anti-LIM Domain Kinase 2 (LIMK2) Antikörper

There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. Zusätzlich bieten wir Ihnen LIMK2 Proteine (10) und LIMK2 Kits (7) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
LIMK2 3985 P53671
LIMK2 29524 P53670
LIMK2 16886 O54785
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Top anti-LIMK2 Antikörper auf antikoerper-online.de

Showing 10 out of 132 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human brain, using LIMK2 (Phospho-Ser283) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
342,86 €
Details
Human Kaninchen Unkonjugiert WB 100 μg Anmelden zum Anzeigen 8 bis 11 Tage
340,48 €
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Human Kaninchen Unkonjugiert IF, IHC (p), WB 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
352,00 €
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: LIM kinase 2 Antibody [NBP1-85783] - Staining of human cell line U-251MG shows positivity in cytoplasm & mitochondria. Western Blot: LIM kinase 2 Antibody [NBP1-85783] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp 0.1 mL Anmelden zum Anzeigen 5 bis 8 Tage
335,00 €
Details
Human Ziege Unkonjugiert ELISA, WB   100 μg Anmelden zum Anzeigen 3 bis 4 Tage
349,82 €
Details
Human Kaninchen Unkonjugiert IHC, ELISA, WB Western blot analysis of extracts from COLO205 cells, using LIMK2 (Phospho-Thr505) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using LIMK2 (Phospho-Thr505) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
342,86 €
Details
Human Kaninchen Unkonjugiert ELISA, IF, IHC, WB 100 μL Anmelden zum Anzeigen 13 Days
154,33 €
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Human Kaninchen Unkonjugiert ELISA, WB 100 μL Anmelden zum Anzeigen 13 Days
154,33 €
Details
Human Kaninchen Unkonjugiert ELISA, IF, IHC, WB Western Blot (WB) analysis of specific cells using LIMK-2 Polyclonal Antibody. 100 μL Anmelden zum Anzeigen 13 Days
154,33 €
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC (p), IHC, WB Immunohistochemical analysis of paraffin- embedded human breast carcinoma tissue using LIMK2 (phospho-Thr505) antibody Western blot analysis of extract from NIH/3T3 cells treated or untreated with UV (60min), using LIMK2 (phospho- Thr505) antibody 0.05 mL Anmelden zum Anzeigen 2 bis 4 Tage
291,00 €
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LIMK2 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-LIMK2 Antikörper

  1. Human Polyclonal LIMK2 Primary Antibody für ICC, IF - ABIN4330985 : Kim, Ryu, Kim, Kang: LIM kinase-2 induces programmed necrotic neuronal death via dysfunction of DRP1-mediated mitochondrial fission. in Cell death and differentiation 2014 (PubMed)
    Zeige alle 2 Referenzen für 4330985

  2. Human Polyclonal LIMK2 Primary Antibody für IF, IHC (p) - ABIN196832 : Ohashi, Nagata, Maekawa, Ishizaki, Narumiya, Mizuno: Rho-associated kinase ROCK activates LIM-kinase 1 by phosphorylation at threonine 508 within the activation loop. in The Journal of biological chemistry 2000 (PubMed)
    Zeige alle 2 Referenzen für 196832

  3. Human Polyclonal LIMK2 Primary Antibody für IHC, ELISA - ABIN1532018 : Dunham, Shimizu, Roe, Chissoe, Hunt, Collins, Bruskiewich, Beare, Clamp, Smink, Ainscough, Almeida, Babbage, Bagguley, Bailey, Barlow, Bates, Beasley, Bird, Blakey, Bridgeman, Buck, Burgess, Burrill et al.: The DNA sequence of human chromosome 22. ... in Nature 1999 (PubMed)

Weitere Antikörper gegen LIMK2 Interaktionspartner

Human LIM Domain Kinase 2 (LIMK2) Interaktionspartner

  1. these results suggested that TUG1 mediates cell growth and chemoresistance of SCLC by regulating LIMK2b via EZH2 (zeige EZH2 Antikörper).

  2. LIMK2 (rs149034313) is associated with Behcet's disease. The LIMK2 association is a missense variant with predicted protein damage that may influence functional interactions with proteins involved in cytoskeletal regulation by Rho GTPase (zeige RACGAP1 Antikörper), inflammation mediated by chemokine (zeige CCL1 Antikörper) and cytokine signaling pathways, T cell activation, and angiogenesis.

  3. We observed marked increases in LIM kinase 2 (LIMK2) and cofilin 1 (CFL1 (zeige CFL1 Antikörper)) gene expressions in metabolic syndrome patients.

  4. This study showed that LIMK2 messenger RNA levels was significantly upregulated in subjects with schizophrenia in laminar and cellular samples.

  5. Actin remodelling factor LIMK2 is a key player in the ciliogenesis control network in which YAP (zeige YAP1 Antikörper)/TAZ (zeige TAZ Antikörper) and directional vesicle trafficking are integral components.

  6. Results show that in addition to a potential role in promoting metastasis, changes in LIMK1 (zeige LIMK1 Antikörper) and LIMK2 expression and/or activity might contribute to AR function in prostate cancer via regulation of microtubule cytoskeletal dynamics.

  7. results highlight the exciting possibility of combining specific LIMK2 inhibitors with anticancer drugs in the treatment of multi-drug resistant cancers

  8. LIMK2 expression was reduced in intestinal tumours of cancer-prone mice and in human colorectal cancer cell lines and tumours. LIMK2 expression progressively decreased with advancing stage of colorectal cancer.

  9. Overexpression of LIMK2 is associated with breast cancer growth and invasiveness.

  10. Nf1/LIMK2 interaction and inhibition allows to directly connect neurofibromatosis type I to actin cytoskeleton remodeling.

Mouse (Murine) LIM Domain Kinase 2 (LIMK2) Interaktionspartner

  1. These data suggest that osteoblasts can increase their mechanosensitivity under continuous mechanical stimulation by reducing the actin stress fiber formation through inhibiting the LIMK2 expression.

  2. LIMK2 expression was reduced in intestinal tumours of cancer-prone mice.

  3. LIMK2 activity is required for keratinocyte migration in the developing eyelid.

  4. Using RNAi against LIMK2 to inhibit the cytoskeleton reorganization can promote the expression of c-fos gene and thus enhance the mechanosensitivity of c-fos gene in osteoblasts.

  5. Results suggest that constitutive activation of the Rho-ROCK-LIM (zeige PDLIM5 Antikörper) kinase pathway by extracellular production of lysophosphatidic acid by the action of autotaxin (zeige ENPP2 Antikörper) is required to maintain the large size of lysosomes in visceral endoderm cells.

  6. LIMK-1 (zeige LIMK1 Antikörper)/2 double knockout mice were more severely impaired in both ADF/cofilin (zeige CFL1 Antikörper) phosphorylation and excitatory synaptic function in the CA1 (zeige CA1 Antikörper) region of the hippocampus.

  7. a novel pathway emanating from the TGF-beta type I receptor (zeige TGFBR1 Antikörper) and leading to regulation of actin assembly, via the kinase LIMK2.

LIMK2 Antigen-Profil

Protein Überblick

There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. The protein encoded by this gene is phosphorylated and activated by ROCK, a downstream effector of Rho, and the encoded protein, in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. It is thought that this pathway contributes to Rho-induced reorganization of the actin cytoskeleton. At least three transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit LIMK2

  • LIM domain kinase 2 (limk2) Antikörper
  • LIM domain kinase 2 (LIMK2) Antikörper
  • LIM domain kinase 2 (LOC100223808) Antikörper
  • similar to LIM domain kinase 2 (LIMK2) Antikörper
  • LIM domain kinase 2 (Limk2) Antikörper
  • LIM motif-containing protein kinase 2 (Limk2) Antikörper
  • 9430059K01 Antikörper
  • A930024P04Rik Antikörper
  • C85310 Antikörper
  • LIMK Antikörper
  • LIMK2 Antikörper
  • Limk2a Antikörper
  • Limk2b Antikörper
  • Link2 Antikörper
  • wu:fa97c09 Antikörper
  • wu:fk73e11 Antikörper
  • xlimk2 Antikörper
  • zgc:91990 Antikörper

Bezeichner auf Proteinebene für LIMK2

XLIM-Kinases2 , LIM domain kinase 2 , LIM domain kinase 2-like , LIM motif-containing protein kinase 2 , LIMK-2 , LIM kinase 2 , LIM-containing protein kinase 2a , LIM-containing protein kinase 2t , Limk2t-1 and Limk2t-2

GENE ID SPEZIES
398298 Xenopus laevis
436924 Danio rerio
486363 Canis lupus familiaris
100058419 Equus caballus
100216249 Xenopus (Silurana) tropicalis
100223808 Taeniopygia guttata
100396965 Callithrix jacchus
100586214 Nomascus leucogenys
458970 Pan troglodytes
716614 Macaca mulatta
100478557 Ailuropoda melanoleuca
3985 Homo sapiens
29524 Rattus norvegicus
513539 Bos taurus
396010 Gallus gallus
16886 Mus musculus
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