NBR1 Antikörper
Kurzübersicht für NBR1 Antikörper (ABIN4901991)
Target
Alle NBR1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- NBR1 is a protein encoded by the NBR1 gene which is approximately 107,4 kDa. NBR1 is localised to the cytoplasm and is involved in animal mitophagy. It contains a B-box/coiled-coil motif and functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. NBR1 is expressed in the nervous system, bone marrow, lung and muscle. Mutations in the NBR1 gene may result in inclusion body myositis and synucleinopathy. STJ98902 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This primary antibody detects endogenous NBR1 protein.
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Spezifität
- The antibody detects endogenous NBR1 protein.
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Produktmerkmale
- Mouse Monoclonal to NBR1.
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
- Recombinant peptide derived from NBR1.
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Applikationshinweise
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WB 1:500-2000
ELISA 1:10000-20000 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze/thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C, and avoid repeat freeze-thaw cycles.
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- NBR1 (Neighbor of BRCA1 Gene 1 (NBR1))
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Andere Bezeichnung
- NBR1
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Molekulargewicht
- 120kDa
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Gen-ID
- 4077
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UniProt
- Q14596
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Pathways
- Autophagie
Target
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