Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1) ELISA Kits

Peptidyl-prolyl cis/trans isomerases (PPIases) catalyze the cis/trans isomerization of peptidyl-prolyl peptide bonds. Zusätzlich bieten wir Ihnen Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 Antikörper (219) und Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 Proteine (21) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
PIN1 241593  
PIN1 5300 Q13526
Anti-Ratte PIN1 PIN1 298696  
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Top Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 ELISA Kits auf antikoerper-online.de

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Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human 0.39 pg/mL 1.56-100 pg/mL Typical standard curve 96 Tests Anmelden zum Anzeigen 11 bis 15 Tage
772,39 €
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Human 34 pg/mL 78-5000 pg/mL   96 Tests Anmelden zum Anzeigen 6 bis 8 Tage
800,38 €
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Rind (Kuh)
  96 Tests Anmelden zum Anzeigen 13 bis 17 Tage
945,85 €
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Maus
  96 Tests Anmelden zum Anzeigen 13 bis 17 Tage
945,85 €
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Weitere ELISA Kits für Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 Interaktionspartner

Mouse (Murine) Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1) Interaktionspartner

  1. Direct delivery of recombinant Pin1 via fibroin nanoparticle encapsulated cationic lipid complex successfully rescued osteoblast differentiation of pin-1 deficient cells.

  2. Pin1 plays important role in the cell cycle progression and increase oval cells proliferation which may be crucial in chronic liver injury.

  3. in vivo functional analyses of Pin1 in the GFAP (zeige GFAP ELISA Kits)-tTA;TRE (zeige TREH ELISA Kits)-SmoA1 mouse model of Hedgehog (zeige SHH ELISA Kits)-driven medulloblastoma demonstrate that the loss of Pin1 impairs tumor development and dramatically increases survival.

  4. Data, including data from studies conducted with knockout mice, suggest that Pin1 (prolyl isomerase 1) expression in pancreatic beta-cells is markedly elevated in obesity from diet high in fat/sucrose; Pin1 appears to be involved in proliferation of beta-cells and in regulation of secretion of insulin (zeige INS ELISA Kits); Pin1 interacts with Sik2 (salt-inducible kinase 2 (zeige SIK2 ELISA Kits)) to regulate calcium signaling.

  5. Pin1 knockout in lupus-prone MRL lpr mi (zeige TLR7 ELISA Kits)ce pre (zeige TLR9 ELISA Kits)vents expres (zeige IRAK1 ELISA Kits)sion o (zeige IRF7 ELISA Kits)f lupus phenotype.

  6. By interacting with PSD-95 (zeige DLG4 ELISA Kits), Pin1 dampens PSD-95 (zeige DLG4 ELISA Kits) ability to complex with NMDARs, thus negatively affecting NMDAR (zeige GRIN1 ELISA Kits) signaling and spine morphology.

  7. Oral administration of brown algae polyphenol, a Pin1 inhibitor, reduced fat buildup in mice.

  8. The findings provide evidence for a putative novel role of PIN1 in the development of the nociceptive system and indicate phosphorylation-mediated conformational changes as a mechanism for regulating the PRRXL1 role in the process.

  9. Data show that peptidyl-prolyl isomerase (zeige PPI ELISA Kits) (Pin1) inhibition inhibits high glucose (HG)-induced cardiac fibroblasts (CFs) proliferation and migration.

  10. Pin1 knock-out mice exhibited disturbed neuronal projections from the cerebral cortex and reduced white matter tracks.

Xenopus laevis Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1) Interaktionspartner

  1. Pin1 is an essential factor regulating CPEB degradation

  2. Pin1 binding is required for the inactivation of XeWee1B at M phase, presumably causing isomerization of the phospho-TP motif and thereby impairing the function of the Wee (zeige WEE1 ELISA Kits)-box

Human Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1) Interaktionspartner

  1. High PIN1 expression is associated with stomach neoplasms.

  2. Pin1 is a novel regulator of ATF1 (zeige AFT1 ELISA Kits) at Thr184.

  3. The dynamic basis for signal propagation in Pin1 N-terminal binding domain WW has been described.

  4. The endoplasmic reticulum (ER) stress decreased Pin1 expression through p53 (zeige TP53 ELISA Kits) activation, and this mechanism may be associated with ER stress-induced cell death. These data reported here support the importance of Pin1 as a potential target molecule mediating tumor development.

  5. our data suggested that miR (zeige MLXIP ELISA Kits)-874-3p plays a tumour suppressive role in HCC (zeige FAM126A ELISA Kits) through down-regulation of PIN1.

  6. in in silico gene expression analysis of human T-ALL samples we observed a significant correlation between Pin1 and Notch3 (zeige NOTCH3 ELISA Kits) expression levels, which may further suggest a key role of the newly identified Notch3 (zeige NOTCH3 ELISA Kits)-Pin1 axis in T-cell Acute Lymphoblastic Leukemia (T-ALL) aggressiveness and progression. Thus, combined suppression of Pin1 and Notch3 (zeige NOTCH3 ELISA Kits) proteins may be exploited as an additional target therapy for T-ALL

  7. The study demonstrates the oncogenic role of PIN1 in NPC (zeige NPC1 ELISA Kits) tumorigenesis, and shows that its overexpression can enhance tumor cell growth via the upregulation of cyclinD1.

  8. Pin1 expression was decreased remarkably in temporal lobe epilepsy patients compared to controls.

  9. Data, including data from studies conducted with knockout mice, suggest that PIN1 (prolyl isomerase 1) expression in pancreatic beta-cells is markedly elevated in obesity from diet high in fat/sucrose; PIN1 appears to be involved in proliferation of beta-cells and in regulation of secretion of insulin (zeige INS ELISA Kits); PIN1 interacts with Sik2 (salt-inducible kinase 2 (zeige SIK2 ELISA Kits)) to regulate calcium signaling.

  10. Knockdown of PIN1 potently blocks TLR-7 (zeige TLR7 ELISA Kits)/TLR-9 (zeige TLR9 ELISA Kits)/Pin1/IRAK-1 (zeige IRAK1 ELISA Kits)/IRF-7 (zeige IRF7 ELISA Kits) signaling in vitro.

Cow (Bovine) Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1) Interaktionspartner

  1. The data provide the first evidence that Pin 1 expression in the granulosa cells but not the theca cells changes during follicular development, and that FSH (zeige BRD2 ELISA Kits) stimulate the expression of the Pin 1 gene.

Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1) Antigen-Profil

Beschreibung des Gens

Peptidyl-prolyl cis/trans isomerases (PPIases) catalyze the cis/trans isomerization of peptidyl-prolyl peptide bonds. This gene encodes one of the PPIases, which specifically binds to phosphorylated ser/thr-pro motifs to catalytically regulate the post-phosphorylation conformation of its substrates. The conformational regulation catalyzed by this PPIase has a profound impact on key proteins involved in the regulation of cell growth, genotoxic and other stress responses, the immune response, induction and maintenance of pluripotency, germ cell development, neuronal differentiation, and survival. This enzyme also plays a key role in the pathogenesis of Alzheimer's disease and many cancers. Multiple alternatively spliced transcript variants have been found for this gene.

Genbezeichner und Symbole assoziert mit PIN1

  • protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1, retrogene 1 (Pin1rt1) Antikörper
  • peptidylprolyl cis/trans isomerase, NIMA-interacting 1 (pin1-b) Antikörper
  • peptidylprolyl cis/trans isomerase, NIMA-interacting 1 (pin1) Antikörper
  • peptidylprolyl cis/trans isomerase, NIMA-interacting 1 (pin1-a) Antikörper
  • peptidylprolyl cis/trans isomerase, NIMA-interacting 1 (PIN1) Antikörper
  • peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (ppiD) Antikörper
  • peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PITG_11123) Antikörper
  • peptidylprolyl cis/trans isomerase, NIMA-interacting 1 (Pin1) Antikörper
  • protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1 (Pin1) Antikörper
  • 0610025L01Rik Antikörper
  • D9Bwg1161e Antikörper
  • DOD Antikörper
  • OTTMUSG00000014964 Antikörper
  • pin1 Antikörper
  • Pin1-ps1 Antikörper
  • pin1a Antikörper
  • pin1b Antikörper
  • Pin1l Antikörper
  • UBL5 Antikörper

Bezeichner auf Proteinebene für PIN1

peptidylprolyl cis/trans isomerase, NIMA-interacting 1 , peptidylprolyl cis/trans isomerase, NIMA-interacting 1, pseudogene 1 , prolyl isomerase Pin1 b , prolyl isomerase Pin1 , peptidylprolyl cis/trans isomerase, NIMA-interacting 1 b , protein (peptidylprolyl cis/trans isomerase) NIMA-interacting 1 , peptidylprolyl cis/trans isomerase, NIMA-interacting 1 a , peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 , PPIase Pin1 , protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1 , rotamase Pin1 , peptidyl-prolyl cis-trans isomerase Pin1

GENE ID SPEZIES
241593 Mus musculus
399385 Xenopus laevis
493472 Xenopus (Silurana) tropicalis
503670 Xenopus laevis
711095 Macaca mulatta
745021 Pan troglodytes
5807350 Sorangium cellulosum So ce56
9476290 Phytophthora infestans T30-4
5300 Homo sapiens
484963 Canis lupus familiaris
298696 Rattus norvegicus
535470 Bos taurus
100512827 Sus scrofa
23988 Mus musculus
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