anti-Lectin, Mannose-Binding, 1 (LMAN1) Antikörper

The protein encoded by LMAN1 is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. Zusätzlich bieten wir Ihnen LMAN1 Kits (7) und LMAN1 Proteine (6) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
LMAN1 3998 P49257
LMAN1 70361 Q9D0F3
LMAN1 116666 Q62902
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Top anti-LMAN1 Antikörper auf antikoerper-online.de

Showing 10 out of 39 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-LMAN1 Antibody Titration: </b>1.25ug/ml<br><b>Positive Control: </b>HepG2 cell lysate 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
288,68 €
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Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
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Hund Maus Unkonjugiert FACS, ICC, IF, IHC, IHC (p), WB Immunohistochemistry-Paraffin: LMAN1 Antibody (1A8) [NBP2-03381] - Staining of paraffin-embedded Human Kidney tissue using anti-LMAN1 mouse monoclonal antibody. Immunocytochemistry/Immunofluorescence: LMAN1 Antibody (1A8) [NBP2-03381] - Staining of COS7 cells transiently transfected by pCMV6-ENTRY LMAN1. 0.1 mL Anmelden zum Anzeigen 3 bis 6 Tage
341,00 €
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Human Kaninchen Unkonjugiert ELISA, WB 0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
387,62 €
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Fledermaus Kaninchen Unkonjugiert WB 100 μg Anmelden zum Anzeigen 11 bis 14 Tage
583,17 €
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Fledermaus Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
653,02 €
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Human Kaninchen Unkonjugiert IHC, IHC (p), WB Immunohistochemistry-Paraffin: LMAN1 Antibody [NBP1-84812] - Staining of human duodenum shows strong cytoplasmic positivity with granular pattern in glandular cells. Western Blot: LMAN1 Antibody [NBP1-84812] - Lane 1: Marker [kDa] 230, 110, 82, 49, 32, 26, 18 Lane 2: Human cell line RT-4 Lane 3: Human cell line U-251MG sp Lane 4: Human plasma (IgG/HSA depleted) Lane 5: Human liver tissue Lane 6: Human tonsil tissue 0.1 mL Anmelden zum Anzeigen 5 bis 8 Tage
335,00 €
Details
Human Maus Unkonjugiert IF, WB Anti-LMAN1 mouse monoclonal antibody (ABIN2453990) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY LMAN1 (RC207088). HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY LMAN1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-LMAN1. 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
366,67 €
Details
Human Maus Unkonjugiert FACS, IF, IHC, WB Anti-LMAN1 mouse monoclonal antibody (ABIN2454009) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY LMAN1 (RC207088). HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY LMAN1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-LMAN1. 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
366,67 €
Details
Human Maus Unkonjugiert WB HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY LMAN1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-LMAN1. 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
366,67 €
Details

LMAN1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-LMAN1 Antikörper

  1. Human Polyclonal LMAN1 Primary Antibody für IHC, IHC (p) - ABIN4331216 : Roeckel, Woerner, Kloor, Yuan, Patsos, Gromes, Kopitz, Gebert: High frequency of LMAN1 abnormalities in colorectal tumors with microsatellite instability. in Cancer research 2009 (PubMed)

  2. Dog (Canine) Monoclonal LMAN1 Primary Antibody für FACS, ICC - ABIN4331217 : Gerondopoulos, Bastos, Yoshimura, Anderson, Carpanini, Aligianis, Handley, Barr: Rab18 and a Rab18 GEF complex are required for normal ER structure. in The Journal of cell biology 2014 (PubMed)

Weitere Antikörper gegen LMAN1 Interaktionspartner

Human Lectin, Mannose-Binding, 1 (LMAN1) Interaktionspartner

  1. Genetic variants in the exon1 of MBL gene per se are not risk factors for Systemic lupus erythematosus (SLE) in South Indian Tamils. However, the association of codon 54 (rs1800450) with medium vessel vasculitis suggests that it may be a genetic modifier of clinical phenotype in SLE.

  2. Mannan-binding lectin (zeige MBL2 Antikörper) reduces CpG DNA-induced inflammatory cytokine production in monocytes.

  3. MMP-9 (zeige MMP9 Antikörper) secretion was reduced in the LMAN1 knockout cell line compared to control cells confirming the functional role of LMAN1.

  4. Authors identified a class of pathogen-derived ERGIC-53 ligands, a lectin-independent basis for their association with ERGIC-53, and a role for ERGIC-53 in the propagation of several highly pathogenic RNA virus families.

  5. Studies indicate that the LMAN1-CRD (zeige CRX Antikörper) contains distinct, separable binding sites for both its partner protein MCFD2 (zeige MCFD2 Antikörper) and the cargo proteins FV/FVIII (zeige F8 Antikörper).

  6. Data indicate that together with its soluble coreceptor MCFD2 (zeige MCFD2 Antikörper), LMAN1 transports coagulation factors V (FV) and VIII (zeige COX8A Antikörper) (FVIII (zeige F8 Antikörper)).

  7. Mutations in LMAN1 lead to F5F8D (combined deficiency of factor V And factor VIII) due to alterations in LMAN1-MCFD2 (zeige MCFD2 Antikörper) complex of coat protein (zeige GOLPH3 Antikörper) (COP (zeige CARD16 Antikörper))II complex trafficking machinery; 70% of F5F8D patients have mutations in LMAN1. [REVIEW]

  8. UBXD1 (zeige UBXN6 Antikörper) modulates the trafficking of ERGIC-53-containing vesicles by controlling the interaction of transport factors with the cytoplasmic tail of ERGIC-53.

  9. Two new mutations at ERGIC-53 gene in a Turkish family.

  10. Data present the crystal structure of the LMAN1/MCFD2 (zeige MCFD2 Antikörper) complex and relate it to patient mutations. Circular dichroism data show that the majority of the substitution mutations give rise to a disordered or severely destabilized MCFD2 (zeige MCFD2 Antikörper) protein.

Mouse (Murine) Lectin, Mannose-Binding, 1 (LMAN1) Interaktionspartner

  1. LMAN1 may play a role in photoreceptor gene transport and homeostasis.

  2. Mice deficient in LMAN1 exhibit FV and FVIII deficiencies and liver accumulation of alpha1-antitrypsin.

  3. surfactant proteins A and D and mannose-binding lectin (zeige MBL2 Antikörper) play roles in inflammation caused by DNA in lungs and other tissues

  4. ERGIC-53 gene transcription is regulated in response to endoplasmic reticulum stress

LMAN1 Antigen-Profil

Protein Überblick

The protein encoded by this gene is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in the gene are associated with a coagulation defect. Using positional cloning, the gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished.

Genbezeichner und Symbole assoziert mit LMAN1

  • lectin, mannose-binding, 1 (LMAN1) Antikörper
  • complexin 3 (cplx3) Antikörper
  • lectin, mannose-binding, 1 (lman1) Antikörper
  • lectin, mannose-binding, 1 (Lman1) Antikörper
  • 2610020P13Rik Antikörper
  • AI326273 Antikörper
  • AU043785 Antikörper
  • C730041J05 Antikörper
  • cpx-iii Antikörper
  • cpxiii Antikörper
  • ERGIC-53 Antikörper
  • ERGIC53 Antikörper
  • F5F8D Antikörper
  • FMFD1 Antikörper
  • gp58 Antikörper
  • lman1 Antikörper
  • lman1-a Antikörper
  • MCFD1 Antikörper
  • MR60 Antikörper
  • P58 Antikörper
  • wu:fc54c09 Antikörper
  • wu:fi36e01 Antikörper
  • Xp58 Antikörper

Bezeichner auf Proteinebene für LMAN1

lectin, mannose-binding, 1 , lectin mannose-binding 1 , ER-Golgi intermediate compartment 53 kDa protein , protein ERGIC-53 , protein ERGIC-53-like , fc54c09 , fi36e01 , endoplasmic reticulum-golgi intermediate compartment protein 53 , intracellular mannose specific lectin , intracellular mannose-specific lectin MR60 , ERGIC-53 protein , intracellular mannose specific lectin MR60

GENE ID SPEZIES
431779 Canis lupus familiaris
455448 Pan troglodytes
496634 Xenopus (Silurana) tropicalis
697449 Macaca mulatta
100021881 Monodelphis domestica
100354112 Oryctolagus cuniculus
100404326 Callithrix jacchus
100475249 Ailuropoda melanoleuca
100562643 Anolis carolinensis
100592766 Nomascus leucogenys
559775 Danio rerio
394295 Xenopus laevis
426849 Gallus gallus
3998 Homo sapiens
476186 Canis lupus familiaris
511649 Bos taurus
70361 Mus musculus
116666 Rattus norvegicus
Ausgewählte Anbieter für anti-LMAN1 (LMAN1) Antikörper
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