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Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9) ELISA Kits

PCSK9 encodes a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. Zusätzlich bieten wir Ihnen PCSK9 Antikörper (152) und PCSK9 Proteine (61) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
PCSK9 255738 Q8NBP7
PCSK9 100102 Q80W65
PCSK9 298296 P59996
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Top PCSK9 ELISA Kits auf antikoerper-online.de

Showing 10 out of 66 products:

Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human 0.11 ng/mL 0.45-30 ng/mL Typical standard curve 96 Tests Anmelden zum Anzeigen 9 bis 12 Tage
772,39 €
Details
Maus 10pg/mL 62.5-4000 pg/mL Mouse PCSK9 PicoKine ELISA Kit standard curve 96 Tests Anmelden zum Anzeigen 8 bis 11 Tage
507,05 €
Details
Affe 1.1 pg/mL 1.1-800 pg/mL Typical standard curve 96 Tests Anmelden zum Anzeigen 9 bis 12 Tage
874,71 €
Details
Ratte 1.19 ng/mL 3.12-200 ng/mL 96 Tests Anmelden zum Anzeigen 7 bis 10 Tage
804,23 €
Details
Huhn 4.688 ng/mL 7.813-500 ng/mL   96 Tests Anmelden zum Anzeigen 6 bis 8 Tage
666,67 €
Details
Kaninchen 0.188 ng/mL 0.313-20 ng/mL   96 Tests Anmelden zum Anzeigen 6 bis 8 Tage
666,67 €
Details
Schwein 0.469 ng/mL 0.781-50 ng/mL   96 Tests Anmelden zum Anzeigen 6 bis 8 Tage
666,67 €
Details
Meerschweinchen 0.094 ng/mL 0.156-10 ng/mL   96 Tests Anmelden zum Anzeigen 6 bis 8 Tage
666,67 €
Details
Maus 94-6000 pg/mL   1 kit Anmelden zum Anzeigen 8 bis 9 Tage
768,00 €
Details
Hund
  96 Tests Anmelden zum Anzeigen 9 bis 12 Tage
673,47 €
Details

Am meisten referenzierte PCSK9 ELISA Kits

  1. Mouse (Murine) PCSK9 ELISA Kit für Sandwich ELISA - ABIN2685159 : Seidah, Benjannet, Wickham, Marcinkiewicz, Jasmin, Stifani, Basak, Prat, Chretien: The secretory proprotein convertase neural apoptosis-regulated convertase 1 (NARC-1): liver regeneration and neuronal differentiation. in Proceedings of the National Academy of Sciences of the United States of America 2003 (PubMed)
    Zeige alle 3 Referenzen für ABIN2685159

  2. Human PCSK9 ELISA Kit für Sandwich ELISA - ABIN820112 : Dogan, Akman, Simsek, Ozdem, Comak, Gokceoglu, Kardelen, Koyun: Assessment of left ventricular function by tissue Doppler echocardiography in pediatric chronic kidney disease. in Renal failure 2015 (PubMed)
    Zeige alle 2 Referenzen für ABIN820112

Weitere ELISA Kits für PCSK9 Interaktionspartner

Human Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9) Interaktionspartner

  1. Low LDL cholesterol levels due to PCSK9 and HMGCR (zeige HMGCR ELISA Kits) variants had no causal effect on high risk of Alzheimer's disease, vascular dementia, any dementia, or Parkinson's disease; however, low LDL cholesterol levels may have a causal effect in reducing the risk of Alzheimer's disease.

  2. conditions that cause ER stress regardless of their ability to dysregulate ER Ca(2 (zeige CA2 ELISA Kits)+) inhibit PCSK9 secretion, thereby reducing PCSK9-mediated LDLR (zeige LDLR ELISA Kits) degradation and promoting LDLR (zeige LDLR ELISA Kits)-dependent hepatic cholesterol uptake.

  3. Even though LDLR (zeige LDLR ELISA Kits)-R410S and LDLR (zeige LDLR ELISA Kits)-WT were similar in levels of cell surface and total receptor and bound equally well to LDL or extracellular PCSK9, the LDLR (zeige LDLR ELISA Kits)-R410S was resistant to exogenous PCSK9-mediated degradation in endosomes/lysosomes and showed reduced LDL internalization and degradation relative to LDLR (zeige LDLR ELISA Kits)-WT.

  4. Lipid therapy today and tomorrow: anti-PCSK9

  5. First human antibodies were recently approved as the first immunotherapeutic agents for the treatment of severe hypercholesterolemia and in patients with statin intolerance. An additional PCSK9 antibody is presently being studied in phase III clinical trials.[review]

  6. Proprotein convertase subtilisin/kexin type 9 (PCSK9) binds to low-density lipoprotein (LDL) receptors leading to their degradation in the liver. Inhibition of PCSK9 leads to an increase in LDL receptors and as a result to a reduction of LDL cholesterol in blood. [review]

  7. Furthermore, the effect of reduction of LDL-C by proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibition and by the cholesteryl ester transfer protein (CETP (zeige CETP ELISA Kits)) inhibitor anacetrapib on cardiovascular events is currently being investigated in large clinical outcome study programs. [review]

  8. Further information on long-term efficacy, tolerability and cost-effectiveness of PCSK9 inhibition and possibilities of implementation in the healthcare system are awaited from ongoing clinical outcome trials, such as FOURIER, ODYSSEY OUTCOMES, SPIRE 1 (zeige SPIRE1 ELISA Kits) and 2 involving more than 70,000 high-risk patients. [review]

  9. The 2 or 4week subcutaneous therapy with the recently approved antibodies alirocumab and evolocumab for inhibition of proprotein convertase subtilisin-kexin type 9 (PCSK9) reduces low-density lipoprotein cholesterol (LDL-C) in addition to statins and ezetimibe by 50-60 %. [review]

  10. study provides the first evidence that GPC3 (zeige GPC3 ELISA Kits) can modulate the PCSK9 extracellular activity as a competitive binding partner to the LDLR (zeige LDLR ELISA Kits) in HepG2 cells.

Mouse (Murine) Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9) Interaktionspartner

  1. conditions that cause ER stress regardless of their ability to dysregulate ER Ca(2 (zeige CA2 ELISA Kits)+) inhibit PCSK9 secretion, thereby reducing PCSK9-mediated LDLR (zeige LDLR ELISA Kits) degradation and promoting LDLR (zeige LDLR ELISA Kits)-dependent hepatic cholesterol uptake.

  2. Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Single Domain Antibodies Are Potent Inhibitors of Low Density Lipoprotein Receptor (zeige LDLR ELISA Kits) Degradation.

  3. PCSK9 increases hepatic lipid and lipoprotein production via apoE (zeige APOE ELISA Kits)- and LDLR (zeige LDLR ELISA Kits)-dependent mechanisms

  4. Podocyte damage triggers marked inductions in plasma PCSK9, and knockout of Pcsk9 ameliorates dyslipidemia in a mouse model of nephrotic syndrome.

  5. polydatin ameliorates lipid and glucose metabolism in type 2 diabetes mellitus by downregulating PCSK9.

  6. binding of PCSK9 to GRP94 (zeige HSP90B1 ELISA Kits) protects LDLR (zeige LDLR ELISA Kits) from degradation likely by preventing early binding of PCSK9 to LDLR (zeige LDLR ELISA Kits)

  7. The absence of PCSK9 results in a sex- and tissue-specific subcellular distribution of the LDLR (zeige LDLR ELISA Kits) and VLDLR (zeige VLDLR ELISA Kits), which is determined by estradiol levels.

  8. that ox-LDL receptor-1 (zeige OLR1 ELISA Kits) and PCSK9 positively influence each other's expression, especially during an inflammatory reaction

  9. Data show that leptin (zeige LEP ELISA Kits) treatment suppresses proprotein convertase subtilisin/kexin type 9 (PCSK9) in male, but fails to suppress PCSK9 in female.

  10. The Liver Clock Controls Cholesterol Homeostasis through Trib1 (zeige TRIB1 ELISA Kits) Protein-mediated Regulation of PCSK9/Low Density Lipoprotein Receptor (LDLR (zeige LDLR ELISA Kits)) Axis.

PCSK9 Antigen-Profil

Beschreibung des Gens

This gene encodes a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. The encoded protein is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum. The protein may function as a proprotein convertase. This protein plays a role in cholesterol homeostasis and may have a role in the differentiation of cortical neurons. Mutations in this gene have been associated with a third form of autosomal dominant familial hypercholesterolemia (HCHOLA3).

Genbezeichner und Symbole assoziert mit PCSK9

  • proprotein convertase subtilisin/kexin type 9 (pcsk9) Antikörper
  • proprotein convertase subtilisin/kexin type 9 (PCSK9) Antikörper
  • proprotein convertase subtilisin/kexin type 9 (Pcsk9) Antikörper
  • proprotein convertase subtilisin/kexin type 9-like (LOC100620501) Antikörper
  • AI415265 Antikörper
  • AI747682 Antikörper
  • FH3 Antikörper
  • HCHOLA3 Antikörper
  • LDLCQ1 Antikörper
  • NARC-1 Antikörper
  • Narc1 Antikörper
  • PC9 Antikörper

Bezeichner auf Proteinebene für PCSK9

proprotein convertase subtilisin/kexin type 9 , convertase subtilisin/kexin type 9 preproprotein , neural apoptosis regulated convertase 1 , subtilisin/kexin-like protease PC9 , NARC-1 , convertase subtilisin , neural apoptosis-regulated convertase 1 , proprotein convertase 9 , proprotein convertase PC9 , proprotein convertase subtilisin/kexin type 9 preproprotein , Proprotein convertase 9 , Subtilisin/kexin-like protease PC9

GENE ID SPEZIES
495509 Xenopus laevis
100150316 Danio rerio
100544916 Meleagris gallopavo
255738 Homo sapiens
100102 Mus musculus
298296 Rattus norvegicus
424664 Gallus gallus
100731533 Cavia porcellus
717147 Macaca mulatta
100971792 Pan paniscus
456880 Pan troglodytes
100395116 Callithrix jacchus
100620501 Sus scrofa
Ausgewählte Anbieter für PCSK9 (PCSK9) ELISA Kits
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