anti-LIM Domain and Actin Binding 1 (LIMA1) Antikörper

LIMA1 encodes a cytoskeleton-associated protein that inhibits actin filament depolymerization and cross-links filaments in bundles. Zusätzlich bieten wir Ihnen LIMA1 Proteine (3) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
LIMA1 300228  
LIMA1 51474 Q9UHB6
LIMA1 65970 Q9ERG0
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Top anti-LIMA1 Antikörper auf antikoerper-online.de

Showing 10 out of 69 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Pferd Kaninchen Unkonjugiert WB Host: Rabbit <br /> Target Name: LIMA1 <br /> Sample Tissue: Human Fetal Heart <br /> Antibody Dilution: 1.0 µg/mL 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-LIMA1 Antibody Titration: 1.0 ug/ml Positive Control: COLO205 Whole Cell 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert EIA, WB Western blot analysis of LIMA1 Antibody (N-term) in A549 cell line lysates (35ug/lane). This demonstrates the LIMA1 antibody detected the LIMA1 protein (arrow). 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert IP Detection of Human EPLIN by Immunoprecipitation. Samples: Whole cell lysate (500 mcg) from DU145 cells. Antibodies: Affinity purified rabbit anti-EPLIN antibody ABIN250691 used at 10 mcg/mg lysate for IP. Detection: Chemiluminescence with an exposure time of 30 seconds. 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$486.94
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: EPLIN Antibody [NBP1-87947] - Staining of human cell line U-2 OS shows positivity in plasma membrane, cytoplasm & cytoskeleton (actin filaments). Western Blot: EPLIN Antibody [NBP1-87947] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$439.69
Details
Human Kaninchen Unkonjugiert IP, IHC, WB Detection of Human EPLIN by Western Blot. Samples: A) Whole cell lysate (50 mcg) from DU145 and SKBR3 cells. B) EPLIN that was immunoprecipitated from 500 mcg of whole cell lysate from DU145 cells. Antibodies: Affinity purified rabbit anti-EPLIN antibody ABIN151503 was used at 0.3 mcg/ml (A) or 1 mcg/ml (B) for WB. In B, EPLIN was immunoprecipitated using another rabbit anti-EPLIN antibody. Detection: Chemiluminescence with exposure times of 30 minutes (A) or 30 seconds (B). Western Blot: EPLIN Antibody  - Samples: Whole cell lysate (0.5 or 1.0 mg per IP reaction; 20% of IP loaded) from MCF7 cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-EPLIN antibody (lot was used at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes. 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$486.94
Details
Rind (Kuh) Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Pferd Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Human Kaninchen Unkonjugiert WB LIMA1 Antibody (N-term)  western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the LIMA1 antibody detected the LIMA1 protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details

LIMA1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Rat (Rattus)


Human , ,
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Mouse (Murine) ,


Am meisten referenzierte anti-LIMA1 Antikörper

  1. Human Polyclonal LIMA1 Primary Antibody für IP, IHC - ABIN250686 : Han, Kosako, Watanabe, Hattori: Extracellular signal-regulated kinase/mitogen-activated protein kinase regulates actin organization and cell motility by phosphorylating the actin cross-linking protein EPLIN. in Molecular and cellular biology 2007 (PubMed)
    Show all 4 Pubmed References

  2. Human Polyclonal LIMA1 Primary Antibody für ICC, IF - ABIN4308788 : Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. in Nature methods 2013 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal LIMA1 Primary Antibody für IP - ABIN250691 : Zhang, Wang, Iqbal, Wang, Osunkoya, Chen, Chen, Shin, Yuan, Wang, Zhau, Chung, Ritenour, Kucuk, Wu: Epidermal growth factor promotes protein degradation of epithelial protein lost in neoplasm (EPLIN), a putative metastasis suppressor, during epithelial-mesenchymal transition. in The Journal of biological chemistry 2013 (PubMed)

  4. Cow (Bovine) Polyclonal LIMA1 Primary Antibody für WB - ABIN2775866 : Maul, Song, Amann, Gerbin, Pollard, Chang: EPLIN regulates actin dynamics by cross-linking and stabilizing filaments. in The Journal of cell biology 2003 (PubMed)

Weitere Antikörper gegen LIMA1 Interaktionspartner

Human LIM Domain and Actin Binding 1 (LIMA1) Interaktionspartner

  1. Data provide evidence that downregulation of EPLIN-alpha may be associated with poor prognosis for patients with epithelial ovarian cancer (EOC), and that this molecule appears to play a tumour suppressor role by inhibition of EOC growth and migration.

  2. EPLIN is functionally linked to molecules like actin and paxillin (zeige PXN Antikörper) and has been implicated in a number of potential pathways to enhance metastatic potential

  3. a major activity of DNp73 is to establish initiation of the invasion-metastasis cascade via EPLIN-dependent IGF1R (zeige IGF1R Antikörper) regulation

  4. EGF (zeige EGF Antikörper) promotes epithelial-mesenchymal transition and induces degradation of EPLIN, a putative suppressor of prostate cancer metastasis.

  5. Together with the findings that EPLIN-alpha inhibits cellular growth and invasion, we conclude that EPLIN-alpha is a tumour suppressor of oesophageal cancer

  6. EPLIN clutch is necessary for stabilization of capillary structures in an angiogenesis model.

  7. EPLIN downregulation promotes epithelial-mesenchymal transition in prostate cancer cells and correlates with clinical lymph node metastasis.

  8. EPLIN functions to link the cadherin-catenin complex to F-actin and simultaneously stabilizes this population of actin fibers, resulting in the establishment of the adhesion

  9. expression of EPLIN-alpha in breast cancer is down-regulated in breast cancer cells .

  10. EPLIN protein may function during cytokinesis to maintain local accumulation of key cytokinesis proteins at the furrow.

Mouse (Murine) LIM Domain and Actin Binding 1 (LIMA1) Interaktionspartner

  1. findings suggest that PINCH-1 (zeige LIMS1 Antikörper) regulates integrin-mediated adhesion of keratinocytes through the interactions with ILK (zeige ILK Antikörper) as well as EPLIN.

  2. Eplin-alpha transcription is regulated by actin-MAL-SRF signalling.

  3. EPLIN may function in growth control by associating with and regulating the actin cytoskeleton

  4. ERK-mediated phosphorylation of EPLIN contributes to actin filament reorganization and enhanced cell motility.

  5. EPLIN functions to link the cadherin-catenin complex to F-actin and simultaneously stabilizes this population of actin fibers, resulting in the establishment of the adhesion

LIMA1 Antigen-Profil

Protein Überblick

This gene encodes a cytoskeleton-associated protein that inhibits actin filament depolymerization and cross-links filaments in bundles. It is downregulated in some cancer cell lines. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and expression of some of the variants maybe independently regulated.

Genbezeichner und Symbole assoziert mit LIMA1

  • LIM domain and actin binding 1 (Lima1) Antikörper
  • LIM domain and actin binding 1 (LIMA1) Antikörper
  • LIM domain and actin binding 1 (lima1) Antikörper
  • 1110021C24Rik Antikörper
  • 3526402A12Rik Antikörper
  • D15Ertd366e Antikörper
  • Eplin Antikörper
  • LIMA1 Antikörper
  • MGC146397 Antikörper
  • SREBP3 Antikörper

Bezeichner auf Proteinebene für LIMA1

LIM domain and actin-binding protein 1 , epithelial protein lost in neoplasm , LIM domain and actin binding 1 , epithelial protein lost in neoplasm beta , 1110021C24Rik , sterol regulatory element binding protein 3 , epithelial protein lost in neoplasm-a , epithelial protein lost in neoplasm-b , mEPLIN

GENE ID SPEZIES
300228 Rattus norvegicus
451892 Pan troglodytes
779798 Xenopus (Silurana) tropicalis
51474 Homo sapiens
65970 Mus musculus
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