anti-Peptidyl Arginine Deiminase, Type II (PADI2) Antikörper

PADI2 encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. Zusätzlich bieten wir Ihnen Peptidyl Arginine Deiminase, Type II Proteine (18) und Peptidyl Arginine Deiminase, Type II Kits (14) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
PADI2 11240 Q9Y2J8
PADI2 18600 Q08642
PADI2 29511 P20717
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Top anti-Peptidyl Arginine Deiminase, Type II Antikörper auf antikoerper-online.de

Showing 10 out of 67 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-PADI2 Antibody Titration: </b>0.2-1 ug/ml<br><b>Positive Control: </b>Jurkat cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert WB PADI2 Antibody (C-term) (ABIN658290) western blot analysis in MDA-MB231 cell line lysates (35 µg/lane). This demonstrates the PADI2 antibody detected the PADI2 protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Rind (Kuh) Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Human Kaninchen Unkonjugiert ELISA, ICC, IF, IHC, IP, WB   100 μL Anmelden zum Anzeigen 6 bis 7 Tage
$320.60
Details
Human Maus Unkonjugiert ELISA, WB Detection limit for recombinant GST tagged PADI2 is approximately 0.3 ng/mL as a capture antibody. 0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
$450.00
Details
Human Kaninchen Unkonjugiert EIA, IHC (fro), IP, WB   0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
$555.50
Details
Human Kaninchen Unkonjugiert ELISA, WB 50 μg Anmelden zum Anzeigen 2 bis 3 Tage
$433.13
Details
Human Kaninchen Unkonjugiert ELISA, WB   100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$449.17
Details
Human Kaninchen Unkonjugiert ELISA, ICC, IP, WB   100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$485.80
Details
Human Kaninchen Unkonjugiert WB PADI2 antibody used at 0.5 ug/ml to detect target protein. 50 μg Anmelden zum Anzeigen 2 bis 3 Tage
$473.93
Details

PADI2 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Rat (Rattus)


Am meisten referenzierte anti-Peptidyl Arginine Deiminase, Type II Antikörper

  1. Human Monoclonal PADI2 Primary Antibody für ELISA, WB - ABIN564891 : Blachère, Parveen, Fak, Frank, Orange: Inflammatory but not apoptotic death of granulocytes citrullinates fibrinogen. in Arthritis research & therapy 2015 (PubMed)

Weitere Antikörper gegen Peptidyl Arginine Deiminase, Type II Interaktionspartner

Human Peptidyl Arginine Deiminase, Type II (PADI2) Interaktionspartner

  1. Data suggest that protein-arginine deiminase 2 (PADI2) suppresses the proliferation of colonic epithelial cells through catalysis of protein citrullination, and that downregulation of PADI2 expression might therefore contribute to colon carcinogenesis.

  2. Downregulation of PADI2 is an early event in the pathogenesis of colorectal cancer associated with poor prognosis and points toward a possible role of citrullination in modulating tumor cells and their microenvironment.

  3. Multiple proteins citrullinated by hypoxia-induced PADs were identified. In addition, the extracellular domain of vascular endothelial growth factor receptor 2 was citrullinated by human PAD2 in vitro. CONCLUSION: Our data may contribute to understanding of pathophysiology of malignant gliomas from the aspects of protein citrullination.

  4. Deimination of myelin basic protein (MBP) by peptidylarginine deiminase (PAD) prevents its binding to the proteasome and decelerates its degradation by the proteasome in mammalian cells. Potential anticancer drug tetrazole analogue of chloramidine 2, at concentrations greater than 1 microM inhibits the enzymatic activity of PAD in vitro.

  5. this study shows that a miR (zeige MLXIP Antikörper)-4728 downregulates PADI2, a novel rheumatoid arthritis risk gene

  6. We identified the presence of PADI3 (zeige PADI3 Antikörper) mRNA expression in synovial tissue and PADI2 and PADI4 (zeige PADI4 Antikörper) mRNA expressions in fibroblast-like synoviocytes from patients with rheumatoid arthritis.

  7. Protein arginine deiminase 2 binds six calcium ions in an ordered fashion.

  8. PAD2 activity was significantly higher in cell-free synovial fluid of rheumatoid arthritis patients compared to osteoarthritis patients.

  9. PAD2 activity was detected in synovial fluid samples from patients with rheumatoid arthritis.

  10. Report increased levels of extracellular PAD2 in the lungs of smokers.

Cow (Bovine) Peptidyl Arginine Deiminase, Type II (PADI2) Interaktionspartner

Mouse (Murine) Peptidyl Arginine Deiminase, Type II (PADI2) Interaktionspartner

  1. Taken together, our study is the first to indicate the potential role of Padi2 as an angiogenesis-regulating gene. The characterization of Padi2 and other genes in associated pathways may provide new understanding of angiogenesis regulation and novel targets for diagnosis and treatment of a wide variety of angiogenesis-dependent diseases.

  2. GPx7 (zeige GPX7 Antikörper) is an unusual CysGPx catalyzing the peroxidatic cycle by a one Cys (zeige DNAJC5 Antikörper) mechanism in which GSH and PDI (zeige PDIA3 Antikörper) are alternative substrates.

  3. Results suggest that PADI2 may function as an important new biomarker for HER2/ERBB2 (zeige ERBB2 Antikörper)+ tumors and that Cl-amidine represents a new candidate for breast cancer therapy.

  4. Activation of the P2X7 purinergic receptor (P2X7 (zeige P2RX7 Antikörper)) by the inflammatory danger signal ATP induces PAD2 activity and robust protein citrullination in mast cells.

  5. different subcellular compartmentalization of PADi2 and citrullinated proteins may have different physiological roles in normal and neurodegenerative conditions

  6. PAD2 interacts with IKKgamma (zeige IKBKG Antikörper) and suppresses NF-kappaB (zeige NFKB1 Antikörper) activity.

  7. Results suggest that peptidylarginine deiminase 2-catalyzed citrullination is not essential to the development of experimental autoimmune encephalomyelitis.

  8. An increase in citrullinated proteins resulting from increased PAD2 and 4 is an important change in the pathogenesis of multiple sclerosis.

  9. This study suggests that accumulated citrullinated proteins and abnormal activation of PAD2 may function in the pathogenesis of prion (zeige PRNP Antikörper) diseases and serve as potential therapeutic targets.

  10. elevated levels of the pro-inflammatory cytokine TNF-alpha and nuclear histone deimination support initiation of demyelination by increased PAD activity

Peptidyl Arginine Deiminase, Type II (PADI2) Antigen-Profil

Protein Überblick

This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages. This enzyme is thought to play a role in the onset and progression of neurodegenerative human disorders, including Alzheimer disease and multiple sclerosis, and it has also been implicated in glaucoma pathogenesis. This gene exists in a cluster with four other paralogous genes.

Genbezeichner und Symbole assoziert mit PADI2

  • peptidyl arginine deiminase, type II (PADI2) Antikörper
  • peptidyl arginine deiminase, type II (padi2) Antikörper
  • peptidyl arginine deiminase, type II (LOC100357368) Antikörper
  • peptidyl arginine deiminase, type II (Padi2) Antikörper
  • mKIAA0994 Antikörper
  • PAD-H19 Antikörper
  • PAD2 Antikörper
  • PADI2 Antikörper
  • Pdi Antikörper
  • Pdi2 Antikörper

Bezeichner auf Proteinebene für PADI2

peptidyl arginine deiminase, type II , protein-arginine deiminase type-2-like , peptidlyarginine deiminase type II , peptidylarginine deiminase II , protein arginine deiminase , protein-arginine deiminase type II , protein-arginine deiminase type-2 , peptidyl arginine deiminase, type 2 , PAD type II , peptidyl arginine deiminase, type II; PAD type II

GENE ID SPEZIES
456527 Pan troglodytes
711044 Macaca mulatta
100050025 Equus caballus
100125112 Xenopus (Silurana) tropicalis
100357368 Oryctolagus cuniculus
100437331 Pongo abelii
100473552 Ailuropoda melanoleuca
11240 Homo sapiens
380061 Xenopus laevis
428172 Gallus gallus
617851 Bos taurus
18600 Mus musculus
29511 Rattus norvegicus
487414 Canis lupus familiaris
100621356 Sus scrofa
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