anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 2 (KCNJ2) Antikörper

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. Zusätzlich bieten wir Ihnen KCNJ2 Proteine (5) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
KCNJ2 3759 P63252
KCNJ2 29712 Q64273
KCNJ2 16518 P35561
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Top anti-KCNJ2 Antikörper auf antikoerper-online.de

Showing 10 out of 94 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human brain tissue, using KCNJ2 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
342,86 €
Details
Human Maus Unkonjugiert AA, ICC, IF, IHC, WB Kir2 1 Rat Brain Membranes Western Blotting. Kir2 Mouse backskin. 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
411,87 €
Details
Human Kaninchen Unkonjugiert FACS, IHC (p), WB Western blot analysis of KCNJ2 Antibody (C-term) (ABIN390913) in NCI-H460 cell line lysates (35 µg/lane). KCNJ2 (arrow) was detected using the purified polyclonal antibody. Western blot analysis of KCNJ2 Antibody (C-term) (ABIN390913) in mouse lung tissue lysates (35 µg/lane). KCNJ2 (arrow) was detected using the purified polyclonal antibody. 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Maus HRP AA, ICC, IF, IHC, WB Immunohistochemistry analysis using Mouse Anti-Kir2.1 Potassium Channel Monoclonal Antibody, Clone S112B-14 . Tissue: backskin. Species: Mouse. Fixation: Bouin's Fixative and paraffin-embedded. Primary Antibody: Mouse Anti-Kir2.1 Potassium Channel Monoclonal Antibody  at 1:100 for 1 hour at RT. Secondary Antibody: FITC Goat Anti-Mouse (green) at 1:50 for 1 hour at RT. Localization: Nuclear expression in the epidermis and hair follicles. Western Blot analysis of Monkey COS transient cell lysate showing detection of Kir2.1 Potassium Channel protein using Mouse Anti-Kir2.1 Potassium Channel Monoclonal Antibody, Clone S112B-14 . Load: 15 µg. Block: 1.5% BSA for 30 minutes at RT. Primary Antibody: Mouse Anti-Kir2.1 Potassium Channel Monoclonal Antibody  at 1:1000 for 2 hours at RT. Secondary Antibody: Sheep Anti-Mouse IgG: HRP for 1 hour at RT. 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
453,77 €
Details
Human Maus FITC AA, ICC, IF, IHC, WB Immunohistochemistry analysis using Mouse Anti-Kir2.1 Potassium Channel Monoclonal Antibody, Clone S112B-14 . Tissue: backskin. Species: Mouse. Fixation: Bouin's Fixative and paraffin-embedded. Primary Antibody: Mouse Anti-Kir2.1 Potassium Channel Monoclonal Antibody  at 1:100 for 1 hour at RT. Secondary Antibody: FITC Goat Anti-Mouse (green) at 1:50 for 1 hour at RT. Localization: Nuclear expression in the epidermis and hair follicles. Western Blot analysis of Monkey COS transient cell lysate showing detection of Kir2.1 Potassium Channel protein using Mouse Anti-Kir2.1 Potassium Channel Monoclonal Antibody, Clone S112B-14 . Load: 15 µg. Block: 1.5% BSA for 30 minutes at RT. Primary Antibody: Mouse Anti-Kir2.1 Potassium Channel Monoclonal Antibody  at 1:1000 for 2 hours at RT. Secondary Antibody: Sheep Anti-Mouse IgG: HRP for 1 hour at RT. 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
458,56 €
Details
Human Maus Alkaline Phosphatase (AP) AA, ICC, IF, IHC, WB Immunohistochemistry analysis using Mouse Anti-Kir2.1 Potassium Channel Monoclonal Antibody, Clone S112B-14 . Tissue: backskin. Species: Mouse. Fixation: Bouin's Fixative and paraffin-embedded. Primary Antibody: Mouse Anti-Kir2.1 Potassium Channel Monoclonal Antibody  at 1:100 for 1 hour at RT. Secondary Antibody: FITC Goat Anti-Mouse (green) at 1:50 for 1 hour at RT. Localization: Nuclear expression in the epidermis and hair follicles. Western Blot analysis of Monkey COS transient cell lysate showing detection of Kir2.1 Potassium Channel protein using Mouse Anti-Kir2.1 Potassium Channel Monoclonal Antibody, Clone S112B-14 . Load: 15 µg. Block: 1.5% BSA for 30 minutes at RT. Primary Antibody: Mouse Anti-Kir2.1 Potassium Channel Monoclonal Antibody  at 1:1000 for 2 hours at RT. Secondary Antibody: Sheep Anti-Mouse IgG: HRP for 1 hour at RT. 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
460,95 €
Details
Human Maus Biotin AA, ICC, IF, IHC, WB Immunohistochemistry analysis using Mouse Anti-Kir2.1 Potassium Channel Monoclonal Antibody, Clone S112B-14 . Tissue: backskin. Species: Mouse. Fixation: Bouin's Fixative and paraffin-embedded. Primary Antibody: Mouse Anti-Kir2.1 Potassium Channel Monoclonal Antibody  at 1:100 for 1 hour at RT. Secondary Antibody: FITC Goat Anti-Mouse (green) at 1:50 for 1 hour at RT. Localization: Nuclear expression in the epidermis and hair follicles. Western Blot analysis of Monkey COS transient cell lysate showing detection of Kir2.1 Potassium Channel protein using Mouse Anti-Kir2.1 Potassium Channel Monoclonal Antibody, Clone S112B-14 . Load: 15 µg. Block: 1.5% BSA for 30 minutes at RT. Primary Antibody: Mouse Anti-Kir2.1 Potassium Channel Monoclonal Antibody  at 1:1000 for 2 hours at RT. Secondary Antibody: Sheep Anti-Mouse IgG: HRP for 1 hour at RT. 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
463,34 €
Details
Human Maus PE AA, ICC, IF, IHC, WB Immunohistochemistry analysis using Mouse Anti-Kir2.1 Potassium Channel Monoclonal Antibody, Clone S112B-14 . Tissue: backskin. Species: Mouse. Fixation: Bouin's Fixative and paraffin-embedded. Primary Antibody: Mouse Anti-Kir2.1 Potassium Channel Monoclonal Antibody  at 1:100 for 1 hour at RT. Secondary Antibody: FITC Goat Anti-Mouse (green) at 1:50 for 1 hour at RT. Localization: Nuclear expression in the epidermis and hair follicles. Western Blot analysis of Monkey COS transient cell lysate showing detection of Kir2.1 Potassium Channel protein using Mouse Anti-Kir2.1 Potassium Channel Monoclonal Antibody, Clone S112B-14 . Load: 15 µg. Block: 1.5% BSA for 30 minutes at RT. Primary Antibody: Mouse Anti-Kir2.1 Potassium Channel Monoclonal Antibody  at 1:1000 for 2 hours at RT. Secondary Antibody: Sheep Anti-Mouse IgG: HRP for 1 hour at RT. 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
464,54 €
Details
Human Maus Streptavidin AA, ICC, IF, IHC, WB Immunohistochemistry analysis using Mouse Anti-Kir2.1 Potassium Channel Monoclonal Antibody, Clone S112B-14 . Tissue: backskin. Species: Mouse. Fixation: Bouin's Fixative and paraffin-embedded. Primary Antibody: Mouse Anti-Kir2.1 Potassium Channel Monoclonal Antibody  at 1:100 for 1 hour at RT. Secondary Antibody: FITC Goat Anti-Mouse (green) at 1:50 for 1 hour at RT. Localization: Nuclear expression in the epidermis and hair follicles. Western Blot analysis of Monkey COS transient cell lysate showing detection of Kir2.1 Potassium Channel protein using Mouse Anti-Kir2.1 Potassium Channel Monoclonal Antibody, Clone S112B-14 . Load: 15 µg. Block: 1.5% BSA for 30 minutes at RT. Primary Antibody: Mouse Anti-Kir2.1 Potassium Channel Monoclonal Antibody  at 1:1000 for 2 hours at RT. Secondary Antibody: Sheep Anti-Mouse IgG: HRP for 1 hour at RT. 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
465,74 €
Details
Human Maus PerCP AA, ICC, IF, IHC, WB Immunohistochemistry analysis using Mouse Anti-Kir2.1 Potassium Channel Monoclonal Antibody, Clone S112B-14 . Tissue: backskin. Species: Mouse. Fixation: Bouin's Fixative and paraffin-embedded. Primary Antibody: Mouse Anti-Kir2.1 Potassium Channel Monoclonal Antibody  at 1:100 for 1 hour at RT. Secondary Antibody: FITC Goat Anti-Mouse (green) at 1:50 for 1 hour at RT. Localization: Nuclear expression in the epidermis and hair follicles. Western Blot analysis of Monkey COS transient cell lysate showing detection of Kir2.1 Potassium Channel protein using Mouse Anti-Kir2.1 Potassium Channel Monoclonal Antibody, Clone S112B-14 . Load: 15 µg. Block: 1.5% BSA for 30 minutes at RT. Primary Antibody: Mouse Anti-Kir2.1 Potassium Channel Monoclonal Antibody  at 1:1000 for 2 hours at RT. Secondary Antibody: Sheep Anti-Mouse IgG: HRP for 1 hour at RT. 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
466,94 €
Details

KCNJ2 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

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Am meisten referenzierte anti-KCNJ2 Antikörper

  1. Mammalian Monoclonal KCNJ2 Primary Antibody für ISt, IHC - ABIN1304735 : DiFranco, Yu, Quiñonez, Vergara: Inward rectifier potassium currents in mammalian skeletal muscle fibres. in The Journal of physiology 2015 (PubMed)
    Show all 9 Pubmed References

  2. Human Polyclonal KCNJ2 Primary Antibody für EIA, IHC (fro) - ABIN1107936 : Hinard, Belin, Konig, Bader, Bernheim: Initiation of human myoblast differentiation via dephosphorylation of Kir2.1 K+ channels at tyrosine 242. in Development (Cambridge, England) 2008 (PubMed)

  3. Dog (Canine) Polyclonal KCNJ2 Primary Antibody für WB - ABIN2177159 : Zhao, Xu, Yun, Zhao, Li, Gong, Yuan, Yan, Zhang, Ding, Wang, Zhang, Dong, Xiu, Yang, Liu, Xue, Li: Chronic obstructive sleep apnea causes atrial remodeling in canines: mechanisms and implications. in Basic research in cardiology 2014 (PubMed)

Weitere Antikörper gegen KCNJ2 Interaktionspartner

Human Potassium Inwardly-Rectifying Channel, Subfamily J, Member 2 (KCNJ2) Interaktionspartner

  1. We report a novel KCNJ2 sequence variant (p.Y145C) in a family with diagnosed Andersen-Tawil syndrome.

  2. Combined inhibition of IKr and IKur produced a synergistic anti-arrhythmic effect in both forms of SQT3. In conclusion, this study provides mechanistic insights into atrial proarrhythmia with SQT3 Kir2.1 mutations and highlights possible pharmacological strategies for management of SQT3-linked AF.

  3. Data suggest that an R204A mutation disrupts the characteristic cytoplasmic domain subunit interface salt bridges in Kir2.1 reducing apparent sensitivity of channel activity to ligand PIP2 (phosphatidylinositol bisphosphate).

  4. These findings suggest that KCNJ2 plays an important role in the pathophysiology of Thyrotoxic Periodic Paralysis in Korean Graves' Disease patients with Thyrotoxic Periodic Paralysis .

  5. Nav1.5 (zeige SCN5A Antikörper) N-terminal domain binding to alpha1-syntrophin (zeige SNTA1 Antikörper) increases membrane density of human Kir2.1, Kir2.2 (zeige KCNJ12 Antikörper) and Nav1.5 (zeige SCN5A Antikörper) channels

  6. Kir2.1 may participate in macrophage maturation and differentiation, and play a key role in lipid uptake and foam cell formation through modulating the expression of scavenger receptors.

  7. a Korean family with Andersen-Tawil syndrome with a G215D mutation of the KCNJ2 gene revealed by diagnostic exome sequencing, is reported.

  8. Chloroethylclonidine interact with Kir2.1 channels in the cytoplasmic pore.

  9. Variability has been found in a three-generation family with Pierre Robin sequence, acampomelic campomelic dysplasia, and intellectual disability due to a novel approximately 1 Mb deletion upstream of SOX9 (zeige SOX9 Antikörper), and including KCNJ2 and KCNJ16 (zeige KCNJ16 Antikörper).

  10. Patients with Dilated Cardiomyopathy and Sustained Monomorphic Ventricular Tachycardia Show Up-Regulation of KCNN3 (zeige KCNN3 Antikörper) and KCNJ2 Genes and CACNG8 (zeige CACNG8 Antikörper)-Linked Left Ventricular Dysfunction

Mouse (Murine) Potassium Inwardly-Rectifying Channel, Subfamily J, Member 2 (KCNJ2) Interaktionspartner

  1. Our results support the concept that endothelial cell Kir2 channels boost vasodilatory signals that are generated by Ca(2 (zeige CA2 Antikörper)+) -dependent activation of IK and SK channels.

  2. Results suggest that a promyogenic cell adhesion molecule (zeige MCAM Antikörper) Cdo (zeige CDO1 Antikörper) signaling is critical for Inward rectifier potassium channel Kir2.1 activities in the induction of myogenic differentiation.

  3. The data suggest that microglial Kir2.1 channels may represent novel therapeutic targets to inhibit excessive reactive oxygen species production by primed microglia in brain pathology.

  4. Three pairs of weak interactions precisely regulate the G-loop gate of Kir2.1 channel.

  5. Suggest that Kir2.1 channels, in part, account for hyperpolarization and associated absence of tone in urinary bladder arterioles.

  6. This finding represents the first functional evidence for a significant role of the dystrophin (zeige DMD Antikörper)-associated protein complex in the regulation of Kir2.x channels.

  7. Intracellular Mg(2 (zeige MCOLN1 Antikörper)+) and SPM (zeige NPC1 Antikörper) therefore may have a synergistic action on the pore-blocking effect, presumably via prohibition of the outward exit of the higher-affinity blocking SPM (zeige NPC1 Antikörper) by the lower-affinity Mg(2 (zeige MCOLN1 Antikörper)+).

  8. Consistent with a role of the K(+) current in amplifying the sensory response, entry of protons through the Zn(2+)-sensitive conductance produces a transient block of the KIR2.1 current.

  9. Mouse neutrophils express functional Kir2.1 channels from bone marrow and liver.

  10. A184R mutation in the inner end of the bundle crossing region of Kir2.1 not only abolishes the inward rectifying features of spermine block but also tends to close the channel pore.

Cow (Bovine) Potassium Inwardly-Rectifying Channel, Subfamily J, Member 2 (KCNJ2) Interaktionspartner

  1. Hypoxic stress up-regulates Kir2.1 expression and facilitates cell proliferation in brain capillary endothelial cells.

  2. Kir2.1 may mediate native Kir (zeige GEM Antikörper) currents responsible for setting resting membrane potential in bovine parotid cells and might be, at least in part, involved in spontaneous secretion in ruminant parotid glands.

Rabbit Potassium Inwardly-Rectifying Channel, Subfamily J, Member 2 (KCNJ2) Interaktionspartner

  1. There were substantial transmural gradients in Cav1.2 (zeige CACNA1C Antikörper), KChIP2 (zeige KCNIP2 Antikörper), ERG (zeige KCNH2 Antikörper), KvLQT1 (zeige KCNQ1 Antikörper), Kir2.1, NCX1 (zeige SLC8A1 Antikörper), SERCA2a (zeige ATP2A2 Antikörper) and RyR2 (zeige RYR2 Antikörper) at the mRNA and, in some cases, protein level-in every case the mRNA or protein was more abundant in the epicardium than the endocardium.

KCNJ2 Antigen-Profil

Protein Überblick

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Mutations in this gene have been associated with Andersen syndrome, which is characterized by periodic paralysis, cardiac arrhythmias, and dysmorphic features.

Genbezeichner und Symbole assoziert mit KCNJ2

  • inward rectifier potassium channel (IRK1) Antikörper
  • potassium inwardly-rectifying channel, subfamily J, member 2 (KCNJ2) Antikörper
  • potassium inwardly-rectifying channel, subfamily J, member 2 (Kcnj2) Antikörper
  • ATFB9 Antikörper
  • HHBIRK1 Antikörper
  • HHIRK1 Antikörper
  • IRK-1 Antikörper
  • IRK1 Antikörper
  • Kcnf1 Antikörper
  • KCNJ2 Antikörper
  • Kir2.1 Antikörper
  • LQT7 Antikörper
  • SQT3 Antikörper

Bezeichner auf Proteinebene für KCNJ2

IRK-1 , inward rectifier K(+) channel Kir2.1 , inward rectifier potassium channel 2 , potassium channel, inwardly rectifying subfamily J member 2 , cardiac inward rectifier potassium channel , hIRK1 , inward rectifier K+ channel KIR2.1 , RBL-IRK1 , BIK , inward rectifier potassium channel cIRK1 , cardiac inward rectifier KIR2.1 , inwardly rectifying potassium channel Kir2.1 , inward rectifier potassium channel Kir2.1 , inwardly-rectifying potassium channel Kir2.1

GENE ID SPEZIES
397293 Sus scrofa
3759 Homo sapiens
29712 Rattus norvegicus
16518 Mus musculus
281883 Bos taurus
396328 Gallus gallus
403717 Canis lupus familiaris
100135566 Cavia porcellus
100008987 Oryctolagus cuniculus
574189 Macaca mulatta
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