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RalA Binding Protein 1 Proteine (RALBP1)

Can activate specifically hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. Zusätzlich bieten wir Ihnen RALBP1 Antikörper (115) und RALBP1 Kits (7) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
RALBP1 19765 Q62172
RALBP1 84014 Q62796
RALBP1 10928 Q15311
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Showing 10 out of 14 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 56 Days
7.380,00 €
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Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 56 Days
7.380,00 €
Details
HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
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HOST_Escherichia coli (E. coli) Human His tag   100 μg Anmelden zum Anzeigen 13 bis 17 Tage
740,95 €
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HOST_Escherichia coli (E. coli) Maus His tag   100 μg Anmelden zum Anzeigen 13 bis 17 Tage
761,90 €
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HOST_Escherichia coli (E. coli) Ratte His tag   100 μg Anmelden zum Anzeigen 13 bis 17 Tage
777,14 €
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HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 6 bis 8 Tage
748,00 €
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HOST_Escherichia coli (E. coli) Human Unkonjugiert   100 μg Anmelden zum Anzeigen 7 bis 14 Tage
923,21 €
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HOST_Escherichia coli (E. coli) Maus Unkonjugiert   100 μg Anmelden zum Anzeigen 7 bis 14 Tage
949,40 €
Details
HOST_Escherichia coli (E. coli) Ratte Unkonjugiert   100 μg Anmelden zum Anzeigen 7 bis 14 Tage
962,50 €
Details

RALBP1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Mouse (Murine) ,

Rat (Rattus)

Human , , ,
, ,

Weitere Proteine zu RalA Binding Protein 1 (RALBP1) Interaktionspartnern

Xenopus laevis RalA Binding Protein 1 (RALBP1) Interaktionspartner

  1. Affects dynamics of the actin cytoskeleton, signalling from Ral (zeige rala Proteine) to RLIP is required for gastrulation.

  2. These results demonstrate that to participate in the control of the actin cytoskeleton, RLIP needs its complete N-terminal region coding for the mu2BD and the GAP domain.

Mouse (Murine) RalA Binding Protein 1 (RALBP1) Interaktionspartner

  1. RLIP76 acts as a scaffold at recycling endosomes by binding activated R-Ras, recruiting ARNO (zeige CYTH2 Proteine) to activate Arf6 (zeige ARF6 Proteine), thereby contributing to cell spreading and migration.

  2. a fundamental role of RLIP76 in regulating the function of obesity-promoting pro-inflammatory cytokines

  3. RalBP1 is a gene regulating the seizure threshold and synaptic inhibition in mice

  4. results establish that RLIP76 is required for efficient endothelial cell function and angiogenesis in solid tumors

  5. RLIP76 represents a mechanistically significant target for developing effective interventions in aggressive and refractory pancreatic cancers

  6. Studies confirmed a model in which RLIP76 plays a central role in the pathogenesis of metabolic syndrome and RLIP76 loss causes profound and global alterations of MSy signaling functions.

  7. Findings show a fundamental role of RLIP76 in chemical carcinogenesis.

  8. Because RLIP76 is induced by oxidative stress, it could play a role in insulin (zeige INS Proteine) resistance seen in pathological conditions characterized by increased oxidative stress

  9. Data show that RLIP76 knockout mice are extremely sensitive to irradiation.

  10. role in regulating endocytosis of activin type II receptors by ARIP2 (zeige SYNJ2BP Proteine)

Human RalA Binding Protein 1 (RALBP1) Interaktionspartner

  1. the miR143-3p level was markedly lower in participants with ovarian cancer compared with normal control, while the expression of RALBP1 mRNA and protein were evidently overexpressed in participants with ovarian cancer compared with normal control.

  2. RLIP76 knockdown increased autophagic flux and apoptosis in U251 glioma cells.

  3. Phosphorylation level of Akt (zeige AKT1 Proteine) declined from 138.45+/-13.8 to 69.9+/-29.7% in SGC (zeige SGCB Proteine)-7901, and from 115.5+/-26.6 to 49.07+/-27% in MGC-803 and phosphorylation level of mTOR (zeige FRAP1 Proteine) also significantly decreased.While apoptosis of gastric cancer(GA) cells increased which we verified with apoptosis proteins and staining analysis. Our data showed that RLIP76 plays a significant oncogenic role in GC and it maybe a potential target in GC

  4. Anti-tumor effect was exerted when miR (zeige MLXIP Proteine)-124 directly targeted RLIP76, a stress-inducible transporter that plays a crucial role in the development of melanoma.

  5. report showed that RLIP76 expression was significantly increased in breast cancer samples and positively correlated with the malignant status of breast cancer patients; results indicated that high RLIP76 expression was associated with poor prognosis of breast cancer patients

  6. RLIP76 expression is induced by TNF-alpha (zeige TNF Proteine) and follows the induction kinetics of inflammation markers, suggesting that inflammation can influence RLIP76 expression at the blood brain barrier.

  7. RLIP76 downregulation in HT29 CRC (zeige CALR Proteine) cells suppressed cell growth, enhanced cell apoptosis, induced cell cycle arrest, and inhibited cell invasion by decreasing MMP2 (zeige MMP2 Proteine) expression.

  8. High RLIP76 expression is associated with a poor outcome of meningioma.

  9. results revealed that the effect of miR (zeige MLXIP Proteine)-101 on prostate cancer cell apoptosis was due to RLIP76 regulation of the PI3K (zeige PIK3CA Proteine)/Akt (zeige AKT1 Proteine)/Bcl-2 (zeige BCL2 Proteine) signaling pathway

  10. RalBP1 protein is an independent predictor of poor survival and early relapse for CRC (zeige CALR Proteine) patients

RALBP1 Protein Überblick

Protein Überblick

Can activate specifically hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. Mediates ATP-dependent transport of S-(2,4-dinitrophenyl)-glutathione (DNP-SG) and doxorubicin (DOX) and is the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes. Can catalyze transport of glutathione conjugates and xenobiotics, and may contribute to the multidrug resistance phenomenon. Serves as a scaffold protein that brings together proteins forming an endocytotic complex during interphase and also with CDK1 to switch off endocytosis, One of its substrates would be EPN1/Epsin (By similarity).

Genbezeichner und Symbole assoziert mit RALBP1

  • ralA binding protein 1 (ralbp1)
  • ralA binding protein 1 (RALBP1)
  • ralA binding protein 1 (Ralbp1)
  • RALBP1 Protein
  • RIP1 Protein
  • rlip-A Protein
  • RLIP1 Protein
  • RLIP76 Protein

Bezeichner auf Proteinebene für RALBP1

ralA binding protein 1 , Ral interacting protein , ralA-binding protein 1 , ralA-binding protein 1-like , DNP-SG ATPase , Ral-interacting protein 1 , dinitrophenyl S-glutathione ATPase , cytocentrin , ral-interacting protein 1 , 76 kDa Ral-interacting protein

GENE ID SPEZIES
394288 Xenopus laevis
429466 Gallus gallus
455292 Pan troglodytes
523324 Bos taurus
100379815 Xenopus (Silurana) tropicalis
100431225 Pongo abelii
100478485 Ailuropoda melanoleuca
100519155 Sus scrofa
100549203 Meleagris gallopavo
100557384 Anolis carolinensis
100600679 Nomascus leucogenys
19765 Mus musculus
84014 Rattus norvegicus
10928 Homo sapiens
490548 Canis lupus familiaris
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