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Mucin 5 Subtype B Proteine (MUC5B)

MUC5B encodes a member of the mucin family of proteins, which are highly glycosylated macromolecular components of mucus secretions. Zusätzlich bieten wir Ihnen MUC5B Antikörper (85) und MUC5B Kits (39) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
MUC5B 74180  
MUC5B 727897 Q9HC84
MUC5B 309114  
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Top MUC5B Proteine auf antikoerper-online.de

Showing 8 out of 11 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
HOST_Escherichia coli (E. coli) Ratte His tag,GST tag 100 μg Anmelden zum Anzeigen 13 bis 17 Tage
710,48 €
Details
HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Anmelden zum Anzeigen 13 bis 17 Tage
600,00 €
Details
HOST_Escherichia coli (E. coli) Maus His tag   100 μg Anmelden zum Anzeigen 13 bis 17 Tage
731,43 €
Details
HOST_Escherichia coli (E. coli) Rind (Kuh) T7 tag,His tag   100 μg Anmelden zum Anzeigen 13 bis 17 Tage
746,67 €
Details
HOST_Escherichia coli (E. coli) Human Unkonjugiert   100 μg Anmelden zum Anzeigen 7 bis 14 Tage
818,45 €
Details
HOST_Escherichia coli (E. coli) Maus Unkonjugiert   100 μg Anmelden zum Anzeigen 7 bis 14 Tage
923,21 €
Details
HOST_Escherichia coli (E. coli) Ratte Unkonjugiert   100 μg Anmelden zum Anzeigen 7 bis 14 Tage
897,02 €
Details

MUC5B Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Mouse (Murine)

Human ,
,
Rat (Rattus)

Weitere Proteine zu Mucin 5 Subtype B (MUC5B) Interaktionspartnern

Mouse (Murine) Mucin 5 Subtype B (MUC5B) Interaktionspartner

  1. Reduced levels of Muc5b in aged mice may be contribute to decreased mucociliary clearance.

  2. Both compounds down regulated mucin (zeige SLC13A2 Proteine) 5 subtype B, and peptidoglycan recognition protein 1 (zeige PGLYRP1 Proteine) in vaginal tissue

  3. Expressions of Orai1 (zeige TMEM132A Proteine), Muc5b, IL-4 (zeige IL4 Proteine), IL-5 (zeige IL5 Proteine), IL-13 (zeige IL13 Proteine) and IL-33 (zeige IL33 Proteine) were up-regulated in the allergic state and IL-33 (zeige IL33 Proteine) increased the levels of Muc5b, IL-4 (zeige IL4 Proteine), IL-5 (zeige IL5 Proteine) and IL-13 (zeige IL13 Proteine), but did not influence proliferation of T cells.

  4. deleting either the Muc5ac or Muc5b gene is insufficient to create an observable dry eye phenotype on the ocular surface of these mice.

  5. mouse Muc5b (but not Muc5ac) is required for mucociliary clearance, for controlling infections in the airways and middle ear, and for maintaining immune homeostasis in mouse lungs, whereas Muc5ac is dispensable

  6. Muc5b was detected in all mammary tumors analyzed from MMTV-ras mice

  7. Muc5b is a target gene of transcription factors (TTF-1, GATA-6) involved in lung differentiation programs during development and carcinogenesis. TTF-1 is a strong repressor of Muc5b.

  8. analysis of Muc5ac and Muc5b production during prenatal and postnatal murine lung development

  9. Acidic pH drives middle ear epithelial Muc5b gene expression in vitro, which perhaps explains how laryngopharyngeal reflux can contribute to otitis media.

  10. The isolation and characterization of the mouse Muc5b mucin (zeige SLC13A2 Proteine) gene (mMuc5b), determined its complete cDNA sequence, its genomic organization, and chromosomal localization and expression.

Human Mucin 5 Subtype B (MUC5B) Interaktionspartner

  1. a critical regulatory domain that contains the MUC5B promoter variant and has a highly conserved forkhead box protein A2 (FOXA2 (zeige FOXA2 Proteine)) binding motif, is identified.

  2. There is no evidence of major proteolytic processing of D-domains during the production of the mature secreted polymeric mucin (zeige SLC13A2 Proteine) in normal and cystic fibrosis (zeige S100A8 Proteine) primary bronchial epithelial cells.

  3. MUC5B was significantly more often detected in middle ear effusion fluid relative to MUC5AC. MUC5B presence was statistically associated with mucoid effusions relative to serous effusions.

  4. Results collectively indicate unique links between dual-specificity phosphatase 28 (DUSP28) and mucins MUC5B/MUC16 and their roles in pancreatic cancer.

  5. Study provides evidence showing that MUC5B expression in cancer cells contributes to certain tumorigenic properties of breast cancer cells, such as cell growth, adhesion, clonogenic ability and drug chemo-resistance.

  6. this study shows that histamine activated the NF-kappaB pathway, contributing to MUC5B overproduction and secretion in nasal epithelial cells

  7. This study showed that MUC5B minor allele predisposes to poradic idiopathic pulmonary fi brosis (spIPF), familial interstitial pneumonia (FIP) and idiopathic non-speci fi c interstitial pneumonia. In spIPF, survival is not in fl uenced by MUC5B alleles. In FIP, MUC5B minor allele predicts better survival.

  8. MUC5B may play a role in the development of pediatric fibrotic lung disease in patients with Surfactant Protein C (zeige SFTPC Proteine) mutations

  9. the MUC5B polymorphism rs35705950 is associated with increased risk of idiopathic pulmonary fibrosis susceptibility, severity, and the decreased overall survival.

  10. The MUC5B promoter polymorphism is the strongest and the most replicated genetic risk factor for Idiopathic pulmonary fibrosis. It is involved in disease pathogenesis through an increase in MUC5B expression in terminal bronchi and honeycombed cysts.

MUC5B Protein Überblick

Protein Überblick

This gene encodes a member of the mucin family of proteins, which are highly glycosylated macromolecular components of mucus secretions. This family member is the major gel-forming mucin in mucus. It is a major contributor to the lubricating and viscoelastic properties of whole saliva, normal lung mucus and cervical mucus. This gene has been found to be up-regulated in some human diseases, including sinus mucosa of chronic rhinosinusitis (CRS), CRS with nasal polyposis, chronic obstructive pulmonary disease (COPD) and H. pylori-associated gastric disease, and it may be involved in the pathogenesis of these diseases.

Genbezeichner und Symbole assoziert mit Mucin 5 Subtype B Proteine (MUC5B)

  • mucin 5, subtype B, tracheobronchial (Muc5b)
  • mucin 5B, oligomeric mucus/gel-forming (MUC5B)
  • mucin 5B, oligomeric mucus/gel-forming (Muc5b)
  • mucin protein (MUC)
  • mucin-5AC (MUC5AC)
  • ovomucin, alpha subunit (LOC395381)
  • 2300002I04Rik Protein
  • A130042M24 Protein
  • AV085033 Protein
  • MG1 Protein
  • MUC-5B Protein
  • MUC5 Protein
  • MUC9 Protein
  • mucin 5b Protein
  • RGD1561983 Protein

Bezeichner auf Proteinebene für Mucin 5 Subtype B Proteine (MUC5B)

cervical mucin MUC5B , high molecular weight salivary mucin MG1 , mucin 5, subtype B, tracheobronchial , mucin-5B , sublingual gland mucin , ovomucin , ovomucin, alpha-subunit

GENE ID SPEZIES
74180 Mus musculus
727897 Homo sapiens
309114 Rattus norvegicus
483656 Canis lupus familiaris
404528 Gallus gallus
789503 Bos taurus
395381 Gallus gallus
Ausgewählte Anbieter für MUC5B Proteine (MUC5B)
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