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RAN Binding Protein 1 Proteine (RANBP1)

Ran/TC4-binding protein, RanBP1, interacts specifically with GTP-charged RAN. Zusätzlich bieten wir Ihnen RANBP1 Antikörper (68) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
RANBP1 5902 P43487
RANBP1 19385 P34022
Ratte RANBP1 RANBP1 360739  
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Showing 9 out of 9 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Anmelden zum Anzeigen 11 bis 15 Tage
303,81 €
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 26 bis 31 Tage
4.115,41 €
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HOST_Escherichia coli (E. coli) Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 26 bis 31 Tage
4.115,41 €
Details
HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
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Hefe Rind (Kuh) His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.381,59 €
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HOST_Escherichia coli (E. coli) Human His tag Validation with Western Blot 50 μg Anmelden zum Anzeigen 6 bis 8 Tage
218,90 €
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HOST_Insect cells (Sf9) Human His tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 16 Days
438,90 €
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HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 6 bis 8 Tage
748,00 €
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HOST_Escherichia coli (E. coli) Human Unkonjugiert   100 μg Anmelden zum Anzeigen 6 bis 8 Tage
374,15 €
Details

RANBP1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , ,
, ,
Mouse (Murine)

Am meisten referenzierte RANBP1 Proteine

  1. Human RANBP1 Protein expressed in Escherichia coli (E. coli) - ABIN1098236 : Hayashi, Yokoyama, Seki, Azuma, Ohba, Nishimoto: RanBP1, a Ras-like nuclear G protein binding to Ran/TC4, inhibits RCC1 via Ran/TC4. in Molecular & general genetics : MGG 1995 (PubMed)

Weitere Proteine zu RAN Binding Protein 1 (RANBP1) Interaktionspartnern

Xenopus laevis RAN Binding Protein 1 (RANBP1) Interaktionspartner

  1. findings reveal an important mitotic role for RanBP1, controlling the spatial distribution and magnitude of mitotic Ran-GTP (zeige AK3 Proteine) production and thereby ensuring accurate execution of Ran-dependent mitotic events

Human RAN Binding Protein 1 (RANBP1) Interaktionspartner

  1. Sgk1 (zeige SGK1 Proteine)-dependent regulation of RANBP1 has functional consequences on both mitotic microtubule activity and taxol sensitivity of cancer cells.

  2. in vitro and in vivo phosphorylation of RanBP1 by Plk1 as well as the importance of phosphorylation of RanBP1 in the interaction between Plk1 and Ran during early mitosis, is demonstrated.

  3. RANBP1 on 22q11.21 locus might be causally related to the smooth pursuit eye movement abnormality rather than the development of schizophrenia.

  4. Downregulation of the Ran GTPase (zeige RAN Proteine) effector RanBP1 is required for nuclear reorganisation.

  5. structure of the Ran-RanBP1-RanGAP complex

  6. Phosphorylated wild type RanGAP1 (zeige RANGAP1 Proteine), but not a mutant harboring a mutation at the phosphorylation site 358S, efficiently formed a stable ternary complex with Ran and RanBP1 in vivo, suggesting that the 358S phosphorylation of RanGAP1 (zeige RANGAP1 Proteine) affects the Ran system.

  7. These data indicate that RANBP1 activity is required for the proper localization of specific factors that regulate microtubule function; loss of this activity contributes to the generation of aneuploidy in a microtubule-dependent manner.

  8. RanBP1-interfered cells show an increased apoptotic response to taxol compared to their counterpart with normal or high RanBP1 levels, and this response is caspase-3 (zeige CASP3 Proteine) dependent.

  9. Generation of Ran-GTP (zeige AK3 Proteine) from Ran-GDP by importin-beta (zeige KPNB1 Proteine) is activated by Ran-binding protein-1 (RanBP1) that forms a trimeric complex with Ran-GDP and importin-beta (zeige KPNB1 Proteine).

Mouse (Murine) RAN Binding Protein 1 (RANBP1) Interaktionspartner

  1. Ranbp1 emerges as a microcephaly gene within the 22q11.2 deleted region that may contribute to altered cortical precursor proliferation and neurogenesis associated with broader 22q11.2 deletion.

  2. Data suggest Ran activation by RanBP1 in macrophages promotes Legionella phagosome formation and phagocytosis; LegG1 functions as bacterial Ran activator, localizes to phagosomes, and promotes microtubule stabilization, phagocytosis, and replication.

  3. The dramatic decrease in "RanBP" activity impairs germ cell viability and affects spermatogenesis decisively in RanBP1-knockout mice.

  4. Downregulation of the Ran GTPase (zeige RAN Proteine) effector RanBP1 is required for nuclear reorganisation.

  5. expressed in the frontonasal processes, branchial arches, aortic arches, and limb buds. At these sites, RanBP1 apparently coincides with neural crest-derived mesenchymal cells. In addition, RanBP1 is expressed in the forebrain

  6. RanBP1 interferes with crucial factor(s) that control structural and dynamic features of centrosomes during mitosis

  7. Tax (zeige CNTN2 Proteine) directly binds Ran and Ran-binding protein-1, locates to centrosomes/spindle poles, and causes supernumerary centrosomes

RANBP1 Protein Überblick

Protein Überblick

Ran/TC4-binding protein, RanBP1, interacts specifically with GTP-charged RAN. RANBP1 encodes a 23-kD protein that binds to RAN complexed with GTP but not GDP. RANBP1 does not activate GTPase activity of RAN but does markedly increase GTP hydrolysis by the RanGTPase-activating protein (RanGAP1). The RANBP1 cDNA encodes a 201-amino acid protein that is 92% similar to its mouse homolog. In both mammalian cells and in yeast, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN.

Genbezeichner und Symbole assoziert mit RAN Binding Protein 1 Proteine (RANBP1)

  • RAN binding protein 1 (ranbp1)
  • Ran binding protein 1 (LOC397932)
  • ran binding protein 1 (PVX_090070)
  • RAN binding protein 1 (GL50803_16969)
  • RAN binding protein 1 (LOC100343953)
  • RAN binding protein 1 (RANBP1)
  • RAN binding protein 1 (Ranbp1)
  • hm:zeh1094 Protein
  • Htf9a Protein
  • MGC64314 Protein
  • wu:fa96a09 Protein
  • wu:fj39g07 Protein
  • zeh1094 Protein
  • zgc:85649 Protein

Bezeichner auf Proteinebene für RAN Binding Protein 1 Proteine (RANBP1)

RAN binding protein 1 , Ran binding protein 1 , ran binding protein 1 , ran-specific GTPase-activating protein , HpaII tiny fragments locus 9A , Htf9-a/RanBP1 , hpaII tiny fragments locus 9a protein , ran-binding protein 1

GENE ID SPEZIES
379454 Xenopus laevis
397932 Xenopus laevis
5474397 Plasmodium vivax Sal-1
5701654 Giardia lamblia ATCC 50803
100343953 Oryctolagus cuniculus
337046 Danio rerio
5902 Homo sapiens
19385 Mus musculus
360739 Rattus norvegicus
533251 Bos taurus
416787 Gallus gallus
477563 Canis lupus familiaris
100151896 Sus scrofa
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