anti-Latexin (LXN) Antikörper

LXN encodes the only known protein inhibitor of zinc-dependent metallocarboxypeptidases. Zusätzlich bieten wir Ihnen Latexin Proteine (24) und Latexin Kits (3) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
LXN 56925 Q9BS40
LXN 17035 P70202
LXN 59073 Q64361
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Top anti-Latexin Antikörper auf antikoerper-online.de

Showing 10 out of 171 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>Host: </b>Rabbit<br><b>Target Name: </b>LXN<br><b>Antibody Dilution: </b>1.0ug/ml<br><b>Sample Tissue: </b>A549 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Maus Maus Unkonjugiert WB LXN  western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the LXN antibody detected the LXN protein (arrow). 0.1 mL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert FACS, IHC (p), WB Western blot analysis of Latexin (arrow) using rabbit polyclonal Latexin Antibody (Center) (ABIN388260). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the LXN gene (Lane 2) (Origene Technologies). Formalin-fixed and paraffin-embedded human prostata carcinoma tissue reacted with Latexin antibody (Center) (ABIN388260), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Maus Maus Unkonjugiert WB LXN antibody   western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the LXN  antibody detected the LXN  protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Ziege Unkonjugiert IHC, ELISA, WB ABIN190839 (0.1µg/ml) staining of Rat Brain lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$358.02
Details
Human Ziege Unkonjugiert IHC (p), IHC, ELISA, WB Western Blot: LXN Antibody [ABIN252922] - ABIN252922 (0.1µg/ml) staining of Rat Brain lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Western Blot: Latexin Antibody [ABIN2529226] - Staining of Rat Brain lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$485.88
Details
Fledermaus Ziege Unkonjugiert ELISA, WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$610.50
Details
Human Maus Unkonjugiert FACS, IHC, WB HEK293T cells transfected with either RC202769 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-LXN antibody (ABIN2455184), and then analyzed by flow cytometry. HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY LXN (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-LXN. 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$423.50
Details

LXN Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-Latexin Antikörper

  1. Human Polyclonal Latexin Primary Antibody für IHC (p), IHC - ABIN252922 : de Haan: Latexin is a newly discovered regulator of hematopoietic stem cells. in Nature genetics 2007 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal Latexin Primary Antibody für IHC, ELISA - ABIN190839 : Kadouchi, Sakamoto, Tangjiao, Murakami, Kobayashi, Hoshino, Yamaguchi: Latexin is involved in bone morphogenetic protein-2-induced chondrocyte differentiation. in Biochemical and biophysical research communications 2008 (PubMed)
    Show all 3 Pubmed References

  3. Human Polyclonal Latexin Primary Antibody für IHC - ABIN966502 : Pallarès, Bonet, García-Castellanos, Ventura, Avilés, Vendrell, Gomis-Rüth: Structure of human carboxypeptidase A4 with its endogenous protein inhibitor, latexin. in Proceedings of the National Academy of Sciences of the United States of America 2005 (PubMed)

  4. Human Polyclonal Latexin Primary Antibody für IHC, IHC (p) - ABIN4330408 : Muthusamy, Premi, Soper, Platt, Bosenberg: The hematopoietic stem cell regulatory gene latexin has tumor-suppressive properties in malignant melanoma. in The Journal of investigative dermatology 2013 (PubMed)

Weitere Antikörper gegen Latexin Interaktionspartner

Human Latexin (LXN) Interaktionspartner

  1. Results identified that LXN expression inversely modulates taxane-chemoresistance in the PC-3 (zeige PCSK1 Antikörper) prostate cancer cell line. Inhibition of LXN expression in the bone microenvironment promotes chemoresistance, in part through a methylation-dependent mechanism.

  2. Results show that Lxn expression was clearly decreased in the pancreatic ductal adenocarcinoma tissues suggesting it that as a tumor suppressor that targets CD133-positive cancer cells.

  3. Lxn protein and mRNA expression levels in CD133+ miapaca-2 cells were significantly lower than those in CD133- cells.

  4. latexin is markedly downregulated in hepatocellular carcinoma specimens, compared to adjacent non-cancerous tissues.

  5. CD146 (zeige MCAM Antikörper) and Lxn increased tumor migration and invasion of thyroid cancer.

  6. The hematopoietic stem cell regulatory gene latexin has tumor-suppressive properties in malignant melanoma.

  7. These results are consistent with a tumor suppressor role for latexin.

  8. Latexin expression is lost or greatly reduced in approximately 50% of human leukemia/lymphoma cell lines.

Mouse (Murine) Latexin (LXN) Interaktionspartner

  1. By using an Lxn knockout mouse model, this study found that Lxn inactivation in vivo led to the physiological expansion of the entire hematopoietic hierarchy. Loss of Lxn enhanced the competitive repopulation capacity and survival of hematopoietic stem cells in a cell-intrinsic manner.

  2. Rps3 (zeige RPS3 Antikörper) knockdown increased the radiation sensitivity of FDC-P1, confirming that the mechanism of action of Lxn is mediated by Rps3 (zeige RPS3 Antikörper) pathway.

  3. These results are consistent with a tumor suppressor role for latexin.

  4. Latexin is preferentially expressed in hematopoietic stem cells, and is co-localized with the molecules responsible for the interaction of hematopoietic stem cells with a bone marrow niche.

  5. Data indicate that AAV-mediated latexin transduction or administration of a small molecule carboxypeptidase A inhibitor significantly reduced acetone-evoked nociceptive behavior after SNI.

  6. The crystal structure of mouse latexin, solved at 1.83 A resolution, shows no structural relationship with other carboxypeptidase inhibitors.

  7. Latexin is involved in the transmission of pain, since mice lacking this protein experience reducted pain sensitivity.

  8. promoter polymorphisms between the B6 and D2 alleles may affect Lxn gene expression and consequently influence the population size of hematopoietic stem cells.

  9. These results indicate that latexin is involved in BMP-2 (zeige BMP2 Antikörper)-induced chondrocyte differentiation and plays an important role in skeletogenesis and skeletal regeneration.

Latexin (LXN) Antigen-Profil

Protein Überblick

This gene encodes the only known protein inhibitor of zinc-dependent metallocarboxypeptidases.

Genbezeichner und Symbole assoziert mit anti-Latexin (LXN) Antikörper

  • latexin (lxn) Antikörper
  • latexin (LXN) Antikörper
  • latexin (Lxn) Antikörper
  • ECI Antikörper
  • lxn Antikörper
  • TCI Antikörper
  • wu:fk66c02 Antikörper
  • zgc:103612 Antikörper

Bezeichner auf Proteinebene für anti-Latexin (LXN) Antikörper

latexin , Latexin , MUM , endogenous carboxypeptidase inhibitor , tissue carboxypeptidase inhibitor , ECI , TCI

GENE ID SPEZIES
494053 Danio rerio
703996 Macaca mulatta
771519 Gallus gallus
100195080 Salmo salar
100322883 Felis catus
100346216 Oryctolagus cuniculus
56925 Homo sapiens
17035 Mus musculus
59073 Rattus norvegicus
610062 Canis lupus familiaris
781644 Bos taurus
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