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RAB proteins, such as RAB25, are members of the RAS superfamily of small GTPases that are involved in membrane trafficking. Zusätzlich bieten wir Ihnen RAB25 Proteine (8) und viele weitere Produktgruppen zu diesem Protein an.
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Human Monoclonal RAB25 Primary Antibody für IHC (fro), IHC (p) - ABIN449921
Davidson, Holth, Hellesylt, Tan, Huang, Tropé, Nesland, Thiery: The clinical role of epithelial-mesenchymal transition and stem cell markers in advanced-stage ovarian serous carcinoma effusions. in Human pathology 2014
Human Monoclonal RAB25 Primary Antibody für IHC, ELISA - ABIN966930
Goldenring, Shen, Vaughan, Modlin: Identification of a small GTP-binding protein, Rab25, expressed in the gastrointestinal mucosa, kidney, and lung. in The Journal of biological chemistry 1993
Human Monoclonal RAB25 Primary Antibody für IHC, ELISA - ABIN969489
Wang, Kumar, Navarre, Casanova, Goldenring: Regulation of vesicle trafficking in madin-darby canine kidney cells by Rab11a and Rab25. in The Journal of biological chemistry 2000
Show all 2 Pubmed References
The results from this analysis indicated that Rab11a (zeige RAB11A Antikörper), Rab11c(Rab25) and Rab14 (zeige RAB14 Antikörper) were expressed in a wide range of cell lines, including the human placental trophoblastic BeWo cell line.
Data show that Rab25 is responsible for RIN1 (zeige RIN1 Antikörper)-induced EGFR (zeige EGFR Antikörper) signaling and tumor malignancy in clear cell renal cell carcinoma (zeige MOK Antikörper) cell.
Promoter methylation results in downregulation of RAB25 expression in oropharyngeal squamous cell carcinoma. Decreased Rsb25 expression is associated with lymph node metastasis.
Rab25 may act as a tumor promoter.
Rab25 was upregulated in hepatocellular carcinoma tissues and cells compared with normal liver tissues and cell lines. Rab25 overexpression correlated with advanced tumor stage and nodal metastasis.Rab25 depletion blocked cell growth rate, inhibited colony formation, downregulated AKT (zeige AKT1 Antikörper) phosphorylation, inhibited the Wnt (zeige WNT2 Antikörper) signaling pathway and its target genes, and negatively regulated the invading ability of HCC (zeige FAM126A Antikörper) cells.
Data show that both rab (zeige HRB Antikörper) G-Protein RAB25 and RNA-binding protein (zeige PTBP1 Antikörper) ESRP1 (zeige ESRP1 Antikörper) were suppressed by transcription factor ZEB1 (zeige ZEB1 Antikörper), which was in turn regulated via epigenetic mechanisms.
Rab25 expression is a potential prognostic index for advanced NSCLC patients and its inhibition may improve chemosensitization in NSCLC treatment.
These results showed that high levels of Rab25 expression were significantly correlated with renal cell carcinoma (zeige MOK Antikörper) invasion classification (P < 0.01), lymph-node metastasis (P < 0.001), and pathological stage (P < 0.01).
High RAB25 expression is associated with good clinical outcome in patients with locally advanced head and neck squamous cell carcinoma.
the crystal structure of Rab25 in complex with the C-terminal region of FIP2 (zeige OPTN Antikörper), which consists of a central dimeric FIP2 (zeige OPTN Antikörper) coiled-coil that mediates a heterotetrameric Rab25-(FIP2 (zeige OPTN Antikörper))2-Rab25 complex.
a Grhl2 (zeige GRHL2 Antikörper)/Ovol2 (zeige OVOL2 Antikörper) network controls Cldn4 (zeige CLDN4 Antikörper) and Rab25 expression that facilitates lumen expansion and barrier formation in subtypes of renal epithelia
tight regulation of CCN3 (zeige NOV Antikörper) expression is necessary for normal cortical neuronal connectivity during development, and RAB25 negatively regulates neuronal differentiation as a downstream effector of CCN3 (zeige NOV Antikörper)
the results indicate that Grhl2 (zeige GRHL2 Antikörper) regulates epithelial morphogenesis through transcriptional up-regulation of Cldn3 (zeige CLDN3 Antikörper) and Cldn4 (zeige CLDN4 Antikörper), as well as of Rab25, which increases the Cldn4 (zeige CLDN4 Antikörper) protein and its localization at TJs
Rab25 may function as a tumor suppressor in intestinal epithelial cells through regulation of protein trafficking to the cell surface.
RAB proteins, such as RAB25, are members of the RAS superfamily of small GTPases that are involved in membrane trafficking. Members of the RAB11 subfamily, including RAB25, control the return of internalized membrane-associated moieties to the cell surface (Caswell et al., 2007
RAB25, member RAS oncogene family
, ras-related protein Rab-25
, Ras-related protein Rab-25
, small GTP-binding protein