anti-Neighbor of BRCA1 Gene 1 (NBR1) Antikörper

The protein encoded by NBR1 was originally identified as an ovarian tumor antigen monitored in ovarian cancer. Zusätzlich bieten wir Ihnen Neighbor of BRCA1 Gene 1 Kits (6) und Neighbor of BRCA1 Gene 1 Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
NBR1 4077 Q14596
NBR1 17966 P97432
NBR1 303554 Q501R9
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Top anti-Neighbor of BRCA1 Gene 1 Antikörper auf antikoerper-online.de

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Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-Nbr1 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:1562500<br><b>Positive Control: </b>Mouse Spleen WB Suggested Anti-Nbr1 <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500 <br /> Positive Control: Mouse Spleen 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Human Maus Unkonjugiert WB NBR1 monoclonal antibody (M01), clone 6B11. Western Blot analysis of NBR1 expression in PC-12. Detection limit for recombinant GST tagged NBR1 is approximately 0.1 ng/mL as a capture antibody. 0.1 mg Anmelden zum Anzeigen 12 bis 16 Tage
454,76 €
Details
Human Maus Unkonjugiert WB Western blot analysis of NBR1 over-expressed 293 cell line, cotransfected with NBR1 Validated Chimera RNAi used as specificity and loading control. Western Blot analysis of NBR1 expression in transfected 293T cell line by NBR1 monoclonal antibody (M05), clone 5C3. Lane 1: NBR1 transfected lysate(107.4 KDa). Lane 2: Non-transfected lysate. 100 μg Anmelden zum Anzeigen 12 bis 16 Tage
454,76 €
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), SimWes, WB Western Blot: NBR1 Antibody [NBP1-71703] - WB analysis of NBR1 in HepG2 cell lysates. Western Blot: NBR1 Antibody [NBP1-71703] - WB analysis of 30 ug whole cell lysate of HeLa cells using NBR1 antibody. 0.1 mL Anmelden zum Anzeigen 2 bis 4 Tage
311,00 €
Details
Human Maus Unkonjugiert ELISA, WB Detection limit for recombinant GST tagged NBR1 is approximately 0.1ng/ml as a capture antibody. Western Blot detection against Immunogen (36.19 KDa) . 100 μg Anmelden zum Anzeigen 7 bis 8 Tage
369,60 €
Details
Human Maus Unkonjugiert ELISA, WB Western Blot detection against Immunogen (36.56 KDa) . 50 μL Anmelden zum Anzeigen 7 bis 8 Tage
241,60 €
Details
Human Maus Unkonjugiert WB Western Blot analysis of NBR1 expression in transfected 293T cell line by NBR1 MaxPab polyclonal antibody.<br><br>Lane 1: NBR1 transfected lysate(106.26 KDa).<br>Lane 2: Non-transfected lysate.<br> 50 μg Anmelden zum Anzeigen 7 bis 8 Tage
369,60 €
Details
Human Kaninchen Unkonjugiert ELISA, WB   100 μL Anmelden zum Anzeigen 13 Days
154,33 €
Details
Human Kaninchen Unkonjugiert IHC, IHC (p), WB Western Blot: NBR1 Antibody [NBP2-19481] - Sample (30 ug of whole cell lysate) A: Jurkat 7. 5% SDS PAGE gel, diluted at 1:1000. Immunohistochemistry-Paraffin: NBR1 Antibody [NBP2-19481] - Immunohistochemical analysis of paraffin-embedded Breast ca, using antibody at 1:250 dilution. 0.1 mL Anmelden zum Anzeigen 3 bis 6 Tage
341,00 €
Details
Human Kaninchen Unkonjugiert IF, IHC, IP, WB 100 μL Anmelden zum Anzeigen 12 Days
392,86 €
Details

NBR1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-Neighbor of BRCA1 Gene 1 Antikörper

  1. Human Monoclonal NBR1 Primary Antibody für ELISA, WB - ABIN517601 : Mardakheh, Yekezare, Machesky, Heath: Spred2 interaction with the late endosomal protein NBR1 down-regulates fibroblast growth factor receptor signaling. in The Journal of cell biology 2009 (PubMed)
    Show all 7 Pubmed References

  2. Human Polyclonal NBR1 Primary Antibody für ICC, IF - ABIN4337974 : Cullup, Kho, Dionisi-Vici, Brandmeier, Smith, Urry, Simpson, Yau, Bertini, McClelland, Al-Owain, Koelker, Koerner, Hoffmann, Wijburg, ten Hoedt, Rogers, Manchester, Miyata, Hayashi, Said, Soler et al.: Recessive mutations in EPG5 cause Vici syndrome, a multisystem disorder with defective autophagy. ... in Nature genetics 2012 (PubMed)
    Show all 4 Pubmed References

  3. Human Polyclonal NBR1 Primary Antibody für ELISA, WB - ABIN517598 : Mostowy, Sancho-Shimizu, Hamon, Simeone, Brosch, Johansen, Cossart: p62 and NDP52 proteins target intracytosolic Shigella and Listeria to different autophagy pathways. in The Journal of biological chemistry 2011 (PubMed)
    Show all 2 Pubmed References

  4. Human Polyclonal NBR1 Primary Antibody für WB - ABIN517599 : Kuo, Chen, Baron, Onder, Loewer, Almeida, Weismann, Xu, Houghton, Gao, Daley, Doxsey: Midbody accumulation through evasion of autophagy contributes to cellular reprogramming and tumorigenicity. in Nature cell biology 2011 (PubMed)
    Show all 2 Pubmed References

Weitere Antikörper gegen Neighbor of BRCA1 Gene 1 Interaktionspartner

Human Neighbor of BRCA1 Gene 1 (NBR1) Interaktionspartner

  1. NBR1 is not required for PARK2 (zeige PARK2 Antikörper)-dependent mitophagy.

  2. The NBR1 depletion impairs FA turnover and decreases targeting of autophagosomes to FAs (zeige FAS Antikörper), whereas ectopic expression of autophagy-competent, but not autophagy-defective, NBR1 enhances FA disassembly and reduces FA lifetime during migration.

  3. NBR1 positively correlates with adipose inflammation in human obese patients. (zeige MAP3K3 Antikörper)

  4. Analysis of muscle biopsies (zeige GSK3b Antikörper)of sporadic inclusion body myositis (sIBM) patients revealed a strong decrease of NBR1 phosphorylation in muscles of sIBM patients that directly correlated with the severity of protein aggregation.

  5. The C-terminal fragments of SQSTM1 and NBR1 exhibited a dominant-negative effect against native SQSTM1/NBR1, probably by competing for LC3 and ubiquitin chain binding.

  6. structure of the ubiquitin-associated (UBA) domain of human autophagy receptor NBR1 and its interaction with ubiquitin and polyubiquitin (zeige UBB Antikörper)

  7. results suggest that NBR1 is the specific autophagy receptor for pexophagy.

  8. These findings suggest that NBR1 is involved in the formation of cytoplasmic inclusions in alpha-synucleinopathy.

  9. The structural ensemble representing each of the two sequential folding transition transition states of the PB1 (zeige SMR3A Antikörper) domain of NBR1 has been calculated using experimental Phi values and biased molecular dynamics simulations.

  10. Autophagy-related NBR1 protein is not involved in the formation/degradation of neuronal intranuclear inclusions in neurodegenerative diseases.

Mouse (Murine) Neighbor of BRCA1 Gene 1 (NBR1) Interaktionspartner

  1. NBR1 is increased in adipose tissue macrophages in obese mice. The NBR1-MEKK3 (zeige MAP3K3 Antikörper) complex is important in JNK (zeige MAPK8 Antikörper) activation in macrophages.

  2. NBR1 phosphorylation by GSK3 (zeige GSK3b Antikörper) at Thr586 prevents the aggregation of ubiquitinated proteins and their selective autophagic degradation.

  3. In a mouse model of Huntington disease (zeige HTT Antikörper), NBR1 protein levels were decreased in all brain regions analyzed early in the disease, whereas at late stages they accumulated in the striatum and hippocampus, but not in the cortex.

  4. MURF2 (zeige TRIM55 Antikörper) expression parallels that of the autophagy-associated proteins LC3 (zeige MAP1LC3A Antikörper), p62/SQSTM1 (zeige SQSTM1 Antikörper) and nbr1

  5. Results define Nbr1 as a negative regulator of ligand-mediated receptor tyrosine kinase (zeige ERBB3 Antikörper) degradation and reveal the interplay between its various regions for protein localization and function.

  6. NBR1 is a novel PB1 (zeige GPR97 Antikörper) adapter in Th2 differentiation and asthma.

  7. might contribute to the metastasis of ovarian cancer to the peritoneum by initiating cell attachment to the mesothelial epithelium via binding to mesothelin (zeige MSLN Antikörper)

  8. The nbr1 UBA domain binds to lysine-48 and -63 linked polyubiquitin-B (zeige UBB Antikörper) chains. Nbr1 also binds to the autophagic effector protein LC3 (zeige MAP1LC3A Antikörper)-A via a novel binding site.

  9. findings suggest a critical function for NBR1 in the regulation of receptor trafficking and provide a mechanism for down-regulation of signaling by Spred2 (zeige SPRED2 Antikörper) via NBR1.

Neighbor of BRCA1 Gene 1 (NBR1) Antigen-Profil

Protein Überblick

The protein encoded by this gene was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled coil motif, which is present in many genes with transformation potential, but the function of this protein is unknown. This gene is located on a region of chromosome 17q21.1 that is in close proximity to tumor suppressor gene BRCA1. Three alternatively spliced variants encoding the same protein have been identified for this gene.

Genbezeichner und Symbole assoziert mit NBR1

  • neighbor of brca1 gene 1 (nbr1) Antikörper
  • neighbor of BRCA1 gene 1 (nbr1) Antikörper
  • neighbor of BRCA1 gene 1 (NBR1) Antikörper
  • neighbor of BRCA1 gene 1 (LOC100354979) Antikörper
  • neighbor of Brca1 gene 1 (Nbr1) Antikörper
  • 1A1-3B Antikörper
  • Ca125 Antikörper
  • fa99f08 Antikörper
  • M17S2 Antikörper
  • MGC69008 Antikörper
  • mKIAA0049 Antikörper
  • NBR1 Antikörper
  • RGD1311421 Antikörper
  • wu:fa99f08 Antikörper

Bezeichner auf Proteinebene für NBR1

neighbor of BRCA1 gene 1 , next to BRCA1 gene 1 protein , next to BRCA1 gene 1 protein-like , cell migration-inducing gene 19 protein , membrane component chromosome 17 surface marker 2 , membrane component, chromosome 17, surface marker 2 (ovarian carcinoma antigen CA125) , migration-inducing protein 19 , neighbor of BRCA1 gene 1 protein , protein 1A1-3B , membrane component chromosome 17 surface marker 2 homolog , next to the Brca1 , ovarian carcinoma antigen CA125

GENE ID SPEZIES
337168 Danio rerio
379658 Xenopus laevis
420007 Gallus gallus
455047 Pan troglodytes
480509 Canis lupus familiaris
515032 Bos taurus
100051928 Equus caballus
100354979 Oryctolagus cuniculus
100393407 Callithrix jacchus
100581568 Nomascus leucogenys
100625110 Sus scrofa
4077 Homo sapiens
17966 Mus musculus
303554 Rattus norvegicus
100174370 Pongo abelii
Ausgewählte Anbieter für anti-Neighbor of BRCA1 Gene 1 (NBR1) Antikörper
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