LIMA1 Antikörper (Middle Region)
Kurzübersicht für LIMA1 Antikörper (Middle Region) (ABIN2775866)
Target
Alle LIMA1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Verwendungszweck
- LIMA1 Antibody - middle region
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Sequenz
- GVLAASMEAK ASSQQEKEDK PAETKKLRIA WPPPTELGSS GSALEEGIKM
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Homologie
- Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 92%, Rat: 93%
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Produktmerkmale
- This is a rabbit polyclonal antibody against LIMA1. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of Human LIMA1
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8104423
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- prevent freeze-thaw cycles
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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: "EPLIN regulates actin dynamics by cross-linking and stabilizing filaments." in: The Journal of cell biology, Vol. 160, Issue 3, pp. 399-407, (2003) (PubMed).
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- LIMA1 (LIM Domain and Actin Binding 1 (LIMA1))
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Andere Bezeichnung
- LIMA1
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Hintergrund
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Background Information: This gene encodes a cytoskeleton-associated protein that inhibits actin filament depolymerization and cross-links filaments in bundles. It is downregulated in some cancer cell lines. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and expression of some of the variants maybe independently regulated.
Gene Name: LIM domain and actin binding 1
Alternative Symbols: EPLIN, LDLCQ8, SREBP3
Protein Name: LIM domain and actin-binding protein 1
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Molekulargewicht
- 85kDa
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Gen-ID
- 51474
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NCBI Accession
- NP_057441
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UniProt
- Q9UHB6
Target
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