQL5 Antibody [NBP1-83438] - Staining of human skeletal muscle shows strong cytoplasmic positivity in myocytes. 0.1 mL Anmelden zum Anzeigen 5 bis 8 Tage
335,00 €
Details
Human Kaninchen Unkonjugiert ELISA, WB 50 μg Anmelden zum Anzeigen 6 bis 8 Tage
459,65 €
Details
Rind (Kuh) Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
653,02 €
Details
Human Kaninchen Unkonjugiert IP, S, WB 100 μL Anmelden zum Anzeigen 2 bis 4 Tage
371,00 €
Details
Human Kaninchen Unkonjugiert IP, WB 0.1 mL Anmelden zum Anzeigen 2 bis 4 Tage
371,00 €
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p) Immunocytochemistry/Immunofluorescence: RECQL5 Antibody [NBP1-83437] - Staining of human cell line A-431 shows positivity in nucleus & nuclear membrane. Immunohistochemistry-Paraffin: RECQL5 Antibody [NBP1-83437] - Staining of human kidney shows strong membranous positivity in cells of tubules. 0.1 mL Anmelden zum Anzeigen 5 bis 8 Tage
335,00 €
Details
Human Kaninchen Unkonjugiert WB RecQL5 antibody used at 0.25 ug/ml to detect target protein. 50 μg Anmelden zum Anzeigen 6 bis 8 Tage
460,89 €
Details
Human Kaninchen Unkonjugiert WB Western blot analysis in human Uterus tissue lysates (35ug/lane). 400 μL Anmelden zum Anzeigen 6 bis 8 Tage
538,22 €
Details

RECQL5 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-RECQL5 Antikörper

  1. Human Polyclonal RECQL5 Primary Antibody für WB - ABIN1881739 : Schwendener, Raynard, Paliwal, Cheng, Kanagaraj, Shevelev, Stark, Sung, Janscak: Physical interaction of RECQ5 helicase with RAD51 facilitates its anti-recombinase activity. in The Journal of biological chemistry 2010 (PubMed)
    Zeige alle 5 Referenzen für 1881739

  2. Human Polyclonal RECQL5 Primary Antibody für ICC, IF - ABIN4349789 : Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. in Nature methods 2013 (PubMed)
    Zeige alle 2 Referenzen für 4349789

  3. Cow (Bovine) Polyclonal RECQL5 Primary Antibody für WB - ABIN2775189 : Garcia, Liu, Jiricny, West, Janscak: Human RECQ5beta, a protein with DNA helicase and strand-annealing activities in a single polypeptide. in The EMBO journal 2004 (PubMed)

Weitere Antikörper gegen RECQL5 Interaktionspartner

Human RecQ Protein-Like 5 (RECQL5) Interaktionspartner

  1. RECQ5 removes RAD51 (zeige RAD51 Antikörper) filaments stabilizing stalled replication forks at common fragile sites and hence facilitates CFS cleavage by MUS81 (zeige MUS81 Antikörper)-EME1 (zeige EME1 Antikörper).

  2. the open and closed forms of RECQL5 were used together with a quantitative comparison of all current RecQ family structures to construct a mechanistic model for RECQL5 helicase activity

  3. Study characterized the G-quadruplex (GQ) unfolding activity of RECQ5 for different DNA constructs under different salt conditions, showed that RECQ5 is overall a weak GQ destabilizer compared to Bloom and Werner

  4. interaction between RECQ5 and proliferating cell nuclear antigen (PCNA (zeige PCNA Antikörper)) promotes RAD18 (zeige RAD18 Antikörper)-dependent PCNA (zeige PCNA Antikörper) ubiquitination and the helicase activity of RECQ5 promotes the processing of replication intermediates.

  5. RECQL5 has unique strand annealing properties relative to the other human RecQ helicase proteins

  6. RECQL5 is a critical regulator of genome stability in myeloproliferative neoplasms and demonstrate that replication stress-associated cytotoxicity can be amplified specifically in JAK2V617F mutant cells through RECQL5-targeted synthetic lethality.

  7. Expression of RECQL5 in breast cancer can drive proliferation supporting an oncogenic function for RECQL5 in breast cancer. RECQL5 is a promising biomarker in breast cancer.

  8. RecQ5 prevents transcription associated genome instability by facilitating PIAS1 (zeige PIAS1 Antikörper)-SRSF1 (zeige SRSF1 Antikörper) ligase complex sumoylation of DNA topoisomerase 1 (zeige TOP1 Antikörper).

  9. results suggested RECQL5 as a tumor suppressor in osteosarcoma and may be a potential therapeutic target for osteosarcoma treatment

  10. PARylation is involved in the recruitment of RECQL5 and WRN to laser-induced DNA damage and RECQL5 and WRN have differential responses to PARylated PARP1 and Poly(ADP-ribose).

Mouse (Murine) RecQ Protein-Like 5 (RECQL5) Interaktionspartner

  1. Recql5 protects the liver against LPS (zeige TLR4 Antikörper)/D-Gal (zeige GAL Antikörper)-induced injury by suppressing hepatocyte apoptosis and oxidative stress and modulation of CYP450 expression.

  2. Recql5 has a tumor suppressor role in the gastrointestinal tract of Apc (zeige APC Antikörper)(min) mice.

  3. Recql5-deficient cells exhibit elevated frequencies of spontaneous DNA double-strand breaks and homologous recombination (

  4. Data suggest that Recql5 helps maintain active DNA replication to prevent collapse of replication forks and accumulation of DSBs, preserve genome integrity and prevent cell death after replication stress due to topoisomerase I (zeige TOP1 Antikörper) poisoning.

RECQL5 Antigen-Profil

Protein Überblick

The protein encoded by this gene is a helicase that is important for genome stability. The encoded protein also prevents aberrant homologous recombination by displacing RAD51 from ssDNA. Three transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit RECQL5

  • RecQ protein-like 5 (RECQL5) Antikörper
  • RecQ protein-like 5 (recql5) Antikörper
  • RecQ protein-like 5 (LOC100225598) Antikörper
  • RecQ protein-like 5 (Recql5) Antikörper
  • DKFZp459N0627 Antikörper
  • RECQ5 Antikörper
  • Recq5b Antikörper
  • Recql5b Antikörper

Bezeichner auf Proteinebene für RECQL5

ATP-dependent DNA helicase Q5 , RecQ protein-like 5 , ATP-dependent DNA helicase Q5-like , DNA helicase, RecQ-like type 5

GENE ID SPEZIES
373891 Gallus gallus
454885 Pan troglodytes
566553 Danio rerio
702951 Macaca mulatta
100027279 Monodelphis domestica
100059566 Equus caballus
100173649 Pongo abelii
100216093 Xenopus (Silurana) tropicalis
100225598 Taeniopygia guttata
100397260 Callithrix jacchus
100469169 Ailuropoda melanoleuca
100544199 Meleagris gallopavo
9400 Homo sapiens
512590 Bos taurus
170472 Mus musculus
287834 Rattus norvegicus
483317 Canis lupus familiaris
100626380 Sus scrofa
Ausgewählte Anbieter für anti-RECQL5 (RECQL5) Antikörper
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