anti-Protein Kinase D3 (PRKD3) Antikörper

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. Zusätzlich bieten wir Ihnen Protein Kinase D3 Proteine (11) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
PRKD3 23683 O94806
PRKD3 75292 Q8K1Y2
PRKD3 313834  
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Top anti-Protein Kinase D3 Antikörper auf antikoerper-online.de

Showing 10 out of 117 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert IHC (p), WB Western blot analysis of anti-PKCnu C-term Pab (ABIN391015) in NCI-H460 cell lysate. PKCnu (arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence. Upper panel, western blot analysis of GFP fusion protein expression in Panc-1 cells by using an anti-GFP antibody. Lanes 1 and 5: non-transfected cells. lanes 2 and 6: GFP-PKD-transfected cells. lanes 3 and 7: GFP-PKD2-transfected cells. lanes 4 and 8: GFP-PKD3 transfected cells. Center panel, western blot analysis of GFP fusion protein expression in Panc-1 cells by using PKD3 N-term (ABIN391014) and C-term (ABIN391015) antibodies. Lower panel, indirect immunofluorescence analysis of GFP-PKD3 fusion protein expression in Panc-1 cells by using ABIN391014 and ABIN391015 antibodies. Data courtesy of Dr. Osvaldo Rey, University of California Los Angeles. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert IHC (p), WB Western blot analysis of Prkd3 (arrow) using rabbit polyclonal Mouse Prkd3 Antibody (N-term) (ABIN658062). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the Prkd3 gene. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert IP, WB Detection of Human PKD3 by Western Blot. Sample: Whole cell lysate (30 mcg) from HEK293 cells. Antibody: Affinity purified rabbit anti-PKD3 antibody ABIN250697 used at 1 mcg/ml. Detection: Chemiluminescence with an exposure time of 1 minute. Western Blot: Protein Kinase D3 Antibody [ABIN250697] - Samples: Whole cell lysate from HeLa (5, 15 and 50 ug for WB; 1 mg for IP, 20% of IP loaded) and mouse NIH3T3 (M; 50 ug) cells. Antibodies: Affinity purified rabbit anti-PKD3 antibody used for WB at 0.4 ug/ml (A) and 1 ug/ml (B) and used for IP at 3 ug/mg lysate. Detection: Chemiluminescence with exposure times of 3 minutes (A and B). 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$556.31
Details
Human Kaninchen Unkonjugiert IHC (p), WB Western blot analysis of anti-PKCnu Pab (ABIN391014) in lysate of HL60 cells stimulated with PMA (lane A) and mouse brain tissue lysate (lane B). PKCnu (arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence. Upper panel, western blot analysis of GFP fusion protein expression in Panc-1 cells by using an anti-GFP antibody. Lanes 1 and 5: non-transfected cells. lanes 2 and 6: GFP-PKD-transfected cells. lanes 3 and 7: GFP-PKD2-transfected cells. lanes 4 and 8: GFP-PKD3 transfected cells. Center panel, western blot analysis of GFP fusion protein expression in Panc-1 cells by using PKD3 N-term (ABIN391014) and C-term (ABIN391015) antibodies. Lower panel, indirect immunofluorescence analysis of GFP-PKD3 fusion protein expression in Panc-1 cells by using ABIN391014 and ABIN391015 antibodies. Data courtesy of Dr. Osvaldo Rey, University of California Los Angeles. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert IF, IHC (p), WB   0.4 mL Anmelden zum Anzeigen 12 bis 15 Tage
$518.65
Details
Human Kaninchen Unkonjugiert IF, IHC (p), WB   0.4 mL Anmelden zum Anzeigen 12 bis 15 Tage
$518.65
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human colon carcinoma labeled with Anti-PRKD3 Polyclonal Antibody, Unconjugated (ABIN754678) at 1:200 followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded rat kidney tissue labeled with Anti-PRKD3 Polyclonal Antibody, Unconjugated (ABIN754678) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
$306.90
Details
Human Maus Unkonjugiert ELISA, WB Detection limit for recombinant GST tagged PRKD3 is approximately 1ng/ml as a capture antibody. Western Blot detection against Immunogen (36.63 KDa) . 100 μg Anmelden zum Anzeigen 11 bis 12 Tage
$440.00
Details
Human Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$463.83
Details
Human Kaninchen Cy3 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$405.90
Details

PRKD3 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-Protein Kinase D3 Antikörper

  1. Human Polyclonal PRKD3 Primary Antibody für IP, WB - ABIN250697 : Watkins, Lewandowski, Meek, Storz, Toker, Piwnica-Worms: Phosphorylation of the Par-1 polarity kinase by protein kinase D regulates 14-3-3 binding and membrane association. in Proceedings of the National Academy of Sciences of the United States of America 2008 (PubMed)
    Show all 6 Pubmed References

  2. Human Polyclonal PRKD3 Primary Antibody für IHC (p), WB - ABIN391014 : Yeaman, Ayala, Wright, Bard, Bossard, Ang, Maeda, Seufferlein, Mellman, Nelson, Malhotra: Protein kinase D regulates basolateral membrane protein exit from trans-Golgi network. in Nature cell biology 2004 (PubMed)
    Show all 4 Pubmed References

  3. Human Monoclonal PRKD3 Primary Antibody für ELISA, WB - ABIN565151 : Borges, Döppler, Perez, Andorfer, Sun, Anastasiadis, Thompson, Geiger, Storz: Pharmacologic reversion of epigenetic silencing of the PRKD1 promoter blocks breast tumor cell invasion and metastasis. in Breast cancer research : BCR 2014 (PubMed)

Weitere Antikörper gegen Protein Kinase D3 Interaktionspartner

Human Protein Kinase D3 (PRKD3) Interaktionspartner

  1. None of the Polymorphous low-grade adenocarcinoma (PLGA) lacking PRKD1 (zeige PRKD1 Antikörper) somatic mutations or PRKD gene family rearrangements harboured somatic mutations in the kinase domains of the PRKD2 (zeige PKD2 Antikörper) or PRKD3 genes.

  2. This study discovered and characterized a novel, highly conserved N-terminal domain, comprising 92 amino acids, which mediates dimerization of Protein Kinase D (PKD) isoforms, PKD1 (zeige PKD1 Antikörper), PKD2 (zeige PKD2 Antikörper), and PKD3 monomers.

  3. Studies indicate that the loss of protein kinase D PKD1 is thought to promote invasion and metastasis, while PKD2 (zeige PKD2 Antikörper) and upregulated PKD3 to be positive regulators of proliferation.

  4. Loss of PKD2 (zeige PKD2 Antikörper) enhanced KC proliferative potential while loss of PKD3 resulted in a progressive proliferation defect, loss of clonogenicity and diminished tissue regenerative ability.

  5. for the first time, PKD3 is implicated in the transcription activation of latent HIV-1 provirus, and our results revealed a molecular mechanism of prostratin-induced HIV-1 transcription via PKCepsilon (zeige PRKCE Antikörper)/PKD3/NF-kappaB (zeige NFKB1 Antikörper) signaling pathway.

  6. Activation of PKD2 (zeige PKD2 Antikörper) and further increase of PKD3 activity leads to additional phosphorylation and inhibition of endogenous phosphatase slingshot 1L (zeige SSH1 Antikörper).

  7. PKD3 in TNBC cells provides a molecular connection between the Golgi and endolysosomal compartments to enhance proliferative mTORC1-S6K1 (zeige RPS6KB1 Antikörper) signaling.

  8. PKD3 negatively regulates human airway epithelial barrier formation and integrity through down-regulation of claudin-1 (zeige CLDN7 Antikörper), which is a key component of tight junctions.

  9. PKD3 may contribute to the malignant progression of prostate cancer cells through negative regulation of MMP-7 (zeige MMP7 Antikörper) expression.

  10. PKD3 contributes to the proliferation and malignant growth of androgen-dependent prostate cancer cells in part by upregulating PSA expression.

Mouse (Murine) Protein Kinase D3 (PRKD3) Interaktionspartner

  1. These data provide new insights of a specific PKD3 signaling pathway by identifying a new function, which has not been identified before.

  2. Erythropoietin (zeige EPO Antikörper) regulates GATA1 (zeige GATA1 Antikörper) through protein kinase D (zeige PRKD1 Antikörper) activation, promoting histone deacetylase 5 (zeige HDAC5 Antikörper) dissociation from GATA1 (zeige GATA1 Antikörper), and subsequent GATA1 (zeige GATA1 Antikörper) acetylation.

  3. These data validate PKD3 as a promising therapeutic target in prostate cancer and shed light on the role of secreted tumor-promoting factors in prostate cancer progression.

  4. PKCnu is an important component of signaling pathways downstream from novel PKC enzymes after B-cell receptor engagement

  5. the catalytic activity of PKD3 may regulate its nuclear import through autophosphorylation and/or interaction with another protein

  6. PKD3 is increasingly expressed in neuronal as well as in the supporting connective tissue and in skeletal muscles

  7. reveal a novel distinction between the exocrine and endocrine cells of the pancreas and further identify PKD3 as a signaling molecule that promotes hormone-stimulated amylase (zeige AMY Antikörper) secretion

Protein Kinase D3 (PRKD3) Antigen-Profil

Protein Überblick

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. This kinase can be activated rapidly by the agonists of G protein-coupled receptors. It resides in both cytoplasm and nucleus, and its nuclear accumulation is found to be dramatically enhanced in response to its activation. This kinase can also be activated after B-cell antigen receptor (BCR) engagement, which requires intact phopholipase C gamma and the involvement of other PKC family members.

Genbezeichner und Symbole assoziert mit PRKD3

  • protein kinase D3 (PRKD3) Antikörper
  • protein kinase D3 (prkd3) Antikörper
  • protein kinase D3 (Prkd3) Antikörper
  • 4930557O20Rik Antikörper
  • 5730497N19Rik Antikörper
  • EPK2 Antikörper
  • nPKC-NU Antikörper
  • PKC-NU Antikörper
  • Pkcnu Antikörper
  • PKD3 Antikörper
  • Prkcn Antikörper
  • PRKD3 Antikörper

Bezeichner auf Proteinebene für PRKD3

protein kinase C nu type , protein kinase C, nu , protein kinase EPK2 , protein-serine/threonine kinase , serine/threonine-protein kinase D3 , protein kinase D3 , serine/threonine-protein kinase D3-like , nPKC-nu

GENE ID SPEZIES
23683 Homo sapiens
421478 Gallus gallus
459158 Pan troglodytes
483036 Canis lupus familiaris
538447 Bos taurus
709647 Macaca mulatta
100397078 Callithrix jacchus
100438207 Pongo abelii
100466224 Ailuropoda melanoleuca
100523181 Sus scrofa
100077901 Ornithorhynchus anatinus
100563064 Anolis carolinensis
100581692 Nomascus leucogenys
75292 Mus musculus
313834 Rattus norvegicus
100712662 Cavia porcellus
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